SLC8B1

Last updated
SLC8B1
Identifiers
Aliases SLC8B1 , NCKX6, NCLX, SLC24A6, solute carrier family 8 member B1
External IDs OMIM: 609841 MGI: 2180781 HomoloGene: 41602 GeneCards: SLC8B1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_024959
NM_001330466
NM_001358345

NM_001177594
NM_001177595
NM_133221

RefSeq (protein)

NP_001317395
NP_079235
NP_001345274

NP_001171065
NP_001171066
NP_573484

Location (UCSC) Chr 12: 113.3 – 113.36 Mb Chr 5: 120.65 – 120.67 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 is a protein that in humans is encoded by the SLC8B1 gene. [5]

Contents

Function

SLC24A6 belongs to a family of Potassium-dependent sodium-calcium exchangers that maintain cellular calcium homeostasis through the electrogenic countertransport of 4 sodium ions for 1 calcium ion and 1 potassium ion. [6]

Related Research Articles

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<span class="mw-page-title-main">Sodium–hydrogen antiporter 3</span> Protein-coding gene in the species Homo sapiens

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<span class="mw-page-title-main">Ileal sodium/bile acid cotransporter</span>

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<span class="mw-page-title-main">Chloride potassium symporter 4</span>

Potassium-chloride transporter, member 4 is a chloride potassium symporter protein. It is encoded by the gene SLC12A4.

<span class="mw-page-title-main">Sodium-dependent multivitamin transporter</span>

Sodium-dependent multivitamin transporter is a protein that in humans is encoded by the SLC5A6 gene.

<span class="mw-page-title-main">Solute carrier organic anion transporter family member 1A2</span>

Solute carrier organic anion transporter family member 1A2 is a protein that in humans is encoded by the SLCO1A2 gene.

<span class="mw-page-title-main">Sodium-dependent phosphate transport protein 2B</span>

Sodium-dependent phosphate transport protein 2B (NaPi2b) is a protein that in humans is encoded by the SLC34A2 gene.

<span class="mw-page-title-main">SLC12A7</span> Protein-coding gene in the species Homo sapiens

Solute carrier family 12 member 7 is a protein that in humans is encoded by the SLC12A7 gene.

<span class="mw-page-title-main">Sodium/myo-inositol cotransporter</span> Protein-coding gene in the species Homo sapiens

Sodium/myo-inositol cotransporter is a protein that in humans is encoded by the SLC5A3 gene.

<span class="mw-page-title-main">Anion exchange transporter</span> Protein-coding gene in the species Homo sapiens

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<span class="mw-page-title-main">Sodium/hydrogen exchanger 5</span> Protein-coding gene in the species Homo sapiens

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<span class="mw-page-title-main">Calcium-binding mitochondrial carrier protein Aralar1</span>

Calcium-binding mitochondrial carrier protein Aralar1 is a protein that in humans is encoded by the SLC25A12 gene. Aralar is an integral membrane protein located in the inner mitochondrial membrane. Its primary function as an antiporter is the transport of cytoplasmic glutamate with mitochondrial aspartate across the inner mitochondrial membrane, dependent on the binding of one calcium ion. Mutations in this gene cause early infantile epileptic encephalopathy 39 (EIEE39), symptomized by global hypomyelination of the central nervous system, refractory seizures, and neurodevelopmental impairment. This gene has connections to autism.

<span class="mw-page-title-main">SLC13A2</span>

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Solute carrier family 6, member 18 also known as SLC6A18 is a protein which in humans is encoded by the SLC6A18 gene.

<span class="mw-page-title-main">Calcium-binding mitochondrial carrier protein SCaMC-1</span> Protein-coding gene in the species Homo sapiens

Calcium-binding mitochondrial carrier protein SCaMC-1 is a protein that in humans is encoded by the SLC25A24 gene.

<span class="mw-page-title-main">Sodium/potassium/calcium exchanger 4</span>

Sodium/potassium/calcium exchanger 4 also known as solute carrier family 24 member 4 is a protein that in humans is encoded by the SLC24A4 gene.

<span class="mw-page-title-main">Sodium-dependent phosphate transport protein 2A</span> Protein-coding gene in the species Homo sapiens

Sodium-dependent phosphate transport protein 2A, also known as Na+-Pi cotransporter 2a (NaPi-2a), is a protein in humans that is encoded by the SLC34A1 gene. This gene encodes a member of the type II sodium-phosphate cotransporter family.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000089060 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000032754 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Solute carrier family 8 (sodium/lithium/calcium exchanger), member B1".
  6. Cai X, Lytton J (February 2004). "Molecular cloning of a sixth member of the K+-dependent Na+/Ca2+ exchanger gene family, NCKX6". The Journal of Biological Chemistry. 279 (7): 5867–76. doi: 10.1074/jbc.M310908200 . PMID   14625281.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.