STOX1

STOX1
Identifiers
Aliases	STOX1 , C10orf24, PEE4, storkhead box 1
External IDs	OMIM: 609397 MGI: 2684909 HomoloGene: 17649 GeneCards: STOX1
Gene location (Human) Chr. Chromosome 10 (human) [1] Band 10q22.1 Start 68,827,531 bp [1] End 68,895,432 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10|10 B4 Start 62,494,822 bp [2] End 62,561,907 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in bronchial epithelial cell amygdala endothelial cell cingulate gyrus nucleus accumbens putamen caudate nucleus Brodmann area 9 right uterine tube hypothalamus Top expressed in spermatocyte otolith organ morula utricle islet of Langerhans olfactory epithelium retinal pigment epithelium spermatid skin of abdomen right lung lobe More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding protein binding Cellular component cytoplasm centrosome nucleoplasm microtubule organizing center cell cortex cytoskeleton nucleus fibrillar center nucleolus cytosol Biological process positive regulation of protein kinase B signaling regulation of transcription, DNA-templated regulation of mitochondrion organization regulation of mitochondrial DNA metabolic process positive regulation of epithelial cell proliferation negative regulation of gene expression transcription, DNA-templated positive regulation of peptidyl-serine phosphorylation positive regulation of cyclin-dependent protein kinase activity cell division regulation of mitochondrial membrane potential positive regulation of gene expression positive regulation of cell cycle positive regulation of peptidyl-threonine phosphorylation positive regulation of cell population proliferation regulation of transcription from RNA polymerase II promoter in response to hypoxia regulation of response to oxidative stress regulation of gene expression inner ear development positive regulation of G2/M transition of mitotic cell cycle cell cycle cellular response to nitrosative stress positive regulation of otic vesicle morphogenesis regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219736 216021 Ensembl ENSG00000165730 ENSMUSG00000036923 UniProt Q6ZVD7 B2RQL2 RefSeq (mRNA) NM_001130159 NM_001130160 NM_001130161 NM_001130162 NM_152709 NM_001033260 NM_001364705 RefSeq (protein) NP_001123631 NP_001123632 NP_001123633 NP_689922 NP_001028432 NP_001351634 Location (UCSC) Chr 10: 68.83 – 68.9 Mb Chr 10: 62.49 – 62.56 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Storkhead box 1 is a protein in humans that is encoded by the STOX1 gene. ^[5]

The protein encoded by this gene may function as a DNA binding protein. Mutations in this gene are associated with pre-eclampsia/eclampsia 4 (PEE4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

References

1. GRCh38: Ensembl release 89: ENSG00000165730 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000036923 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Storkhead box 1" . Retrieved 2013-03-24.