Sweet itch

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Sweet itch sores on a Tunisian pony Dermatitis on pony.jpg
Sweet itch sores on a Tunisian pony

Also known as Queensland itch, seasonal recurrent dermatitis (SSRD), summer itch or more technically, Culicoides hypersensitivity.

Contents

Sweet itch is a medical condition in equines caused by an allergic response to the bites of Culicoides midges. It may be found in horses and ponies, especially in the warmer regions. It may also occur, too, in other equines. [1] It is also found in Canada, Australia, the US and many other parts of the world. [2]

Causes

A hypersensitivity reaction to specific allergens (protein molecules causing an extreme immune response in sensitised individuals) in the saliva of Culicoides midges. There are multiple allergens involved, [3] although some works claim that the larger proteins (of molecular weight 65kDa) are the most important. [4] These allergens appear to be cross-reactive across many species of Culicoides - i.e. many different varieties of midges produce similar allergens, giving the same effects upon horses. [5]

The hypersensitivity response is mediated by IgE, an antibody produced by the horse's immune system which binds the allergens, causing a cascade production of histamine and cytokines which make the horse's skin inflamed and itchy. Of these, histamine appears the most important in the initial phase of reaction. [6]

Symptoms

Treatment and prevention

Few treatments are fully efficacious once lesions have appeared. The only effective form of treatment is preventative - i.e. prevent further insect bites - so these techniques will also be discussed here. Treatments generally fall into one of the following categories:

Overall, the wide variety of treatments proposed leads to the conclusion that no one method is universally effective.

See also

Related Research Articles

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Hypersensitivity Medical condition

Hypersensitivity refers to undesirable reactions produced by the normal immune system, including allergies and autoimmunity. They are usually referred to as an over-reaction of the immune system and these reactions may be damaging and uncomfortable. This is an immunologic term and is not to be confused with the psychiatric term of being hypersensitive which implies to an individual who may be overly sensitive to physical and/or emotional stimuli. Although there is a relation between the two – studies have shown that those individuals that have ADHD are more likely to have hypersensitivity reactions such as allergies, asthma, eczema than those who do not have ADHD.

Type I hypersensitivity Medical condition

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Allergic response

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Cutaneous small-vessel vasculitis Medical condition

Cutaneous small-vessel vasculitis (CSVV), also known as hypersensitivity vasculitis, cutaneous leukocytoclastic vasculitis, hypersensitivity angiitis, cutaneous leukocytoclastic angiitis, cutaneous necrotizing vasculitis and cutaneous necrotizing venulitis, is inflammation of small blood vessels, characterized by palpable purpura. It is the most common vasculitis seen in clinical practice.

Parasitic flies of domestic animals

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Allergies in cats

Cats exposed to allergens may develop allergies or allergic reactions. Allergies tend to become evident and intensify over extended periods of time and can take years to develop. Some allergic diseases and allergies in cats include feline atopic dermatitis, flea allergy dermatitis, feline-mosquito hypersensitivity, and food-induced allergy. In the case of feline atopy, hypersensitivity to allergens is due to genetic predisposition. However, various allergies may arise due to environmental factors. Allergens, ingested, inhaled, or airborne, can be seasonal or non-seasonal, similar to allergies in humans. Suspected seasonal allergens include but are not limited to pollen, fleas, and mosquito bites; suspected non-seasonal allergens include but are not limited to plastic materials, food, dust, trees, and grass. After exposure to suspected allergens, symptoms may be immediate or delayed, arising within a few minutes to two hours. Symptoms can include both dermatological and gastrointestinal signs such as itchy skin, hair loss and excessive scratching. In cases of feline atopic dermatitis or atopy in cats, pruritic skin diseases may result; however, signs can also include miliary dermatitis, symmetrical alopecia, and lesions of the eosinophilic granuloma complex.

Mosquito bite allergy

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Fish allergy Type of food allergy caused by fish

Fish allergy is an immune hypersensitivity to proteins found in fish. Symptoms can be either rapid or gradual in onset. The latter can take hours to days to appear. The former may include anaphylaxis, a potentially life-threatening condition which requires treatment with epinephrine. Other presentations may include atopic dermatitis or inflammation of the esophagus. Fish is one of the eight common food allergens, responsible for 90% of allergic reactions to foods: cow's milk, eggs, wheat, shellfish, peanuts, tree nuts, fish, and soy beans.

References

  1. Queensland Itch by Dr Carl Eden BVM&S MRCVS Retrieved 2011-2-6
  2. GS Anderson, P Belton, & N Kleider (1988) "The Hypersensitivity of Horses to Culicoides Bites in British Columbia", Canadian Veterinary Journal 29(9): 718–723
  3. W. Hellberga, A.D. Wilsonb, P. Mellorc, M.G. Doherra, S. Torsteinsdottird, A. Zurbriggena, T. Jungie and E. Marti (2007) "Equine insect bite hypersensitivity: Immunoblot analysis of IgE and IgG subclass responses to Culicoides nubeculosus salivary gland extract", Veterinary Immunology and Immunopathology Volume 113, Issues 1-2, Pages 99-112
  4. E. Ferroglio, P. Pregel, A. Accossato, I. Taricco, E. Bollo, L. Rossi, A. Trisciuoglio (2006) "Equine Culicoides Hypersensitivity: Evaluation of a Skin Test and of Humoral Response", Journal of Veterinary Medicine, Series A 53 (1), 30–33
  5. Langner, KFA, Darpel, KE, Denison, E, Drolet, BS, Leibold, W, Mellor, PS, Mertens, PPC, Nimtz, M, Greiser-Wilke, I, (2007) "Collection and Analysis of Salivary Proteins from the Biting Midge Culicoides nubeculosus (Diptera: Ceratopogonidae)", Journal of Medical Entomology , Volume 44, Number 2, March 2007, pp. 238-248(11)
  6. A. P. Foster, J. McKelvie, and F. M. Cunningham (1998) "Inhibition of antigen-induced cutaneous responses of ponies with insect hypersensitivity by the histamine-1 receptor antagonist chlorpheniramine", Veterinary Record , Vol 143, Issue 7, 189-193
  7. Animal Health TrustEquine Clinics
  8. PT Colahan, IG Mayhew, AM Merrit & JN Moore, Manual of Equine Medicine and Surgery, Copyright Mosby Inc (1999) (pp. 474-475)
  9. PT Colahan, IG Mayhew, AM Merrit & JN Moore, Manual of Equine Medicine and Surgery, Copyright Mosby Inc (1999) (pp. 474)
  10. J Littlewood (1999) "Control of ectoparasites in horses", In Practice (BVA Publications Ltd) 21: 418-424
  11. PT Colahan, IG Mayhew, AM Merrit & JN Moore, Manual of Equine Medicine and Surgery, Copyright Mosby Inc (1999) (p. 475)
  12. RR Pascoe, DC Knottenbelt, Manual of Equine Dermatology Published 1999, Elsevier Health Sciences (p. 131)
  13. Friberg, Logas (1999) "Treatment of Culicoides hypersensitive horses with high-dose n-3 fatty acids: a double-blinded crossover study" Veterinary Dermatology 10 (2), 117–122
  14. PT Colahan, IG Mayhew, AM Merrit & JN Moore, Manual of Equine Medicine and Surgery, Copyright Mosby Inc (1999) (p. 475)
  15. RJ Rose & DR Hodgson, Manual of Equine Practice, Copyright WB Saunders (2000) (p. 482)
  16. The Holistic Horse