STMN3

Last updated
STMN3
Identifiers
Aliases STMN3 , SCLIP, stathmin 3
External IDs OMIM: 608362 MGI: 1277137 HomoloGene: 7528 GeneCards: STMN3
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001276310
NM_015894

NM_009133

RefSeq (protein)

NP_001263239
NP_056978

NP_033159

Location (UCSC)n/a Chr 2: 180.95 – 180.96 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Stathmin-3 is a protein that in humans is encoded by the STMN3 gene. [4] [5] [6]

Contents

Function

The protein encoded by this gene belongs to the stathmin/oncoprotein 18 family of microtubule-destabilizing phosphoproteins. It is similar to the SCG10 protein and is involved in signal transduction and regulation of microtubule dynamics. [6]

Interactions

STMN3 has been shown to interact with TRPC5. [7]

Related Research Articles

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References

  1. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000027581 Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. Ozon S, Byk T, Sobel A (June 1998). "SCLIP: a novel SCG10-like protein of the stathmin family expressed in the nervous system". Journal of Neurochemistry. 70 (6): 2386–96. doi:10.1046/j.1471-4159.1998.70062386.x. PMID   9603203. S2CID   1252160.
  5. Bai C, Connolly B, Metzker ML, Hilliard CA, Liu X, Sandig V, Soderman A, Galloway SM, Liu Q, Austin CP, Caskey CT (February 2000). "Overexpression of M68/DcR3 in human gastrointestinal tract tumors independent of gene amplification and its location in a four-gene cluster". Proceedings of the National Academy of Sciences of the United States of America. 97 (3): 1230–5. Bibcode:2000PNAS...97.1230B. doi: 10.1073/pnas.97.3.1230 . PMC   15578 . PMID   10655513.
  6. 1 2 "Entrez Gene: STMN3 stathmin-like 3".
  7. Greka A, Navarro B, Oancea E, Duggan A, Clapham DE (August 2003). "TRPC5 is a regulator of hippocampal neurite length and growth cone morphology". Nature Neuroscience. 6 (8): 837–45. doi:10.1038/nn1092. PMID   12858178. S2CID   7523946.

Further reading