Sebox homeobox

SEBOX
Identifiers
Aliases	SEBOX , OG-9, OG9, OG9X, Sebox homeobox
External IDs	OMIM: 610975 MGI: 108012 HomoloGene: 32052 GeneCards: SEBOX
Gene location (Human)
Chr.	Chromosome 17 (human)
End	28,365,199 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	78,395,907 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; skeletal muscle tissue; ; blood; ; monocyte; ; duodenum; ; Right adrenal gland; ; prefrontal cortex; ; smooth muscle tissue; ; islet of Langerhans; ; placenta;
	Top expressed in
	secondary oocyte; ; morula; ; submandibular gland; ; urethra; ; ovarian follicle; ; granular layer; ; Region IV of hippocampus proper; ; triceps brachii muscle; ; lip; ; Region I of hippocampus proper;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding ; molecular function ;
Cellular component	nucleus ; cellular component ;
Biological process	multicellular organism development ; cell differentiation ; regulation of transcription, DNA-templated ; transcription, DNA-templated ; biological process ; embryo development ending in birth or egg hatching ; oogenesis ;
	Sources:Amigo / QuickGO
Orthologs
	645832
	18292
	ENSG00000274529
	ENSMUSG00000001103
	Q9HB31
	P70368
	NM_001083896 ; NM_001080837
	NM_008759
	NP_001074306
	NP_032785
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 14, 2022

SEBOX homeobox is a protein that in humans is encoded by the SEBOX gene.^[5] Sebox homeobox has a 92% similarity to genes found within rhesus macaque, or the rhesus monkey. It is thought that this is what causes the reddened glutius maximus coloring. If the protein is turned on within a person, it may cause discoloring in the human rear.

Function

Homeodomain proteins, such as SEBOX, play a key role in coordinating gene expression during development.^[6]

Related Research Articles

Homeobox protein Hox-A7 is a protein that in humans is encoded by the HOXA7 gene.

Homeobox protein Hox-C13 is a protein that in humans is encoded by the HOXC13 gene.

Homeobox protein Hox-C9 is a protein that in humans is encoded by the HOXC9 gene.

Homeobox protein Hox-D1 is a protein that in humans is encoded by the HOXD1 gene.

Homeobox protein Hox-D8 is a protein that in humans is encoded by the HOXD8 gene.

Homeobox protein Hox-C11 is a protein that in humans is encoded by the HOXC11 gene.

Homeobox protein Nkx-2.3 is a protein that in humans is encoded by the NKX2-3 gene.

Paired mesoderm homeobox protein 2 is a protein that in humans is encoded by the PRRX2 gene.

Homeobox protein SIX2 is a protein that in humans is encoded by the SIX2 gene.

Homeobox protein Hox-A2 is a protein that in humans is encoded by the HOXA2 gene.

Homeobox protein Nkx-6.2 is a protein that in humans is encoded by the NKX6-2 gene.

Homeobox protein DBX1, also known as developing brain homeobox protein 1, is a protein that in humans is encoded by the DBX1 gene. The DBX1 gene is a transcription factor gene that is pivotal in interneuron differentiation in the ventral spinal cord.

Homeobox protein DBX2, also known as developing brain homeobox protein 2, is a protein that in humans is encoded by the DBX2 gene. DBX2 plays an important role in the development of the central nervous system, specifically in the development of the neural tube and brain. DBX2 is located on chromosome 12 and is approximately 36,000 base pairs long. DBX2 is predicted to enable DNA-binding transcription activity as well as being involved in the regulation of transcription by RNA polymerase II.

Iroquois-class homeodomain protein IRX-2, also known as Iroquois homeobox protein 2, is a protein that in humans is encoded by the IRX2 gene.

Iroquois-class homeodomain protein IRX-4, also known as Iroquois homeobox protein 4, is a protein that in humans is encoded by the IRX4 gene.

Iroquois-class homeodomain protein IRX-6, also known as Iroquois homeobox protein 6, is a protein that in humans is encoded by the IRX6 gene.

Homeobox protein Mohawk, also known as iroquois homeobox protein-like 1, is a protein that in humans is encoded by the MKX gene. MKX is a member of an Iroquois (IRX) family-related class of 'three-amino acid loop extension' (TALE) atypical homeobox proteins characterized by 3 additional amino acids in the loop region between helix I and helix II of the homeodomain.

Short-stature homeobox 2, also known as homeobox protein Og12X or paired-related homeobox protein SHOT, is a protein that in humans is encoded by the SHOX2 gene.

Homeobox C12 is a protein that in humans is encoded by the HOXC12 gene.

LIM homeobox 9 is a protein that in humans is encoded by the LHX9 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000274529 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000001103 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: SEBOX homeobox".
↑ Cinquanta M, Rovescalli AC, Kozak CA, Nirenberg M (2000). "Mouse Sebox homeobox gene expression in skin, brain, oocytes, and two-cell embryos". Proc. Natl. Acad. Sci. U.S.A. 97 (16): 8904–9. Bibcode:2000PNAS...97.8904C. doi: 10.1073/pnas.97.16.8904 . PMC 16794 . PMID 10922053.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000274529 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000001103 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: SEBOX homeobox".

[pmid10922053-6] Cinquanta M, Rovescalli AC, Kozak CA, Nirenberg M (2000). "Mouse Sebox homeobox gene expression in skin, brain, oocytes, and two-cell embryos". Proc. Natl. Acad. Sci. U.S.A. 97 (16): 8904–9. Bibcode:2000PNAS...97.8904C. doi: 10.1073/pnas.97.16.8904 . PMC 16794 . PMID 10922053.

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