Shelli Avenevoli | |
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| Alma mater | Temple University |
| Scientific career | |
| Fields | Epidemiology |
| Institutions | National Institute of Mental Health |
| Thesis | The continuity of depression from childhood to adolescence (1998) |
| Doctoral advisor | Laurence Steinberg |
Shelli Avenevoli is an American epidemiologist working as acting director [1] of the National Institute of Mental Health. She is a co-investigator on the National Comorbidity Study.
Avenevoli received her Ph.D. in Developmental Psychology from Temple University. [2] Her 1998 dissertation was titled The continuity of depression from childhood to adolescence. Avenevoli's doctoral advisor was Laurence Steinberg. [3]
Avenevoli completed an National Institute of Mental Health (NIMH)-funded postdoctoral fellowship in psychiatric epidemiology at Yale School of Medicine. [2]
In 2001, Avenevoli joined the NIMH intramural research program as a staff scientist in the Section of Developmental Genetic Epidemiology of the Mood and Anxiety Disorders Program. In 2005, she moved to the NIMH division of extramural research as chief of the Emotion, Mood, and Depressive Disorders Program. In 2008, Avenevoli became chief of the Developmental Trajectories of Mental Disorders Branch. [2] In this role, she developed NIMH’s translational neurodevelopmental research portfolio and a research program on bipolar disorder and early, chronic irritability in children. [4] Avenevoli is involved in NIMH efforts, including revising the strategic plan, re-defining the Institute’s approach to supporting research in neurodevelopment and bipolar disorder, and serving as a liaison to other agencies for special initiatives. Avenevoli is acting director of NIMH. [1] She is a co-investigator on the National Comorbidity Study. [4]
Bipolar I disorder is a type of bipolar spectrum disorder characterized by the occurrence of at least one manic episode, with or without mixed or psychotic features. Most people also, at other times, have one or more depressive episodes. Typically, these manic episodes can last at least 7 days for most of each day to the extent that the individual may need medical attention, while the depressive episodes last at least 2 weeks.
The National Institute of Mental Health (NIMH) is one of 27 institutes and centers that make up the National Institutes of Health (NIH). The NIH, in turn, is an agency of the United States Department of Health and Human Services and is the primary agency of the United States government responsible for biomedical and health-related research.
Psychopathology is the study of mental illness. It includes the signs and symptoms of all mental disorders. The field includes abnormal cognition, maladaptive behavior, and experiences which differ according to social norms. This discipline is an in-depth look into symptoms, behaviors, causes, course, development, categorization, treatments, strategies, and more.
Depression is a mental state of low mood and aversion to activity. It affects about 3.5% of the global population, or about 280 million people of all ages. Depression affects a person's thoughts, behavior, feelings, and sense of well-being. Experiences that would normally bring a person pleasure or joy gives reduced pleasure or joy, and the afflicted person often experiences a loss of motivation or interest in those activities.
Bipolar disorder in children, or pediatric bipolar disorder (PBD), is a rare mental disorder in children and adolescents. The diagnosis of bipolar disorder in children has been heavily debated for many reasons including the potential harmful effects of adult bipolar medication use for children. PBD is similar to bipolar disorder (BD) in adults, and has been proposed as an explanation for periods of extreme shifts in mood called mood episodes. These shifts alternate between periods of depressed or irritable moods and periods of abnormally elevated moods called manic or hypomanic episodes. Mixed mood episodes can occur when a child or adolescent with PBD experiences depressive and manic symptoms simultaneously. Mood episodes of children and adolescents with PBD are different from general shifts in mood experienced by children and adolescents because mood episodes last for long periods of time and cause severe disruptions to an individual's life. There are three known forms of PBD: Bipolar I, Bipolar II, and Bipolar Not Otherwise Specified (NOS). The average age of onset of PBD remains unclear, but reported age of onset ranges from 5 years of age to 19 years of age. PBD is typically more severe and has a poorer prognosis than bipolar disorder with onset in late-adolescence or adulthood.
Marian Radke-Yarrow was an American child psychologist known for studying topics such as prejudice, altruism, and depression in children. She worked in academia in the early years after completing graduate school, and then she became a National Institute of Mental Health (NIMH) researcher who observed child behavior and parent-child interactions.
Joseph Biederman was an American academic psychiatrist. He was Chief of the Clinical and Research Programs in Pediatric Psychopharmacology and Adult ADHD at the Massachusetts General Hospital and a professor of psychiatry at Harvard Medical School.
Major depressive disorder, often simply referred to as depression, is a mental disorder characterized by prolonged unhappiness or irritability. It is accompanied by a constellation of somatic and cognitive signs and symptoms such as fatigue, apathy, sleep problems, loss of appetite, loss of engagement, low self-regard/worthlessness, difficulty concentrating or indecisiveness, or recurrent thoughts of death or suicide.
Thomas Roland Insel is an American neuroscientist, psychiatrist, entrepreneur, and author who led the National Institute of Mental Health (NIMH) from 2002 until November 2015. Prior to becoming Director of NIMH, he was the founding Director of the Center for Behavioral Neuroscience at Emory University in Atlanta, Georgia. He is best known for research on oxytocin and vasopressin, two peptide hormones implicated in complex social behaviors, such as parental care and attachment. He announced on Sept. 15, 2015, that he was resigning as the director of the NIMH to join the Life Science division of Google X. On May 8, 2017, CNBC reported that he had left Verily Life Sciences. Insel is a Co-founder with Richard Klausner and Paul Dagum of a digital mental health company named "Mindstrong," a Bay-area startup. He has also co-founded Humanest Care, NeuraWell Therapeutics, and MindSite News and is a member of the scientific advisory board for Compass Pathways, a company that is developing the psychedelic drug psilocybin to treat depression and other mental health disorders. His book, Healing: Our Path from Mental Illness to Mental Health was published by Penguin Random House in February, 2022.
Susan Swedo is a researcher in the field of pediatrics and neuropsychiatry. Beginning in 1998, she was Chief of the Pediatrics & Developmental Neuroscience Branch at the US National Institute of Mental Health. In 1994, Swedo was lead author on a paper describing pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS), a controversial hypothesis proposing a link between Group A streptococcal infection in children and some rapid-onset cases of obsessive-compulsive disorder (OCD) or tic disorders such as Tourette syndrome. Swedo retired from the NIH in 2019, and serves on the PANDAS Physician Network.
Cyclothymia, also known as cyclothymic disorder, psychothemia / psychothymia, bipolar III, affective personality disorder and cyclothymic personality disorder, is a mental and behavioural disorder that involves numerous periods of symptoms of depression and periods of symptoms of elevated mood. These symptoms, however, are not sufficient to indicate a major depressive episode or a manic episode. Symptoms must last for more than one year in children and two years in adults.
Disruptive mood dysregulation disorder (DMDD) is a mental disorder in children and adolescents characterized by a persistently irritable or angry mood and frequent temper outbursts that are disproportionate to the situation and significantly more severe than the typical reaction of same-aged peers. DMDD was added to the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) as a type of depressive disorder diagnosis for youths. The symptoms of DMDD resemble many other disorders, thus a differential includes attention-deficit/hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), anxiety disorders, and childhood bipolar disorder, intermittent explosive disorder (IED), major depressive disorder (MDD), and conduct disorder.
Lori Altshuler was a professor at the University of California, Los Angeles (UCLA) Department of Psychiatry and Biobehavioral Sciences and held the Julia S. Gouw Endowed Chair for Mood Disorders. Altshuler was the Director of the UCLA Mood Disorders Research Program and the UCLA Women's Life Center, each being part of the Neuropsychiatric Hospital at UCLA.
Kathleen Ries Merikangas is the Chief of the Genetic Epidemiology Research Branch in the Intramural Research Program at the National Institute of Mental Health (NIMH) and an adjunct professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health. She has published more than 300 papers, and is best known for her work in adolescent mental disorders.
Della Marie Hann is an American psychologist and research administrator serving as the associate director for extramural research at the Eunice Kennedy Shriver National Institute of Child Health and Human Development.
Mauricio Tohen is a Mexican American research psychiatrist, Distinguished Professor, and Chairman of the Department of Psychiatry & Behavioral Sciences at the University of New Mexico. Tohen's research has focused on the epidemiology, outcome, and treatment of bipolar and psychotic disorders, and is especially known for innovating the design of clinical trials and the criteria to determine outcome in such diseases. Tohen has edited several books on his specialties. His social awareness has been noted in the promotion of programs to improve mental health care in areas such as substance abuse, bipolar disorder and schizophrenia.
LeShawndra N. Price is an American psychologist specialized in mental health and health disparities research. She is the director of the office of research training and special programs at the National Institute of Allergy and Infectious Diseases.
Katie A. McLaughlin is an American clinical psychologist and expert on how stress, trauma, and other adverse events, such as natural disorders or pandemics, affect behavioral and brain development during childhood and adolescence. McLaughlin is a Professor of Psychology at Harvard University.
Ellen Leibenluft is an American psychiatrist and physician-scientist researching the brain mechanisms mediating bipolar disorder and severe irritability in children and adolescents. She is a senior investigator and chief of the mood dysregulation and neuroscience section at the National Institute of Mental Health.
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This article incorporates text from this source, which is in the public domain . This article incorporates text from this source, which is in the public domain . This article incorporates public domain material from websites or documents of the National Institutes of Health.
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