SPECC1

SPECC1
Identifiers
Aliases	SPECC1 , CYTSB, HCMOGT-1, HCMOGT1, NSP, sperm antigen with calponin homology and coiled-coil domains 1, NSP5
External IDs	OMIM: 608793 MGI: 2442356 HomoloGene: 45157 GeneCards: SPECC1
Gene location (Human)
Chr.	Chromosome 17 (human)
End	20,319,026 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	62,113,839 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; corpus callosum; ; sural nerve; ; globus pallidus; ; internal globus pallidus; ; external globus pallidus; ; substantia nigra; ; stromal cell of endometrium; ; inferior ganglion of vagus nerve; ; monocyte;
	Top expressed in
	blood; ; molar; ; motor neuron; ; superior colliculus; ; inferior colliculus; ; cerebellar cortex; ; anterior horn of spinal cord; ; ascending aorta; ; pontine nuclei; ; cerebellar vermis;
	More reference expression data
	n/a
Orthologs
	92521
	432572
	ENSG00000128487
	ENSMUSG00000042331
	Q5M775
	Q5SXY1
NM_001033553 ; NM_001033554 ; NM_001033555 ; NM_001243438 ; NM_001243439 ;
	NM_152904 ; NM_001386077 ; NM_001386078 ; NM_001386079 ; NM_001386080 ; NM_001386081 ; NM_001386082 ; NM_001386083 ; NM_001386084 ; NM_001386085
	NM_001029936 ; NM_001281818 ; NM_001310526
NP_001028725 ; NP_001028726 ; NP_001028727 ; NP_001230367 ; NP_001230368 ;
	NP_690868
	NP_001025107 ; NP_001268747 ; NP_001297455
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 05, 2023

Cytospin-B is a protein that, in humans, is encoded by the CYTSB gene.^[5]^[6]^[7]^[8]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000128487 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042331 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Sang N, Fath DM, Giordano A (Dec 2004). "A gene highly expressed in tumor cells encodes novel structure proteins". Oncogene. 23 (58): 9438–46. doi:10.1038/sj.onc.1207988. PMC 4518866 . PMID 15602574.
↑ D'Agostino L, Giordano A (Aug 2008). "Possible functional role of NSPs in cancer". Cell Cycle. 7 (12): 1810–27. doi: 10.4161/cc.7.12.6023 . PMID 18763323.
↑ Morerio C, Acquila M, Rosanda C, Rapella A, Dufour C, Locatelli F, Maserati E, Pasquali F, Panarello C (Apr 2004). "HCMOGT-1 is a novel fusion partner to PDGFRB in juvenile myelomonocytic leukemia with t(5;17)(q33;p11.2)". Cancer Res. 64 (8): 2649–51. doi: 10.1158/0008-5472.CAN-03-4026 . PMID 15087372.
↑ "Entrez Gene: SPECC1 sperm antigen with calponin homology and coiled-coil domains 1".

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID 17081983. S2CID 7827573.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316 . PMID 15342556.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol. 22 (6): 707–16. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000128487 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042331 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15602574-5] Sang N, Fath DM, Giordano A (Dec 2004). "A gene highly expressed in tumor cells encodes novel structure proteins". Oncogene. 23 (58): 9438–46. doi:10.1038/sj.onc.1207988. PMC 4518866 . PMID 15602574.

[pmid18763323-6] D'Agostino L, Giordano A (Aug 2008). "Possible functional role of NSPs in cancer". Cell Cycle. 7 (12): 1810–27. doi: 10.4161/cc.7.12.6023 . PMID 18763323.

[pmid15087372-7] Morerio C, Acquila M, Rosanda C, Rapella A, Dufour C, Locatelli F, Maserati E, Pasquali F, Panarello C (Apr 2004). "HCMOGT-1 is a novel fusion partner to PDGFRB in juvenile myelomonocytic leukemia with t(5;17)(q33;p11.2)". Cancer Res. 64 (8): 2649–51. doi: 10.1158/0008-5472.CAN-03-4026 . PMID 15087372.

[entrez-8] "Entrez Gene: SPECC1 sperm antigen with calponin homology and coiled-coil domains 1".

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SPECC1

Related Research Articles

References

Further reading