Streptomyces geldanamycininus

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Streptomyces geldanamycininus
Scientific classification
Kingdom: Bacteria
Phylum: Actinobacteria
Class: Actinobacteria
Order: Actinomycetales
Family: Streptomycetaceae
Genus: Streptomyces
Species:S. geldanamycininus
Binomial name
Streptomyces geldanamycininus
Goodfellow et al. 2008 [1]
Type strain
DSM 41894, IFO 14620, NBRC 14620, NRRL 3602, NRRL B-3602, UC 5208 [2]
Synonyms

Streptomyces hygroscopicus var. geldanus, [3]
Streptomyces geldanamycinus, [3]
Streptomyces hygroscopicus subsp. geldanus, [3]

Contents

Streptomyces geldanamycininus is a bacterium species from the genus of Streptomyces . [1] [4] Streptomyces geldanamycininus produces geldanamycin. [4]

<i>Streptomyces</i> genus of Actinobacteria

Streptomyces is the largest genus of Actinobacteria and the type genus of the family Streptomycetaceae. Over 500 species of Streptomyces bacteria have been described. As with the other Actinobacteria, streptomycetes are gram-positive, and have genomes with high GC content. Found predominantly in soil and decaying vegetation, most streptomycetes produce spores, and are noted for their distinct "earthy" odor that results from production of a volatile metabolite, geosmin.

Geldanamycin chemical compound

Geldanamycin is a 1,4-benzoquinone ansamycin antitumor antibiotic that inhibits the function of Hsp90 by binding to the unusual ADP/ATP-binding pocket of the protein. HSP90 client proteins play important roles in the regulation of the cell cycle, cell growth, cell survival, apoptosis, angiogenesis and oncogenesis.

Further reading

International Standard Book Number Unique numeric book identifier

The International Standard Book Number (ISBN) is a numeric commercial book identifier which is intended to be unique. Publishers purchase ISBNs from an affiliate of the International ISBN Agency.

See also

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References

  1. 1 2 LPSN bacterio.net
  2. Straininfo of Streptomyces geldanamycininus
  3. 1 2 3 UniProt
  4. 1 2 Deutsche Sammlung von Mikroorganismen und Zellkulturen