SH3BGRL

SH3BGRL
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1U6T, 1WRY
Identifiers
Aliases	SH3BGRL , HEL-S-115, SH3BGR, SH3 domain binding glutamate rich protein like
External IDs	OMIM: 300190; MGI: 1930849; HomoloGene: 2275; GeneCards: SH3BGRL; OMA:SH3BGRL - orthologs
Gene location (Human) Chr. X chromosome (human) [1] Band Xq21.1 Start 81,202,102 bp [1] End 81,298,547 bp [1]
Gene location (Mouse) Chr. X chromosome (mouse) [2] Band X|X D Start 108,138,971 bp [2] End 108,241,479 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in seminal vesicula tail of epididymis monocyte superficial temporal artery saphenous vein trabecular bone urethra lactiferous duct germinal epithelium popliteal artery Top expressed in medial ganglionic eminence tunica media of zone of aorta ascending aorta olfactory epithelium Epithelium of choroid plexus aortic valve carotid body left lung lobe calvaria submandibular gland More reference expression data BioGPS More reference expression data
Gene ontology Molecular function SH3 domain binding Cellular component cytoplasm extracellular exosome nucleus extracellular space Biological process positive regulation of signal transduction Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 6451 56726 Ensembl ENSG00000131171 ENSMUSG00000031246 UniProt O75368 Q9JJU8 RefSeq (mRNA) NM_003022 NM_019989 RefSeq (protein) NP_003013 NP_064373 Location (UCSC) Chr X: 81.2 – 81.3 Mb Chr X: 108.14 – 108.24 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

SH3 domain-binding glutamic acid-rich-like protein is a protein that in humans is encoded by the SH3BGRL gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000131171 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000031246 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Egeo A, Mazzocco M, Arrigo P, Vidal-Taboada JM, Oliva R, Pirola B, Giglio S, Rasore-Quartino A, Scartezzini P (Jul 1998). "Identification and characterization of a new human gene encoding a small protein with high homology to the proline-rich region of the SH3BGR gene". Biochem Biophys Res Commun. 247 (2): 302–6. doi:10.1006/bbrc.1998.8763. PMID   9642120.
6. "Entrez Gene: SH3BGRL SH3 domain binding glutamic acid-rich protein like".

Further reading

• Dawson SJ, White LA (1992). "Treatment of Haemophilus aphrophilus endocarditis with ciprofloxacin". J. Infect. 24 (3): 317–20. doi:10.1016/S0163-4453(05)80037-4. PMID   1602151.
• Drutel G, Arrang JM, Diaz J, et al. (1996). "Cloning of OL1, a putative olfactory receptor and its expression in the developing rat heart". Recept. Channels. 3 (1): 33–40. PMID   8589991.
• Yin L, Xiang Y, Zhu DY, et al. (2006). "Crystal structure of human SH3BGRL protein: the first structure of the human SH3BGR family representing a novel class of thioredoxin fold proteins". Proteins. 61 (1): 213–6. doi: 10.1002/prot.20523 . PMID   16080146.
• Bruneel A, Labas V, Mailloux A, et al. (2006). "Proteomics of human umbilical vein endothelial cells applied to etoposide-induced apoptosis". Proteomics. 5 (15): 3876–84. doi:10.1002/pmic.200401239. PMID   16130169. S2CID   26007149.
• Majid SM, Liss AS, You M, Bose HR (2006). "The suppression of SH3BGRL is important for v-Rel-mediated transformation". Oncogene. 25 (5): 756–68. doi:10.1038/sj.onc.1209107. PMID   16186799. S2CID   42806147.
• Schulze WX, Deng L, Mann M (2006). "Phosphotyrosine interactome of the ErbB-receptor kinase family". Mol. Syst. Biol. 1 (1): 2005.0008. doi:10.1038/msb4100012. PMC   1681463 . PMID   16729043.