SPOCK1 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | SPOCK1 , SPOCK, TESTICAN, TIC1, sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1, SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1, SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 602264 MGI: 105371 HomoloGene: 80193 GeneCards: SPOCK1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Testican-1 is a protein that in humans is encoded by the SPOCK1 gene. [5] [6]
This gene encodes the protein core of a seminal plasma proteoglycan containing chondroitin- and heparan-sulfate chains. The protein's function is under research, though it is from the same family of glycoproteins as SPARC. It is thought its similarity to thyropin-type cysteine protease inhibitors suggests its function may be related to protease inhibition. [6]
Agrin is a large proteoglycan whose best-characterised role is in the development of the neuromuscular junction during embryogenesis. Agrin is named based on its involvement in the aggregation of acetylcholine receptors during synaptogenesis. In humans, this protein is encoded by the AGRN gene.
Decorin is a protein that in humans is encoded by the DCN gene.
Osteonectin (ON) also known as secreted protein acidic and rich in cysteine (SPARC) or basement-membrane protein 40 (BM-40) is a protein that in humans is encoded by the SPARC gene.
Phosphatidylethanolamine-binding protein 1 is a protein that in humans is encoded by the PEBP1 gene.
Collagen alpha-2(VI) chain is a protein that in humans is encoded by the COL6A2 gene.
A disintegrin and metalloproteinase with thrombospondin motifs 1 is an enzyme that in humans is encoded by the ADAMTS1 gene.
Serglycin, also known as hematopoietic proteoglycan core protein or secretory granule proteoglycan core protein, is a protein that in humans is encoded by the SRGN gene. It is primarily expressed in hematopoietic cells and endothelial cells, and is the only known intracellular proteoglycan.
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 is an enzyme that in humans is encoded by the B3GAT3 gene.
SPARC-like protein 1, also known as hevin, is a secreted protein with high structural similarity to SPARC. It interacts with the extracellular matrix to create intermediate states of cell adhesion. Due to its dynamic extracellular roles, being implicated in cancer metastasis and inflammation, it is considered a matricellular protein. In humans hevin is encoded by the SPARCL1 gene.
NEDD8-conjugating enzyme Ubc12 is a protein that in humans is encoded by the UBE2M gene.
A disintegrin and metalloproteinase with thrombospondin motifs 9 is an enzyme that in humans is encoded by the ADAMTS9 gene.
Zinc finger protein 267 is a protein that in humans is encoded by the ZNF267 gene.
Protein HEXIM2 is a protein that in humans is encoded by the HEXIM2 gene.
Glypican-5 is a protein that in humans is encoded by the GPC5 gene.
Fetuin-B is a protein that in humans is encoded by the FETUB gene.
Osteomodulin is a protein that in humans is encoded by the OMD gene.
Testican-2 is a protein that in humans is encoded by the SPOCK2 gene.
Chondroitin sulfate proteoglycan 5 is a protein that in humans is encoded by the CSPG5 gene.
Neuronal pentraxin receptor is a protein that in humans is encoded by the NPTXR gene.
Synaptonemal complex protein 1 is a protein involved in the synaptonemal complex during meiosis, that in humans is encoded by the SYCP1 gene.
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: CS1 maint: DOI inactive as of February 2024 (link)