Sarah Hewlett | |
---|---|
Born | Sarah Elizabeth Hewlett |
Alma mater | St Bartholomew's Hospital University of Bristol |
Known for | Rheumatoid arthritis |
Awards | Fellow of the Royal College of Nursing |
Scientific career | |
Institutions | University of the West of England University of Bristol |
Thesis | Values, disability and personal impact in rheumatoid arthritis (2000) |
Website | people |
Sarah Elizabeth Hewlett OBE is an emeritus Professor of Rheumatology Nursing at the University of the West of England and expert on rheumatoid arthritis (RA). [1] [2] She was appointed an Officer of the Order of the British Empire in the 2019 Birthday Honours.
Hewlett studied nursing at St Bartholomew's Hospital and graduated in 1975. [3] She spent five years as a senior sister in a neurosurgical unit before becoming a clinical researcher. [3] She was supported by the Arthritis Research Campaign (now Versus Arthritis). [4] She studied health care ethics at the University of Wales, investigating the ethics of informed consent. [3] She earned a PhD at the University of Bristol in 2000, [5] where she studied the impact of disability in rheumatoid arthritis. [3]
Hewlett spent the early part of her nursing career in clinical care. [6] She then moved into research, where worked on rheumatology care, education and research. She collaborated with the University Hospitals Bristol NHS Foundation Trust. Hewlett identified that patients suffering from rheumatoid arthritis (RA) consider fatigue as a significant and often overlooked problem. She estimated that up to 98% of people who suffer from RA experience fatigue. [7] She noticed that whilst fatigue makes the symptoms worse for patients with multiple sclerosis, rheumatoid arthritis makes fatigue worse. [8] She described flares of rheumatoid arthritis as "duvet and chocolate days". [9] Hewlett evaluated the provisions nurses had for treating fatigue, and found that they had limited ways to measure and manage fatigue. [8] Hewlett went on to develop a protocol to evaluate fatigue. She then ensured that it was evaluated in every rheumatoid arthritis trial. [10] In 2007 she was the first person to be named a Chair in Rheumatology Nursing at the University of the West of England. [4]
The protocol developed by Hewlett, the Bristol RA Fatigue Scales (BRAFs), can be used to evaluate the severity of disease, and have been translated into 36 languages. [11] [12] [13] [14] Once she had developed a metric to measure fatigue, Hewlett developed interventions to manage fatigue, including the use of cognitive behavioural therapy (CBT). [10] [15] Her research into the design and testing of CBT interventions was supported by the National Institute for Health Research. [16] CBT was shown to reduce the impact and severity of fatigue in patients with RA, and adopted by occupational therapists in Scotland and British Columbia. [10]
Hewlett contributed to the Oxford Textbook of Rheumatology. [17]
Her awards and honours include:
Arthritis is a term often used to mean any disorder that affects joints. Symptoms generally include joint pain and stiffness. Other symptoms may include redness, warmth, swelling, and decreased range of motion of the affected joints. In some types of arthritis, other organs are also affected. Onset can be gradual or sudden.
Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest. Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body. The disease may also affect other parts of the body, including skin, eyes, lungs, heart, nerves and blood. This may result in a low red blood cell count, inflammation around the lungs, and inflammation around the heart. Fever and low energy may also be present. Often, symptoms come on gradually over weeks to months.
Sjögren syndrome or Sjögren's syndrome is a long-term autoimmune disease that affects the body's moisture-producing glands, and often seriously affects other organ systems, such as the lungs, kidneys, and nervous system. Primary symptoms are dryness, pain and fatigue. Other symptoms can include dry skin, vaginal dryness, a chronic cough, numbness in the arms and legs, feeling tired, muscle and joint pains, and thyroid problems. Those affected are also at an increased risk (15%) of lymphoma.
The University of the West of England, Bristol is a public research university, located in and around Bristol, England. Founded in 1970 as the Bristol Polytechnic, which received university status in 1992 and became the University of the West of England, Bristol.
Fibromyalgia (FM) is a medical condition defined by the presence of chronic widespread pain, fatigue, waking unrefreshed, cognitive symptoms, lower abdominal pain or cramps, and depression. Other symptoms include insomnia and a general hypersensitivity.
Juvenile idiopathic arthritis (JIA) is the most common, chronic rheumatic disease of childhood, affecting approximately one per 1,000 children. Juvenile, in this context, refers to disease onset before 16 years of age, while idiopathic refers to a condition with no defined cause, and arthritis is inflammation within the joint.
Felty's syndrome (FS), also called Felty syndrome, is rare autoimmune disease characterized by the triad of rheumatoid arthritis, enlargement of the spleen and low neutrophil count. The condition is more common in those aged 50–70 years, specifically more prevalent in females than males, and more so in Caucasians than those of African descent. It is a deforming disease that causes many complications for the individual.
A nurse-led clinic is any outpatient clinic that is run or managed by registered nurses, usually nurse practitioners or Clinical Nurse Specialists in the UK. Nurse-led clinics have assumed distinct roles over the years, and examples exist within hospital outpatient departments, public health clinics and independent practice environments.
Allen Caruthers Steere is a professor of rheumatology at Harvard University and previously at Tufts University and Yale University. Steere and his mentor, Stephen Malawista of Yale University, are credited with discovering and naming Lyme disease, and he has published almost 300 scholarly articles on Lyme disease during his more than 40 years of studies of this infection. At a ceremony in Hartford, Connecticut in 1998, Governor John G. Rowland declared September 24 to be "Allen C. Steere Day."
Anti-citrullinated protein antibodies (ACPAs) are autoantibodies that are directed against peptides and proteins that are citrullinated. They are present in the majority of patients with rheumatoid arthritis. Clinically, cyclic citrullinated peptides (CCP) are frequently used to detect these antibodies in patient serum or plasma.
ACR score is a scale to measure change in rheumatoid arthritis symptoms. It is named after the American College of Rheumatology. The ACR score is more often used in clinical trials than in doctor patient-relationships, as it allows a common standard between researchers.
Sarilumab, sold under the brand name Kevzara, is a human monoclonal antibody medication against the interleukin-6 receptor. Regeneron Pharmaceuticals and Sanofi developed the drug for the treatment of rheumatoid arthritis (RA), for which it received US FDA approval on 22 May 2017 and European Medicines Agency approval on 23 June 2017.
Patient satisfaction is a measure of the extent to which a patient is content with the health care which they received from their health care provider.
Upadacitinib, sold under the brand name Rinvoq, is a Janus kinase (JAK) inhibitor medication for the treatment of moderately to severely active rheumatoid arthritis and psoriatic arthritis in adults where methotrexate did not work well or could not be tolerated. It was approved for medical use in the United States and in the European Union in 2019, and was developed by the biotech company AbbVie.
Sarah Elizabeth Lamb is the Pro-Vice-Chancellor and Executive Dean of the Faculty of Health and Life Sciences at the University of Exeter, and the Mireille Gillings Professor for Health Innovation. She is also an Honorary Departmental Professor at the Nuffield Department of Medicine, University of Oxford and the Director of the Oxford Clinical Trials Research Unit.
Paul-Peter Tak is an immunologist and academic specialising in the fields of rheumatology and immunology. In addition to academic research, he served as an executive of several pharmaceutical companies.
Michelle Leech FRACP is the Deputy Dean of Medicine at Monash University and an academic clinician-scientist. Leech oversees the delivery of the Monash medical program and maintains an active research profile and clinical practice as a rheumatologist.
An antiarthritic is any member of the group of drugs used to relieve or prevent arthritic symptoms, such as joint pain and joint stiffness. Depending on the antiarthritic drug class, it can be responsible for managing pain, reducing inflammation and/or acting as an immunosuppressant. These drugs are typically given orally, topically or through administration by injection. The choice of antiarthritic medication is often determined by the type/nature of arthritis, the severity of symptoms as well as other factors, such as the tolerability of side effects.
Sarah Onuora is a Canadian rheumatologist and the chief editor of Nature Reviews Rheumatology.