SLFN12L

SLFN12L
Identifiers
Aliases	SLFN12L , schlafen family member 12 like
External IDs	OMIM: 614956; MGI: 1329005; HomoloGene: 133236; GeneCards: SLFN12L; OMA:SLFN12L - orthologs
Gene location (Human) Chr. Chromosome 17 (human) [1] Band 17q12 Start 35,464,249 bp [1] End 35,537,678 bp [1]
Gene location (Mouse) Chr. Chromosome 11 (mouse) [2] Band 11|11 C Start 83,082,156 bp [2] End 83,105,980 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte blood spleen testicle lymph node appendix bone marrow cells tonsil duodenum gallbladder Top expressed in thymus bone marrow granulocyte neck uterus pharynx quadriceps femoris muscle spermatid tongue circulatory system More reference expression data BioGPS n/a
Orthologs Species Human Mouse Entrez 100506736 20557 Ensembl ENSG00000205045 ENSMUSG00000018986 UniProt Q6IEE8 n/a RefSeq (mRNA) NM_001145027 NM_001195790 NM_001363830 NM_011409 RefSeq (protein) NP_001182719 NP_001350759 n/a Location (UCSC) Chr 17: 35.46 – 35.54 Mb Chr 11: 83.08 – 83.11 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Schlafen family member 12 like is a protein that in humans is encoded by the SLFN12L gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000205045 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000018986 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Schlafen family member 12 like" . Retrieved 2020-04-12.

Further reading

• Ferreira MA, Mangino M, Brumme CJ, Zhao ZZ, Medland SE, Wright MJ, Nyholt DR, Gordon S, Campbell M, McEvoy BP, Henders A, Evans DM, Lanchbury JS, Pereyra F, Walker BD, Haas DW, Soranzo N, Spector TD, de Bakker PI, Frazer IH, Montgomery GW, Martin NG (January 2010). "Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control". Am. J. Hum. Genet. 86 (1): 88–92. doi:10.1016/j.ajhg.2009.12.008. PMC   2801744 . PMID   20045101.
• Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC   2896464 . PMID   20379614.
• Ding L, Hayes MM, Photenhauer A, Eaton KA, Li Q, Ocadiz-Ruiz R, Merchant JL (August 2016). "Schlafen 4-expressing myeloid-derived suppressor cells are induced during murine gastric metaplasia". J. Clin. Invest. 126 (8): 2867–80. doi:10.1172/JCI82529. PMC   4966326 . PMID   27427984.