TDRKH

TDRKH
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2DIQ, 3FDR, 5J39
Identifiers
Aliases	TDRKH , TDRD2, tudor and KH domain containing
External IDs	OMIM: 609501 MGI: 1919884 HomoloGene: 4999 GeneCards: TDRKH
Gene location (Human)
Chr.	Chromosome 1 (human)
End	151,791,416 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	94,341,975 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; prefrontal cortex; ; ganglionic eminence; ; secondary oocyte; ; islet of Langerhans; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; gastrocnemius muscle; ; right lobe of thyroid gland; ; sural nerve;
	Top expressed in
	mirror; ; secondary oocyte; ; neural tube; ; ganglionic eminence; ; otolith organ; ; utricle; ; medial ganglionic eminence; ; spermatocyte; ; visual cortex; ; seminiferous tubule;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	RNA binding ; nucleic acid binding ;
Cellular component	cytoplasm ; pi-body ; mitochondrion ; piP-body ;
Biological process	male meiotic nuclear division ; fertilization ; cell differentiation ; DNA methylation involved in gamete generation ; spermatogenesis ; gene silencing ; piRNA metabolic process ;
	Sources:Amigo / QuickGO
Orthologs
	11022
	72634
	ENSG00000182134
	ENSMUSG00000041912
	Q9Y2W6
	Q80VL1
	NM_001083963 ; NM_001083964 ; NM_001083965 ; NM_006862
	NM_028307 ; NM_001357711 ; NM_001357712 ; NM_001357713 ; NM_001357714
	NP_001077432 ; NP_001077433 ; NP_001077434 ; NP_006853
	NP_082583 ; NP_001344640 ; NP_001344641 ; NP_001344642 ; NP_001344643
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 12, 2022

Tudor and KH domain-containing protein is a protein that in humans is encoded by the TDRKH gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000182134 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041912 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Lamb FS, Barna TJ, Goud C, Marenholz I, Mischke D, Schutte BC (May 2000). "Complex RNA processing of TDRKH, a novel gene encoding the putative RNA-binding tudor and KH domains". Gene. 246 (1–2): 209–18. doi:10.1016/S0378-1119(00)00087-1. PMID 10767542.
↑ "Entrez Gene: TDRKH tudor and KH domain containing".

Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 . PMID 16344560.
Côté J, Richard S (2005). "Tudor domains bind symmetrical dimethylated arginines". J. Biol. Chem. 280 (31): 28476–83. doi: 10.1074/jbc.M414328200 . PMID 15955813.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000182134 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041912 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10767542-5] Lamb FS, Barna TJ, Goud C, Marenholz I, Mischke D, Schutte BC (May 2000). "Complex RNA processing of TDRKH, a novel gene encoding the putative RNA-binding tudor and KH domains". Gene. 246 (1–2): 209–18. doi:10.1016/S0378-1119(00)00087-1. PMID 10767542.

[entrez-6] "Entrez Gene: TDRKH tudor and KH domain containing".

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TDRKH

Related Research Articles

References

Further reading