SEZ6L

SEZ6L
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2YRA
Identifiers
Aliases	SEZ6L , seizure related 6 homolog like
External IDs	OMIM: 607021; MGI: 1935121; HomoloGene: 10895; GeneCards: SEZ6L; OMA:SEZ6L - orthologs
Gene location (Human) Chr. Chromosome 22 (human) [1] Band 22q12.1 Start 26,169,462 bp [1] End 26,383,597 bp [1]
Gene location (Mouse) Chr. Chromosome 5 (mouse) [2] Band 5|5 F Start 112,567,017 bp [2] End 112,725,051 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence endothelial cell lateral nuclear group of thalamus ventricular zone prefrontal cortex buccal mucosa cell dorsolateral prefrontal cortex Region I of hippocampus proper cingulate gyrus anterior cingulate cortex Top expressed in dentate gyrus of hippocampal formation granule cell CA3 field entorhinal cortex primary visual cortex perirhinal cortex superior frontal gyrus nucleus of stria terminalis cerebellar cortex hippocampus proper lateral septal nucleus More reference expression data BioGPS More reference expression data
Orthologs Species Human Mouse Entrez 23544 56747 Ensembl ENSG00000100095 ENSMUSG00000058153 UniProt Q9BYH1 Q6P1D5 RefSeq (mRNA) NM_001184773 NM_001184774 NM_001184775 NM_001184776 NM_001184777 NM_021115 NM_001253916 NM_001253917 NM_019982 RefSeq (protein) NP_001171702 NP_001171703 NP_001171704 NP_001171705 NP_001171706 NP_066938 NP_001171704.1 NP_001240845 NP_001240846 NP_064366 NP_001390215 NP_001390216 NP_001390217 NP_001390218 Location (UCSC) Chr 22: 26.17 – 26.38 Mb Chr 5: 112.57 – 112.73 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Seizure 6-like protein is a protein that in humans is encoded by the SEZ6L gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000100095 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000058153 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: SEZ6L seizure related 6 homolog (mouse)-like".

Further reading

• Gorlov IP, Meyer P, Liloglou T, et al. (2007). "Seizure 6-like (SEZ6L) gene and risk for lung cancer". Cancer Res. 67 (17): 8406–11. doi: 10.1158/0008-5472.CAN-06-4784 . PMID   17804757.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi: 10.1186/gb-2004-5-10-r84 . PMC   545604 . PMID   15461802.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Collins JE, Goward ME, Cole CG, et al. (2003). "Reevaluating Human Gene Annotation: A Second-Generation Analysis of Chromosome 22". Genome Res. 13 (1): 27–36. doi:10.1101/gr.695703. PMC   430954 . PMID   12529303.
• Suzuki H, Gabrielson E, Chen W, et al. (2002). "A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer". Nat. Genet. 31 (2): 141–9. doi:10.1038/ng892. PMID   11992124. S2CID   3038484.
• Nishioka M, Kohno T, Takahashi M, et al. (2001). "Identification of a 428-kb homozygously deleted region disrupting the SEZ6L gene at 22q12.1 in a lung cancer cell line". Oncogene. 19 (54): 6251–60. doi: 10.1038/sj.onc.1204031 . PMID   11175339.
• Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi: 10.1038/990031 . PMID   10591208.
• Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi: 10.1093/dnares/6.1.63 . PMID   10231032.