Sapogenin

Last updated September 27, 2025

Sapogenins are aglycones (non-saccharide moieties) of saponins, a large family of natural products. Sapogenins contain steroid or other triterpene frameworks as their key organic feature. Some steroidal sapogenins can serve as a practical starting point for the semisynthesis of particular steroid hormones.

Diosgenin and hecogenin ^[2] are examples of sapogenins.

References

↑ Roland Hardman, Ezekiel Abayomi Sofowora (March 1970). "Isolation and characterization of yamogenin from balanites aegyptiaca". Phytochemistry. 9 (3): 645–649. doi:10.1016/S0031-9422(00)85706-4.
↑ Djerassi, Carl; Martinez, H.; Rosenkranz, G. (1951). "Steroidal Sapogenins. Vii.1Experiments in the Hecogenin Series (Part 1)". The Journal of Organic Chemistry. 16 (2): 303–308. doi:10.1021/jo01142a021.

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[1] Roland Hardman, Ezekiel Abayomi Sofowora (March 1970). "Isolation and characterization of yamogenin from balanites aegyptiaca". Phytochemistry. 9 (3): 645–649. doi:10.1016/S0031-9422(00)85706-4.

[2] Djerassi, Carl; Martinez, H.; Rosenkranz, G. (1951). "Steroidal Sapogenins. Vii.1Experiments in the Hecogenin Series (Part 1)". The Journal of Organic Chemistry. 16 (2): 303–308. doi:10.1021/jo01142a021.

[2]