SPACA3

Last updated
SPACA3
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases SPACA3 , 1700025M08Rik, ALLP17, CT54, LYC3, LYZL3, SLLP1, LYZC, sperm acrosome associated 3
External IDs OMIM: 612749; MGI: 1922872; HomoloGene: 18365; GeneCards: SPACA3; OMA:SPACA3 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_173847
NM_001317225
NM_001317226

NM_029367
NM_001359183

RefSeq (protein)

NP_001304154
NP_001304155
NP_776246

NP_083643
NP_001346112

Location (UCSC) Chr 17: 32.97 – 33 Mb Chr 11: 80.75 – 80.76 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Sperm acrosome membrane-associated protein 3 is a protein that in humans is encoded by the SPACA3 gene. It may be involved in adhesion to the egg before the egg is fertilized. [5] [6]

Contents

See also

Related Research Articles

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<span class="mw-page-title-main">PRSS23</span> Protein-coding gene in the species Homo sapiens

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<span class="mw-page-title-main">CST8 (gene)</span> Protein-coding gene in the species Homo sapiens

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<span class="mw-page-title-main">INSL4</span> Protein-coding gene in the species Homo sapiens

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<span class="mw-page-title-main">ACRV1</span> Protein-coding gene in the species Homo sapiens

Acrosomal protein SP-10 is a protein that in humans is encoded by the ACRV1 gene.

<span class="mw-page-title-main">RFX2</span> Protein-coding gene in the species Homo sapiens

DNA-binding protein RFX2 is a protein that in humans is encoded by the RFX2 gene.

<span class="mw-page-title-main">Sperm-associated antigen 8</span> Protein-coding gene in the species Homo sapiens

Sperm-associated antigen 8 is a protein that in humans is encoded by the SPAG8 gene.

<span class="mw-page-title-main">CABYR</span> Protein-coding gene in humans

Calcium-binding tyrosine phosphorylation-regulated protein is a protein that in humans is encoded by the CABYR gene.

<span class="mw-page-title-main">Sperm protein associated with the nucleus, X-linked, family member A1</span> Protein-coding gene in the species Homo sapiens

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<span class="mw-page-title-main">CEP57</span> Protein-coding gene in the species Homo sapiens

Centrosomal protein of 57 kDa is a protein that in humans is encoded by the CEP57 gene. It is also known as translokin.

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Eppin is a protein that in humans is encoded by the SPINLW1 gene.

<span class="mw-page-title-main">CatSper1</span> Protein-coding gene in the species Homo sapiens

CatSper1, is a protein which in humans is encoded by the CATSPER1 gene. CatSper1 is a member of the cation channels of sperm family of protein. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells.

<span class="mw-page-title-main">CYB5R2</span> Protein-coding gene in the species Homo sapiens

Cytochrome b5 reductase 2 is an enzyme that in humans is encoded by the CYB5R2 gene.

A disintegrin and metalloprotease 3, or ADAM3, belongs to a family of peptidase proteins referred to as ADAMs. Many of these are solely found in spermatogenic cells, specifically in the anterior portion of capacitated spermatozoa heads. This membrane protein is critical for crucial steps in fertilization such as migration of sperm through the uterus to the oviduct as well as binding to the zona pellucida. Inactivation of ADAM3 is a cause of male infertility.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000141316 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000053184 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Mandal A, Klotz KL, Shetty J, Jayes FL, Wolkowicz MJ, Bolling LC, Coonrod SA, Black MB, Diekman AB, Haystead TA, Flickinger CJ, Herr JC (Apr 2003). "SLLP1, a unique, intra-acrosomal, non-bacteriolytic, c lysozyme-like protein of human spermatozoa". Biol Reprod. 68 (5): 1525–37. doi: 10.1095/biolreprod.102.010108 . PMID   12606493.
  6. "Entrez Gene: SPACA3 sperm acrosome associated 3".

Further reading