South Carolina Highway 6 (SC 6) is a 116.092-mile (186.832 km) primary state highway in the U.S. state of South Carolina. It extends from US 76 in Ballentine to US 52/SC 6 Truck in Moncks Corner. It uniquely links all three of the major hydropower projects in South Carolina: Lake Murray, Lake Marion, and Lake Moultrie.
South Carolina Highway 34 (SC 34) is a 185.930-mile (299.225 km) primary state highway in the U.S. state of South Carolina. As one of the longer state highways, it traverses the state east–west from Greenwood to Dillon, connecting the cities of Newberry, Winnsboro, Camden, Bishopville and Darlington.
South Carolina Highway 200 (SC 200) is a 42.780-mile (68.848 km) primary state highway in the U.S. state of South Carolina. The highway travels more in a north–south direction, despite being signed as east–west. It connects the cities of Winnsboro, Great Falls, and Lancaster.
South Carolina Highway 161 (SC 161) is a 28.910-mile (46.526 km) primary state highway in the U.S. state of South Carolina. It connects the cities of Rock Hill, York, and Kings Mountain, North Carolina.
South Carolina Highway 4 (SC 4) is a primary 54.430-mile-long (87.597 km) state highway in the southern part of the U.S. state of South Carolina. The highway connects Aiken and Orangeburg, via Springfield and Neeses.
Several special routes of U.S. Route 21 (US 21) exist. In order from south to north, they are as follows.
South Carolina Highway 19 (SC 19) is a 28.750-mile (46.269 km) primary state highway in the U.S. state of South Carolina. It connects Aiken directly with the Savannah River Site and Edgefield via U.S. Route 25 (US 25).
South Carolina Highway 23 (SC 23) is a 47.060-mile (75.736 km) primary state highway in the U.S. state of South Carolina. It serves to connect Edgefield and Batesburg-Leesville with Columbia via U.S. Route 1 (US 1).
South Carolina Highway 97 (SC 97) is a 89.800-mile (144.519 km) state highway in the U.S. state of South Carolina. The highway connects Camden, Great Falls, Chester, and Hickory Grove.
South Carolina Highway 203 (SC 203) is a 7.750-mile-long (12.472 km) state highway in the U.S. state of South Carolina. The highway connects Abbeville and rural areas of Abbeville County.
South Carolina Highway 213 (SC 213) is a 21.380-mile-long (34.408 km) state highway in the U.S. state of South Carolina. The highway travels through mostly rural areas of Newberry and Fairfield counties. It also connects Jenkinsville and the Winnsboro area.
South Carolina Highway 252 (SC 252) is a 35.711-mile-long (57.471 km) state highway in the U.S. state of South Carolina. The highway connects the Anderson and Laurens areas with Honea Path and Ware Shoals. It has a unique feature in that it intersects U.S. Route 76 (US 76) three times along its length.
South Carolina Highway 292 (SC 292) is a 13.640-mile-long (21.951 km) state highway in the U.S. state of South Carolina. The highway connects Duncan and the Inman area, via Lyman.
South Carolina Highway 332 (SC 332) is a 18.070-mile (29.081 km) state highway in the U.S. state of South Carolina. The highway travels through mostly rural areas of Orangeburg County.
South Carolina Highway 389 (SC 389) is a 13.730-mile-long (22.096 km) state highway in the U.S. state of South Carolina. The highway connects Neeses and Perry.
South Carolina Highway 453 (SC 453) is a 14.930-mile-long (24.028 km) state highway in the U.S. state of South Carolina. The highway connects Harleyville and Eutawville, via Holly Hill.
South Carolina Highway 764 (SC 764) is a 8.950-mile-long (14.404 km) primary state highway in the U.S. state of South Carolina. The highway connects rural areas of Richland County with Eastover.
South Carolina Highway 769 (SC 769) is a 9.590-mile-long (15.434 km) state highway in the U.S. state of South Carolina. The highway connects Gadsden and Horrell Hill.
South Carolina Highway 118 (SC 118) is a 13.180-mile (21.211 km) state highway in the U.S. state of South Carolina. The highway, in combination with SC 302, create a non-freeway beltway around downtown Aiken. The highway is officially designated on the road around the southwestern, western, and northern sides of the city. The southeastern portion of the beltway is part of SC 302, which is the termini of SC 118.
South Carolina Highway 302 (SC 302) is an 66.200-mile-long (106.539 km) state highway in the U.S. state of South Carolina. The highway travels through mostly rural areas of Aiken and Lexington counties and connects the Aiken with the Columbia metropolitan areas, via Wagener and Pelion.