SFRS2IP

SCAF11
Identifiers
Aliases	SCAF11 , CASP11, SFRS2IP, SIP1, SRRP129, SRSF2IP, SR-related CTD associated factor 11
External IDs	OMIM: 603668; MGI: 1919443; HomoloGene: 37957; GeneCards: SCAF11; OMA:SCAF11 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q12 Start 45,919,131 bp [1] End 45,992,120 bp [1]
Gene location (Mouse) Chr. Chromosome 15 (mouse) [2] Band 15|15 F1 Start 96,309,580 bp [2] End 96,358,724 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in buccal mucosa cell epithelium of colon tendon of biceps brachii Achilles tendon lower lobe of lung jejunal mucosa pylorus tonsil oral cavity sural nerve Top expressed in tail of embryo genital tubercle mandibular prominence maxillary prominence epithelium of stomach ankle skin of external ear abdominal wall tibiofemoral joint cumulus cell More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding metal ion binding RNA binding Cellular component nucleolus nucleus nucleoplasm nuclear body Biological process RNA splicing, via transesterification reactions mRNA processing spliceosomal complex assembly RNA splicing Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 9169 72193 Ensembl ENSG00000139218 ENSMUSG00000033228 UniProt Q99590 n/a RefSeq (mRNA) NM_004719 NM_028148 RefSeq (protein) NP_004710 n/a Location (UCSC) Chr 12: 45.92 – 45.99 Mb Chr 15: 96.31 – 96.36 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

SFRS2-interacting protein is a protein that in humans is encoded by the SFRS2IP gene. ^{[5] [6] [7]}

Interactions

SFRS2IP has been shown to interact with U2AF2. ^[6]

References

1. GRCh38: Ensembl release 89: ENSG00000139218 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000033228 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Tanner S, Stagljar I, Georgiev O, Schaffner W, Bourquin JP (Aug 1997). "A novel SR-related protein specifically interacts with the carboxy-terminal domain (CTD) of RNA polymerase II through a conserved interaction domain". Biol Chem. 378 (6): 565–71. doi: 10.1515/bchm.1997.378.6.565 . PMID   9224939.
6. Zhang WJ, Wu JY (Feb 1998). "Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing". Mol Cell Biol. 18 (2): 676–84. doi:10.1128/mcb.18.2.676. PMC   108778 . PMID   9447963.
7. "Entrez Gene: SFRS2IP splicing factor, arginine/serine-rich 2, interacting protein".

Further reading

• Gui JF, Lane WS, Fu XD (1994). "A serine kinase regulates intracellular localization of splicing factors in the cell cycle". Nature. 369 (6482): 678–82. Bibcode:1994Natur.369..678G. doi:10.1038/369678a0. PMID   8208298. S2CID   4275539. Archived from the original on 2020-12-03. Retrieved 2019-12-14.
• van de Craen M, de Jonghe C, van den Brande I, et al. (1999). "Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases" (PDF). FEBS Lett. 445 (1): 149–54. doi:10.1016/S0014-5793(99)00108-8. hdl: 10067/238040151162165141 . PMID   10069390. S2CID   31218178.
• Scanlan MJ, Gordan JD, Williamson B, et al. (1999). "Antigens recognized by autologous antibody in patients with renal-cell carcinoma". Int. J. Cancer. 83 (4): 456–64. doi: 10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5 . PMID   10508479.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi: 10.1073/pnas.0404720101 . PMC   514446 . PMID   15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.