SLC45A4 | |||||||||||||||||||||||||
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Identifiers | |||||||||||||||||||||||||
Aliases | SLC45A4 , solute carrier family 45 member 4 | ||||||||||||||||||||||||
External IDs | MGI: 2146236 HomoloGene: 69908 GeneCards: SLC45A4 | ||||||||||||||||||||||||
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Orthologs | |||||||||||||||||||||||||
Species | Human | Mouse | |||||||||||||||||||||||
Entrez | |||||||||||||||||||||||||
Ensembl | |||||||||||||||||||||||||
UniProt | |||||||||||||||||||||||||
RefSeq (mRNA) | |||||||||||||||||||||||||
RefSeq (protein) | |||||||||||||||||||||||||
Location (UCSC) | Chr 8: 141.21 – 141.31 Mb | Chr 15: 73.58 – 73.65 Mb | |||||||||||||||||||||||
PubMed search | [3] | [4] | |||||||||||||||||||||||
Wikidata | |||||||||||||||||||||||||
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SLC45A4 is a member of the SLC45 family of solute carriers. Analysis of the protein function in a recombinant yeast expression assay show that it can: (i) transport a disaccharide, sucrose, as well simple sugars such as glucose and fructose (ii) perform secondary active transport in a proton-dependent manner. [5]
It is associated with sugar transport in the spermatozoa. [6] Additionally, it has been identified as a necessary component in the cell death caused of the compound paraquat. [7]
Peptide transporter 1 also known as solute carrier family 15 member 1 (SLC15A1) is a protein that in humans is encoded by SLC15A1 gene. PepT 1 is a solute carrier for oligopeptides. It functions in renal oligopeptide reabsorption and in the intestines in a proton dependent way, hence acting like a cotransporter.
Solute carrier family 23 member 2 is a protein that in humans is encoded by the SLC23A2 gene.
Proton-coupled amino acid transporter 1 is a protein that in humans is encoded by the SLC36A1 gene.
Mitochondrial uncoupling protein 4 is a protein that in humans is encoded by the SLC25A27 gene.
Solute carrier family 15, member 2, also known as SLC15A2, is a human gene.
Monocarboxylate transporter 4 (MCT4) also known as solute carrier family 16 member 3 is a protein that in humans is encoded by the SLC16A3 gene.
Solute carrier family 2, facilitated glucose transporter member 6 is a protein that in humans is encoded by the SLC2A6 gene.
Solute carrier family 2, facilitated glucose transporter member 9 is a protein that in humans is encoded by the SLC2A9 gene.
Solute carrier family 13 member 3 also called sodium-dependent dicarboxylate transporter (NaDC3) is a protein that in humans is encoded by the SLC13A3 gene.
Long-chain fatty acid transport protein 6 is a protein that in humans is encoded by the SLC27A6 gene.
Cationic amino acid transporter 2 is a protein that in humans is encoded by the SLC7A2 gene.
Cationic amino acid transporter 4 is a protein that in humans is encoded by the SLC7A4 gene.
Solute carrier family 6, member 18 also known as SLC6A18 is a protein which in humans is encoded by the SLC6A18 gene.
Monocarboxylate transporter 10, also known as aromatic amino acid transporter 1 and T-type amino acid transporter 1 (TAT1) and solute carrier family 16 member 10 (SLC16A10), is a protein that in humans is encoded by the SLC16A10 gene. SLC16A10 is a member of the solute carrier family.
Proton myo-inositol cotransporter, also known as solute carrier family 2 member 13 is a protein that in humans is encoded by the SLC2A13 gene.
Solute carrier family 2, member 14 is a protein that in humans is encoded by the SLC2A14 gene.
Zinc transporter 3 also known as solute carrier family 30 member 3 is a protein in humans that is encoded by the SLC30A3 gene.
Monocarboxylate transporter 2 (MCT2) also known as solute carrier family 16 member 7 (SLC16A7) is a protein that in humans is encoded by the SLC16A7 gene. MCT2 is a proton-coupled monocarboxylate transporter. It catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate and beta-hydroxybutyrate. It also functions as high-affinity pyruvate transporter.
SLC45A1 is a member of the SLC45 family of solute carriers. Analysis of the protein function in a recombinant yeast expression assay show that it can: (i) transport a disaccharide, such as glucose and sucrose (ii) perform secondary active transport in a proton-dependent manner.
Solute carrier family 22 member 14 is a protein that in humans is encoded by the SLC22A14 gene.