TBRG1

TBRG1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2WZO
Identifiers
Aliases	TBRG1 , NIAM, TB-5, transforming growth factor beta regulator 1
External IDs	OMIM: 610614 MGI: 1100877 HomoloGene: 18102 GeneCards: TBRG1
Gene location (Human)
Chr.	Chromosome 11 (human)
End	124,635,926 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	37,568,608 bp
RNA expression pattern
	Top expressed in
	gastric mucosa; ; rectum; ; monocyte; ; right lung; ; appendix; ; body of pancreas; ; spleen; ; tibia; ; prefrontal cortex; ; upper lobe of left lung;
	Top expressed in
	dermis; ; endocardial cushion; ; seminal vesicula; ; yolk sac; ; molar; ; seminiferous tubule; ; atrium; ; left lung lobe; ; calvaria; ; salivary gland;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding ;
Cellular component	nucleus ;
Biological process	DNA replication ; cell cycle ; protein stabilization ; negative regulation of cell population proliferation ; protein localization to nucleoplasm ;
	Sources:Amigo / QuickGO
Orthologs
	84897
	21376
	ENSG00000154144
	ENSMUSG00000011114
	Q3YBR2
	Q3UB74
	NM_032811
	NM_025289
	NP_116200
	NP_079565
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Transforming growth factor beta regulator 1 is a protein that in humans is encoded by the TBRG1 gene.^[5]^[6]^[7]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000154144 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000011114 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Babalola GO, Schultz RM (Oct 1995). "Modulation of gene expression in the preimplantation mouse embryo by TGF-alpha and TGF-beta". Mol Reprod Dev. 41 (2): 133–9. doi:10.1002/mrd.1080410203. PMID 7654366. S2CID 84997218.
↑ Tompkins VS, Hagen J, Frazier AA, Lushnikova T, Fitzgerald MP, di Tommaso A, Ladeveze V, Domann FE, Eischen CM, Quelle DE (Jan 2007). "A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability". J Biol Chem. 282 (2): 1322–33. doi: 10.1074/jbc.M609612200 . PMID 17110379.
↑ "Entrez Gene: TBRG1 transforming growth factor beta regulator 1".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi: 10.1093/dnares/12.2.117 . PMID 16303743.
Tompkins V, Hagen J, Zediak VP, Quelle DE (2006). "Identification of novel ARF binding proteins by two-hybrid screening". Cell Cycle. 5 (6): 641–6. doi: 10.4161/cc.5.6.2560 . PMID 16582619.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000154144 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000011114 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7654366-5] Babalola GO, Schultz RM (Oct 1995). "Modulation of gene expression in the preimplantation mouse embryo by TGF-alpha and TGF-beta". Mol Reprod Dev. 41 (2): 133–9. doi:10.1002/mrd.1080410203. PMID 7654366. S2CID 84997218.

[pmid17110379-6] Tompkins VS, Hagen J, Frazier AA, Lushnikova T, Fitzgerald MP, di Tommaso A, Ladeveze V, Domann FE, Eischen CM, Quelle DE (Jan 2007). "A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability". J Biol Chem. 282 (2): 1322–33. doi: 10.1074/jbc.M609612200 . PMID 17110379.

[entrez-7] "Entrez Gene: TBRG1 transforming growth factor beta regulator 1".

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TBRG1

Related Research Articles

References

Further reading