SLC22A13

Last updated
SLC22A13
Identifiers
Aliases SLC22A13 , OAT10, OCTL1, OCTL3, ORCTL-3, ORCTL3, solute carrier family 22 member 13
External IDs OMIM: 604047 MGI: 2143107 HomoloGene: 3140 GeneCards: SLC22A13
Gene location (Human)
Ideogram human chromosome 3.svg
Chr. Chromosome 3 (human) [1]
Human chromosome 3 ideogram.svg
HSR 1996 II 3.5e.svg
Red rectangle 2x18.png
Band 3p22.2Start38,265,812 bp [1]
End38,278,757 bp [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004256

NM_133980

RefSeq (protein)

NP_004247

NP_598741

Location (UCSC) Chr 3: 38.27 – 38.28 Mb Chr 9: 119.19 – 119.21 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Solute carrier family 22 member 13 is a protein that in humans is encoded by the SLC22A13 gene. [5]

Contents

Function

This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 4. The encoded protein is a transmembrane protein involved in the transport of small molecules. This protein can function to mediate urate uptake and is a high affinity nicotinate exchanger in the kidneys and the intestine.

Related Research Articles

SLC22A4 protein-coding gene in the species Homo sapiens

Solute carrier family 22, member 4, also known as SLC22A4, is a human gene; the encoded protein is known as the ergothioneine transporter.

SLC22A2 Protein-coding gene

Solute carrier family 22 member 2 is a protein that in humans is encoded by the SLC22A2 gene.

SLC22A1 protein-coding gene in the species Homo sapiens

Solute carrier family 22 member 1 is a protein that in humans is encoded by the gene SLC22A1.

SLC22A3 protein-coding gene in the species Homo sapiens

Solute carrier family 22 member 3 (SLC22A3) also known as the organic cation transporter 3 (OCT3) or extraneuronal monoamine transporter (EMT) is a protein that in humans is encoded by the SLC22A3 gene.

SLC22A11 protein-coding gene in the species Homo sapiens

Solute carrier family 22 member 11 is a protein that in humans is encoded by the SLC22A11 gene.

SLC22A8 protein-coding gene in the species Homo sapiens

Solute carrier family 22 member 8, or organic anion transporter 3 (OAT3), is a protein that in humans is encoded by the SLC22A8 gene.

SLC22A12 mammalian protein found in Homo sapiens

Solute carrier family 22, member 12, also known as SLC22A12 and URAT1, is a protein which in humans is encoded by the SLC22A12 gene.

SLC22A18 protein-coding gene in the species Homo sapiens

Solute carrier family 22 member 18 is a protein that in humans is encoded by the SLC22A18 gene.

Sodium/myo-inositol cotransporter protein-coding gene in the species Homo sapiens

Sodium/myo-inositol cotransporter is a protein that in humans is encoded by the SLC5A3 gene.

Multidrug and toxin extrusion protein 1 protein-coding gene in the species Homo sapiens

Multidrug and toxin extrusion protein 1 (MATE1), also known as solute carrier family 47 member 1, is a protein that in humans is encoded by the SLC47A1 gene. SLC47A1 belongs to the MATE family of transporters that are found in bacteria, archaea and eukaryotes.

Cationic amino acid transporter 3 protein-coding gene in the species Homo sapiens

Cationic amino acid transporter 3 is a protein that in humans is encoded by the SLC7A3 gene.

SLC2A9 protein-coding gene in the species Homo sapiens

Solute carrier family 2, facilitated glucose transporter member 9 is a protein that in humans is encoded by the SLC2A9 gene.

SLC13A3 protein-coding gene in the species Homo sapiens

Solute carrier family 13 member 3 also called sodium-dependent dicarboxylate transporter (NaDC3) is a protein that in humans is encoded by the SLC13A3 gene.

SLC22A7 protein-coding gene in the species Homo sapiens

Solute carrier family 22 member 7 is a protein that in humans is encoded by the gene SLC22A7.

SLC22A9 protein-coding gene in the species Homo sapiens

Solute carrier family 22 member 9 is a protein that in humans is encoded by the SLC22A9 gene.

SLC6A18 protein-coding gene in the species Homo sapiens

Solute carrier family 6, member 18 also known as SLC6A18 is a protein which in humans is encoded by the SLC6A18 gene.

Organic anion transporter 1 protein-coding gene in the species Homo sapiens

The organic anion transporter 1 (OAT1) also known as solute carrier family 22 member 6 (SLC22A6) is a protein that in humans is encoded by the SLC22A6 gene. It is a member of the organic anion transporter (OAT) family of proteins. OAT1 is a transmembrane protein that is expressed in the brain, the placenta, the eyes, smooth muscles, and the basolateral membrane of proximal tubular cells of the kidneys. It plays a central role in renal organic anion transport. Along with OAT3, OAT1 mediates the uptake of a wide range of relatively small and hydrophilic organic anions from plasma into the cytoplasm of the proximal tubular cells of the kidneys. From there, these substrates are transported into the lumen of the nephrons of the kidneys for excretion. OAT1 homologs have been identified in rats, mice, rabbits, pigs, flounders, and nematodes.

SLC22A25 protein-coding gene in the species Homo sapiens

Solute carrier family 22 member 25 (SLC22A25), also known as organic anion transporter UST6, is a protein that in humans is encoded by the SLC22A25 gene.

SLC17A3 protein-coding gene in the species Homo sapiens

Solute carrier family 17, member 3 is a protein that in humans is encoded by the SLC17A3 gene.

SLC22A14 mammalian protein found in Homo sapiens

Solute carrier family 22 member 14 is a protein that in humans is encoded by the SLC22A14 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000172940 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000074028 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Solute carrier family 22 member 13" . Retrieved 2017-10-05.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.