SSR2

Last updated
SSR2
Identifiers
Aliases SSR2 , TLAP, TRAP-BETA, TRAPB, HSD25, signal sequence receptor subunit 2
External IDs OMIM: 600867; MGI: 1913506; HomoloGene: 2369; GeneCards: SSR2; OMA:SSR2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003145

NM_025448

RefSeq (protein)

NP_003136

NP_079724
NP_001343245
NP_001343246
NP_001343247
NP_001343248

Contents

Location (UCSC) Chr 1: 156.01 – 156.02 Mb Chr 3: 88.58 – 88.59 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Translocon-associated protein subunit beta also known as TRAP-beta is a protein that in humans is encoded by the SSR2 gene. [5] [6]

Function

The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23. [6]

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000163479 Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041355 Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Chinen K, Sudo K, Takahashi E, Nakamura Y (Jul 1995). "Isolation and mapping of the human beta-signal sequence receptor gene (SSR2)". Cytogenetics and Cell Genetics. 70 (3–4): 215–7. doi:10.1159/000134036. PMID   7789174.
  6. 1 2 "Entrez Gene: SSR2 signal sequence receptor, beta (translocon-associated protein beta)".

Further reading