Sperm acrosome membrane-associated protein 3 is a protein that in humans is encoded by the SPACA3 gene. It may be involved in adhesion to the egg before the egg is fertilized. [5] [6]
Zona pellucida sperm-binding protein 3, also known as zona pellucida glycoprotein 3 (Zp-3) or the sperm receptor, is a ZP module-containing protein that in humans is encoded by the ZP3 gene. ZP3 is the glycoprotein in the zona pellucida most important for inducting the acrosome reaction of sperm cells at the beginning of fertilization.
Nuclear autoantigenic sperm protein is a protein that in humans is encoded by the NASP gene. Multiple isoforms are encoded by transcript variants of this gene.
Prion protein 2 (dublet), also known as PRND, or Doppel protein, is a protein which in humans is encoded by the PRND gene.
Sperm surface protein Sp17 is a protein that in humans is encoded by the SPA17 gene.
Zona pellucida sperm-binding protein 2 is a protein that in humans is encoded by the ZP2 gene.
Outer dense fiber protein 1 is a protein that in humans is encoded by the ODF1 gene.
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A is an enzyme that in humans is encoded by the PDE1A gene.
Serine protease 23 is an enzyme that in humans is encoded by the PRSS23 gene.
Cystatin-8 is a protein that in humans is encoded by the CST8 gene.
Early placenta insulin-like peptide is a protein that in humans is encoded by the INSL4 gene.
Acrosomal protein SP-10 is a protein that in humans is encoded by the ACRV1 gene.
DNA-binding protein RFX2 is a protein that in humans is encoded by the RFX2 gene.
Sperm-associated antigen 8 is a protein that in humans is encoded by the SPAG8 gene.
Calcium-binding tyrosine phosphorylation-regulated protein is a protein that in humans is encoded by the CABYR gene.
Sperm protein associated with the nucleus on the X chromosome A is a protein that in humans is encoded by the SPANXA1 gene.
Centrosomal protein of 57 kDa is a protein that in humans is encoded by the CEP57 gene. It is also known as translokin.
Eppin is a protein that in humans is encoded by the SPINLW1 gene.
CatSper1, is a protein which in humans is encoded by the CATSPER1 gene. CatSper1 is a member of the cation channels of sperm family of protein. The four proteins in this family together form a Ca2+-permeant ion channel specific essential for the correct function of sperm cells.
Cytochrome b5 reductase 2 is an enzyme that in humans is encoded by the CYB5R2 gene.
A disintegrin and metalloprotease 3, or ADAM3, belongs to a family of peptidase proteins referred to as ADAMs. Many of these are solely found in spermatogenic cells, specifically in the anterior portion of capacitated spermatozoa heads. This membrane protein is critical for crucial steps in fertilization such as migration of sperm through the uterus to the oviduct as well as binding to the zona pellucida. Inactivation of ADAM3 is a cause of male infertility.