Scoparone

Scoparone
Names
	Preferred IUPAC name 6,7-Dimethoxy-2H-1-benzopyran-2-one
	Other names 6,7-Dimethoxycoumarin; 6,7-Dimethylesculetin; Esculetin dimethyl ether; Scoparon; Escoparone
Identifiers
CAS Number	120-08-1 ;
3D model (JSmol)	Interactive image ;
ChEBI	CHEBI:9055 ;
ChemSpider	8110 ;
ECHA InfoCard	100.003.972
PubChem CID	8417 ;
UNII	H5841PDT4Y ;
CompTox Dashboard (EPA)	DTXSID10152640 ;
	InChI InChI=1S/C11H10O4/c1-13-9-5-7-3-4-11(12)15-8(7)6-10(9)14-2/h3-6H,1-2H3 Key: GUAFOGOEJLSQBT-UHFFFAOYSA-N; InChI=1/C11H10O4/c1-13-9-5-7-3-4-11(12)15-8(7)6-10(9)14-2/h3-6H,1-2H3 Key: GUAFOGOEJLSQBT-UHFFFAOYAO;
	SMILES O=C/2Oc1cc(OC)c(OC)cc1\C=C\2;
Properties
Chemical formula	C11H10O4
Molar mass	206.197 g·mol−1
Melting point	143 to 145 °C (289 to 293 °F; 416 to 418 K)
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Last updated February 23, 2025

Scoparone is a natural organic compound with the molecular formula C₁₁H₁₀O₄. It is found in the Chinese herb Artemisia scoparia and has been studied for its potential pharmacological properties including immunosuppression and vasorelaxation.^[2]^[3]

References

↑ "6,7-Dimethoxycoumarin". Sigma-Aldrich.
↑ Huei-Chen, Huang; Shu-Hsun, Chu; Pei-Dawn Lee Chao, PD (1991). "Vasorelaxants from Chinese herbs, emodin and scoparone, possess immunosuppressive properties". European Journal of Pharmacology. 198 (2–3): 211–3. doi:10.1016/0014-2999(91)90624-Y. PMID 1830846.
↑ Huang, Huei-Chen; Lee, Chai-Rong; Weng, Yu-I; Lee, Ming-Chih; Lee, Yuan-Teh (1992). "Vasodilator effect of scoparone (6,7-dimethoxycoumarin) from a Chinese herb". European Journal of Pharmacology. 218 (1): 123–8. doi:10.1016/0014-2999(92)90155-W. PMID 1327821.

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[1] "6,7-Dimethoxycoumarin". Sigma-Aldrich.

[2] Huei-Chen, Huang; Shu-Hsun, Chu; Pei-Dawn Lee Chao, PD (1991). "Vasorelaxants from Chinese herbs, emodin and scoparone, possess immunosuppressive properties". European Journal of Pharmacology. 198 (2–3): 211–3. doi:10.1016/0014-2999(91)90624-Y. PMID 1830846.

[3] Huang, Huei-Chen; Lee, Chai-Rong; Weng, Yu-I; Lee, Ming-Chih; Lee, Yuan-Teh (1992). "Vasodilator effect of scoparone (6,7-dimethoxycoumarin) from a Chinese herb". European Journal of Pharmacology. 218 (1): 123–8. doi:10.1016/0014-2999(92)90155-W. PMID 1327821.

[1]

[2]

[3]

Names

Preferred IUPAC name 6,7-Dimethoxy-2H-1-benzopyran-2-one
Other names 6,7-Dimethoxycoumarin; 6,7-Dimethylesculetin; Esculetin dimethyl ether; Scoparon; Escoparone
Identifiers
CAS Number	120-08-1 ^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:9055
ChemSpider	8110
ECHA InfoCard	100.003.972
PubChem CID	8417
UNII	H5841PDT4Y ^Y
CompTox Dashboard (EPA)	DTXSID10152640
InChI InChI=1S/C11H10O4/c1-13-9-5-7-3-4-11(12)15-8(7)6-10(9)14-2/h3-6H,1-2H3 Key: GUAFOGOEJLSQBT-UHFFFAOYSA-N InChI=1/C11H10O4/c1-13-9-5-7-3-4-11(12)15-8(7)6-10(9)14-2/h3-6H,1-2H3 Key: GUAFOGOEJLSQBT-UHFFFAOYAO
SMILES O=C/2Oc1cc(OC)c(OC)cc1\C=C\2
Properties
Chemical formula	C₁₁H₁₀O₄
Molar mass	206.197 g·mol⁻¹
Melting point	143 to 145 °C (289 to 293 °F; 416 to 418 K)^[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references