SEZ6L

SEZ6L
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2YRA
Identifiers
Aliases	SEZ6L , seizure related 6 homolog like
External IDs	OMIM: 607021 MGI: 1935121 HomoloGene: 10895 GeneCards: SEZ6L
Gene location (Human)
Chr.	Chromosome 22 (human)
End	26,383,597 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	112,725,051 bp
RNA expression pattern
	Top expressed in
	ganglionic eminence; ; endothelial cell; ; prefrontal cortex; ; dorsolateral prefrontal cortex; ; Region I of hippocampus proper; ; cingulate gyrus; ; Brodmann area 9; ; hypothalamus; ; cerebellar cortex; ; cerebellar hemisphere;
	Top expressed in
	entorhinal cortex; ; superior frontal gyrus; ; cerebellar cortex; ; hippocampus proper; ; ventromedial nucleus; ; primary motor cortex; ; cingulate gyrus; ; dorsomedial hypothalamic nucleus; ; subiculum; ; medial dorsal nucleus;
	More reference expression data
	; ; ; ;
	More reference expression data
Orthologs
	23544
	56747
	ENSG00000100095
	ENSMUSG00000058153
	Q9BYH1
	Q6P1D5
NM_001184773 ; NM_001184774 ; NM_001184775 ; NM_001184776 ; NM_001184777 ;
	NM_021115
	NM_001253916 ; NM_001253917 ; NM_019982
NP_001171702 ; NP_001171703 ; NP_001171704 ; NP_001171705 ; NP_001171706 ;
	NP_066938 ; NP_001171704.1
NP_001240845 ; NP_001240846 ; NP_064366 ; NP_001390215 ; NP_001390216 ;
	NP_001390217 ; NP_001390218
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 05, 2023

Seizure 6-like protein is a protein that in humans is encoded by the SEZ6L gene.^[5]

Related Research Articles

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000100095 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000058153 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: SEZ6L seizure related 6 homolog (mouse)-like".

Gorlov IP, Meyer P, Liloglou T, et al. (2007). "Seizure 6-like (SEZ6L) gene and risk for lung cancer". Cancer Res. 67 (17): 8406–11. doi: 10.1158/0008-5472.CAN-06-4784 . PMID 17804757.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604 . PMID 15461802.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697 . PMID 12975309.
Collins JE, Goward ME, Cole CG, et al. (2003). "Reevaluating Human Gene Annotation: A Second-Generation Analysis of Chromosome 22". Genome Res. 13 (1): 27–36. doi:10.1101/gr.695703. PMC 430954 . PMID 12529303.
Suzuki H, Gabrielson E, Chen W, et al. (2002). "A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer". Nat. Genet. 31 (2): 141–9. doi:10.1038/ng892. PMID 11992124. S2CID 3038484.
Nishioka M, Kohno T, Takahashi M, et al. (2001). "Identification of a 428-kb homozygously deleted region disrupting the SEZ6L gene at 22q12.1 in a lung cancer cell line". Oncogene. 19 (54): 6251–60. doi: 10.1038/sj.onc.1204031 . PMID 11175339.
Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi: 10.1038/990031 . PMID 10591208.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi: 10.1093/dnares/6.1.63 . PMID 10231032.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000100095 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000058153 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SEZ6L seizure related 6 homolog (mouse)-like".

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SEZ6L

Related Research Articles

References

Further reading