Organ transplantation is a medical procedure in which an organ is removed from one body and placed in the body of a recipient, to replace a damaged or missing organ. The donor and recipient may be at the same location, or organs may be transported from a donor site to another location. Organs and/or tissues that are transplanted within the same person's body are called autografts. Transplants that are recently performed between two subjects of the same species are called allografts. Allografts can either be from a living or cadaveric source.
A head transplant or full body transplant is an experimental surgical operation involving the grafting of one organism's head onto the body of another. In many experiments, the recipient's head has not been removed, but in others it has been. Experimentation in animals began in the early 1900s. As of 2025, no lasting successes have been achieved.
A crash test dummy, or simply dummy, is a full-scale anthropomorphic test device (ATD) that simulates the dimensions, weight proportions and articulation of the human body during a traffic collision. Dummies are used by researchers, automobile and aircraft manufacturers to predict the injuries a person might sustain in a crash. Modern dummies are usually instrumented to record data such as velocity of impact, crushing force, bending, folding, or torque of the body, and deceleration rates during a collision.
The history of anatomy in the 19th century saw anatomists largely finalise and systematise the descriptive human anatomy of the previous century. The discipline also progressed to establish growing sources of knowledge in histology and developmental biology, not only of humans but also of animals.
A morgue or mortuary is a place used for the storage of human corpses awaiting identification (ID), removal for autopsy, respectful burial, cremation or other methods of disposal. In modern times, corpses have customarily been refrigerated to delay decomposition.
Joseph Edward Murray was an American plastic surgeon who is known as the "father of transplantation" for major milestones in the field of transplantation, including performing the first successful human kidney transplant, defining brain death, the organization of the first international conference on human kidney transplants and founding of the National Kidney Registry, the forerunner of the current United Network Of Organ Sharing (UNOS). By 2013, more than one million patients are estimated to have benefitted from organ transplantation around the world.
Kidney transplant or renal transplant is the organ transplant of a kidney into a patient with end-stage kidney disease (ESRD). Kidney transplant is typically classified as deceased-donor or living-donor transplantation depending on the source of the donor organ. Living-donor kidney transplants are further characterized as genetically related (living-related) or non-related (living-unrelated) transplants, depending on whether a biological relationship exists between the donor and recipient. The first successful kidney transplant was performed in 1954 by a team including Joseph Murray, the recipient's surgeon, and Hartwell Harrison, surgeon for the donor. Murray was awarded a Nobel Prize in Physiology or Medicine in 1990 for this and other work. In 2018, an estimated 95,479 kidney transplants were performed worldwide, 36% of which came from living donors.
Mary Roach is an American author specializing in popular science and humor. She has published seven New York Times bestsellers: Stiff: The Curious Lives of Human Cadavers (2003), Spook: Science Tackles the Afterlife (2005), Bonk: The Curious Coupling of Science and Sex (2008), Packing for Mars: The Curious Science of Life in the Void (2010), Gulp: Adventures on the Alimentary Canal (2013), Grunt: The Curious Science of Humans at War (2016), and Fuzz: When Nature Breaks the Law (2021).
Caroline Paul is an American writer of fiction and non-fiction.
A mellified man, also known as a human mummy confection, was a legendary medicinal substance created by steeping a human cadaver in honey. The concoction is detailed in Chinese medical sources, including the Bencao Gangmu of the 16th century. Relying on a second-hand account, the text reports a story that some elderly men in Arabia, nearing the end of their lives, would submit themselves to a process of mummification in honey to create a healing confection.
A cadaver, often known as a corpse, is a dead human body. Cadavers are used by medical students, physicians and other scientists to study anatomy, identify disease sites, determine causes of death, and provide tissue to repair a defect in a living human being. Students in medical school study and dissect cadavers as a part of their education. Others who study cadavers include archaeologists and arts students. In addition, a cadaver may be used in the development and evaluation of surgical instruments.
Biomedical Tissue Services (BTS) was a Fort Lee, New Jersey, human tissue recovery firm that was shut down by the U.S. Food and Drug Administration (FDA) on October 8, 2005, after its president, Michael Mastromarino, and three other employees were charged with illegally harvesting human bones, organs, tissue and other cadaver parts from individuals awaiting cremation, for forging numerous consent forms, and for selling the illegally obtained body parts to medical companies without consent of their families.
Out of position (OOP), in crash testing and car accident medical literature, indicates a passenger position which is not the normal upright and forward-facing position. For example, a common case observed in crashes is the position of an occupant when reaching for the car radio, or panic braking in unbelted passengers. The concept is of interest because small changes in a passenger's position can have profound effects on the actual kinematic response, especially in rear impacts, as shown both in practical testing and theoretical models.
Bonk: The Curious Coupling of Science and Sex is a 2008 book by American popular science writer Mary Roach. It follows the winding history of science and its exploration of human sexuality, going back as far as Aristotle and finally ending with recent discoveries about the origination and anatomy of the female orgasm. Throughout, Mary Roach provides a humorous and often very personal view—both as a participant and observer—of humans, scientists, animals, and sex machines. Of the book's numerous accounts, Roach discusses artificial insemination of sows in Denmark, the history of sex machines, and provides commentary on Alfred Kinsey's notorious attic sex experiments. Her footnotes provide additional humor: as in a sentence that includes several DSM diagnoses listed as acronyms, she adds, "And from HAFD ". In the book, Roach describes a session in which she and Ed, her husband, volunteer to have sex while being recorded by a groundbreaking 4D ultrasound, in the interests of science. A doctor looks on during the experiment, making suggestions, and finally telling Ed that he "may ejaculate now".
A beating heart cadaver is a body that is pronounced dead in all medical and legal definitions, connected to a medical ventilator, and retains cardio-pulmonary functions. This keeps the organs of the body, including the heart, functioning and alive. As a result, the period of time in which the organs may be used for transplantation is extended. The heart contains pacemaker cells that will cause it to continue beating even when a patient is brain-dead. Other organs in the body do not have this capability and need the brain to be functioning to send signals to the organs to carry out their functions. A beating heart cadaver requires a ventilator to provide oxygen to its blood, but the heart will continue to beat on its own even in the absence of brain activity. This allows organs to be preserved for a longer period of time in the case of a transplant or donation. A small number of cases in recent years indicate that it can also be implemented for a brain-dead pregnant woman to reach the full term of her pregnancy. There is an advantage to beating heart cadaver organ donation because doctors are able to see the vitals of the organs and tell if they are stable and functioning before transplanting to an ailing patient.
An anatomy murder is a murder committed in order to use all or part of the cadaver for medical research or teaching. It is not a medicine murder because the body parts are not believed to have any medicinal use in themselves. The motive for the murder is created by the demand for cadavers for dissection, and the opportunity to learn anatomy and physiology as a result of the dissection. Rumors concerning the prevalence of anatomy murders are associated with the rise in demand for cadavers in research and teaching produced by the Scientific Revolution. During the 19th century, the sensational serial murders associated with Burke and Hare and the London Burkers led to legislation which provided scientists and medical schools with legal ways of obtaining cadavers. Rumors persist that anatomy murders are carried out wherever there is a high demand for cadavers. These rumors, like those concerning organ theft, are hard to substantiate, and may reflect continued, deep-held fears of the use of cadavers as commodities.
Packing for Mars: The Curious Science of Life in the Void is a nonfiction work by science author Mary Roach.
Grunt: The Curious Science of Humans at War is a nonfiction work by Mary Roach, published in June 2016 by W. W. Norton & Company. It explores the science of protective gear and life-saving technologies used in warfare.
Charles Granville Rob was a British surgeon who pioneered techniques in the repair of damaged blood vessels, particularly the operation to unblock arteries of the neck, known as carotid endarterectomy and of the aorta when treating aortic aneurysms.
