The TATA-binding protein (TBP) is a general transcription factor that binds specifically to a DNA sequence called the TATA box. This DNA sequence is found about 30 base pairs upstream of the transcription start site in some eukaryotic gene promoters.
Angiogenin (ANG) also known as ribonuclease 5 is a small 123 amino acid protein that in humans is encoded by the ANG gene. Angiogenin is a potent stimulator of new blood vessels through the process of angiogenesis. Ang hydrolyzes cellular RNA, resulting in modulated levels of protein synthesis and interacts with DNA causing a promoter-like increase in the expression of rRNA. Ang is associated with cancer and neurological disease through angiogenesis and through activating gene expression that suppresses apoptosis.
Transcription factor E2F4 is a protein that in humans is encoded by the E2F4 gene.
Platelet-derived growth factor subunit A is a protein that in humans is encoded by the PDGFA gene.
Myocyte-specific enhancer factor 2A is a protein that in humans is encoded by the MEF2A gene. MEF2A is a transcription factor in the Mef2 family. In humans it is located on chromosome 15q26. Certain mutations in MEF2A cause an autosomal dominant form of coronary artery disease and myocardial infarction.
Nuclear factor of activated T-cells 5, also known as NFAT5 and sometimes TonEBP, is a human gene that encodes a transcription factor that regulates the expression of genes involved in the osmotic stress.
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (PP2BB) is an enzyme that in humans is encoded by the PPP3CB gene.
Helicase-like transcription factor is an enzyme that in humans is encoded by the HLTF gene.
Sodium–hydrogen exchanger 2 is a protein that in humans is encoded by the SLC9A2 gene.
Haptoglobin-related protein is a protein that in humans is encoded by the HPR gene. The HPR gene affects hereditary immunity to a non-pathogenic species of African trypanosomes.
Early growth response protein 3 is a protein in humans, encoded by the EGR3 gene.
RING finger protein 38 is a protein that in humans is encoded by the RNF38 gene.
Sodium-dependent phosphate transport protein 2B (NaPi2b) is a protein that in humans is encoded by the SLC34A2 gene.
Forkhead box protein K2 is a protein that in humans is encoded by the FOXK2 gene.
Transcription elongation factor A protein-like 1 is a protein that in humans is encoded by the TCEAL1 gene.
Zinc finger and BTB domain-containing protein 7B is a protein that in humans is encoded by the ZBTB7B gene. ZFP67 is an early growth response gene that encodes a zinc finger-containing transcription factor that binds to the promoter regions of type I collagen genes and has a role in development.[supplied by OMIM]
Zinc finger protein 19 is a protein that in humans is encoded by the ZNF19 gene.
Sodium-coupled neutral amino acid transporter 1 is a protein that in humans is encoded by the SLC38A1 gene.
Early growth response protein 4 (EGR-4), also known as AT133, is a protein that in humans is encoded by the EGR4 gene.
Zinc finger transcription factors or ZF-TFs, are transcription factors composed of a zinc finger-binding domain and any of a variety of transcription-factor effector-domains that exert their modulatory effect in the vicinity of any sequence to which the protein domain binds.
