SFRS2IP

SCAF11
Identifiers
Aliases	SCAF11 , CASP11, SFRS2IP, SIP1, SRRP129, SRSF2IP, SR-related CTD associated factor 11
External IDs	OMIM: 603668 MGI: 1919443 HomoloGene: 37957 GeneCards: SCAF11
Gene location (Human)
Chr.	Chromosome 12 (human)
End	45,992,120 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	96,460,843 bp
RNA expression pattern
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	• GO:0001948 protein binding ; • metal ion binding ; • RNA binding ;
Cellular component	• nucleolus ; • nucleus ; • nucleoplasm ; • nuclear body ;
Biological process	• RNA splicing, via transesterification reactions ; • mRNA processing ; • spliceosomal complex assembly ; • RNA splicing ;
	Sources:Amigo / QuickGO
Orthologs
	9169
	72193
	ENSG00000139218
	ENSMUSG00000033228
	Q99590
	n/a
	NM_004719
	NM_028148
	NP_004710
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated May 22, 2021

SFRS2-interacting protein is a protein that in humans is encoded by the SFRS2IP gene.^[5]^[6]^[7]

Interactions

SFRS2IP has been shown to interact with U2AF2.^[6]

Related Research Articles

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Splicing factor, arginine/serine-rich 11 is a protein that in humans is encoded by the SFRS11 gene.

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000139218 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000033228 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Tanner S, Stagljar I, Georgiev O, Schaffner W, Bourquin JP (Aug 1997). "A novel SR-related protein specifically interacts with the carboxy-terminal domain (CTD) of RNA polymerase II through a conserved interaction domain". Biol Chem. 378 (6): 565–71. doi: 10.1515/bchm.1997.378.6.565 . PMID 9224939.
1 2 Zhang WJ, Wu JY (Feb 1998). "Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing". Mol Cell Biol. 18 (2): 676–84. doi:10.1128/mcb.18.2.676. PMC 108778 . PMID 9447963.
↑ "Entrez Gene: SFRS2IP splicing factor, arginine/serine-rich 2, interacting protein".

Gui JF, Lane WS, Fu XD (1994). "A serine kinase regulates intracellular localization of splicing factors in the cell cycle". Nature. 369 (6482): 678–82. doi:10.1038/369678a0. PMID 8208298. S2CID 4275539.
van de Craen M, de Jonghe C, van den Brande I, et al. (1999). "Identification of caspases that cleave presenilin-1 and presenilin-2. Five presenilin-1 (PS1) mutations do not alter the sensitivity of PS1 to caspases". FEBS Lett. 445 (1): 149–54. doi:10.1016/S0014-5793(99)00108-8. hdl: 10067/238040151162165141 . PMID 10069390. S2CID 31218178.
Scanlan MJ, Gordan JD, Williamson B, et al. (1999). "Antigens recognized by autologous antibody in patients with renal-cell carcinoma". Int. J. Cancer. 83 (4): 456–64. doi: 10.1002/(SICI)1097-0215(19991112)83:4<456::AID-IJC4>3.0.CO;2-5 . PMID 10508479.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241 . PMID 12477932.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446 . PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000139218 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000033228 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9224939-5] Tanner S, Stagljar I, Georgiev O, Schaffner W, Bourquin JP (Aug 1997). "A novel SR-related protein specifically interacts with the carboxy-terminal domain (CTD) of RNA polymerase II through a conserved interaction domain". Biol Chem. 378 (6): 565–71. doi: 10.1515/bchm.1997.378.6.565 . PMID 9224939.

[pmid9447963-6] 1 2 Zhang WJ, Wu JY (Feb 1998). "Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing". Mol Cell Biol. 18 (2): 676–84. doi:10.1128/mcb.18.2.676. PMC 108778 . PMID 9447963.

[entrez-7] "Entrez Gene: SFRS2IP splicing factor, arginine/serine-rich 2, interacting protein".

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SFRS2IP

Contents

Interactions

Related Research Articles

References

Further reading