SPATA2

SPATA2
Identifiers
Aliases	SPATA2 , PD1, PPP1R145, tamo, spermatogenesis associated 2
External IDs	OMIM: 607662 MGI: 2146885 HomoloGene: 4407 GeneCards: SPATA2
Gene location (Human)
Chr.	Chromosome 20 (human)
End	49,915,529 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	167,334,807 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; middle temporal gyrus; ; endothelial cell; ; Brodmann area 23; ; prefrontal cortex; ; Brodmann area 9; ; caudate nucleus; ; inferior olivary nucleus; ; putamen; ; cingulate gyrus;
	Top expressed in
	cerebellar vermis; ; subiculum; ; visual cortex; ; primary motor cortex; ; hippocampus proper; ; cingulate gyrus; ; jejunum; ; piriform cortex; ; secondary oocyte; ; prefrontal cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding ; molecular function ;
Cellular component	cytoplasm ; nucleus ; fibrillar center ;
Biological process	multicellular organism development ; cell differentiation ; spermatogenesis ; regulation of tumor necrosis factor-mediated signaling pathway ; regulation of inflammatory response ; regulation of necroptotic process ; protein K63-linked deubiquitination ; protein linear deubiquitination ; programmed cell death ;
	Sources:Amigo / QuickGO
Orthologs
	9825
	263876
	ENSG00000158480
	ENSMUSG00000047030
	Q9UM82
	Q8K004
	NM_001135773 ; NM_006038
	NM_170756 ; NM_001356523
	NP_001129245 ; NP_006029
	NP_001343452 ; NP_739562
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 18, 2022

Spermatogenesis-associated protein 2 is a protein that in humans is encoded by the SPATA2 gene.^[5]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000158480 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000047030 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: SPATA2 spermatogenesis associated 2".

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID 8889548.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (5): 277–86. doi: 10.1093/dnares/5.5.277 . PMID 9872452.
Graziotto R, Foresta C, Scannapieco P, et al. (1999). "cDNA cloning and characterization of PD1: a novel human testicular protein with different expressions in various testiculopathies". Exp. Cell Res. 248 (2): 620–6. doi:10.1006/excr.1999.4449. PMID 10222154.
Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. Bibcode:2001Natur.414..865D. doi: 10.1038/414865a . PMID 11780052.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Liliana Slongo M, Zotti L, Onisto M (2003). "Cloning and characterization of the promoter region of human spata2 (spermatogenesis-associated protein 2) gene". Biochim. Biophys. Acta. 1625 (2): 192–6. doi:10.1016/s0167-4781(02)00594-8. PMID 12531478.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000158480 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000047030 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SPATA2 spermatogenesis associated 2".

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SPATA2

Related Research Articles

References

Further reading