THAP2

THAP2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2D8R
Identifiers
Aliases	THAP2 , THAP domain containing 2
External IDs	OMIM: 612531; MGI: 1914066; HomoloGene: 12039; GeneCards: THAP2; OMA:THAP2 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q21.1 Start 71,664,301 bp [1] End 71,680,644 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10|10 D2 Start 115,204,309 bp [2] End 115,220,348 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence ventricular zone left testis right testis testicle monocyte anterior pituitary appendix right uterine tube gallbladder Top expressed in lacrimal gland trigeminal ganglion medial ganglionic eminence tail of embryo genital tubercle ventricular zone transitional epithelium of urinary bladder migratory enteric neural crest cell parotid gland atrioventricular valve More reference expression data BioGPS n/a
Gene ontology Molecular function metal ion binding DNA binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleolus Biological process regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 83591 66816 Ensembl ENSG00000173451 ENSMUSG00000020137 UniProt Q9H0W7 Q9D305 RefSeq (mRNA) NM_031435 NM_025780 RefSeq (protein) NP_113623 NP_080056 Location (UCSC) Chr 12: 71.66 – 71.68 Mb Chr 10: 115.2 – 115.22 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

THAP domain-containing protein 2 is a protein that in humans is encoded by the THAP2 gene. ^{[5] [6]}

References

1. GRCh38: Ensembl release 89: ENSG00000173451 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000020137 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Roussigne M, Kossida S, Lavigne AC, Clouaire T, Ecochard V, Glories A, Amalric F, Girard JP (Feb 2003). "The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase". Trends Biochem Sci. 28 (2): 66–9. doi:10.1016/S0968-0004(02)00013-0. PMID   12575992.
6. "Entrez Gene: THAP2 THAP domain containing, apoptosis associated protein 2".

Further reading

• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.