THAP4

THAP4
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3IA8
Identifiers
Aliases	THAP4 , PP238, CGI-36, THAP domain containing 4, Nb(III)
External IDs	OMIM: 612533; MGI: 1914276; HomoloGene: 12075; GeneCards: THAP4; OMA:THAP4 - orthologs
Gene location (Human) Chr. Chromosome 2 (human) [1] Band 2q37.3 Start 241,584,405 bp [1] End 241,637,158 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 D Start 93,629,657 bp [2] End 93,682,586 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in apex of heart mucosa of transverse colon right auricle of heart muscle of thigh left ventricle gastrocnemius muscle human kidney renal medulla putamen caudate nucleus Top expressed in seminiferous tubule spermatocyte choroid plexus of fourth ventricle epithelium of stomach spermatid right kidney tail of embryo human kidney large intestine left colon More reference expression data BioGPS n/a
Gene ontology Molecular function metal ion binding DNA binding nucleic acid binding heme binding protein homodimerization activity DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component cellular component Biological process biological process regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51078 67026 Ensembl ENSG00000176946 ENSMUSG00000026279 UniProt Q8WY91 Q6P3Z3 RefSeq (mRNA) NM_001164356 NM_015963 NM_025920 NM_001310761 RefSeq (protein) NP_001157828 NP_057047 NP_001297690 NP_080196 Location (UCSC) Chr 2: 241.58 – 241.64 Mb Chr 1: 93.63 – 93.68 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

THAP domain-containing protein 4 is a protein that in humans is encoded by the THAP4 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000176946 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000026279 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Roussigne M, Kossida S, Lavigne AC, Clouaire T, Ecochard V, Glories A, Amalric F, Girard JP (Feb 2003). "The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase". Trends Biochem Sci. 28 (2): 66–9. doi:10.1016/S0968-0004(02)00013-0. PMID   12575992.
6. Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC   310876 . PMID   10810093.
7. "Entrez Gene: THAP4 THAP domain containing 4".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. Bibcode:2004PNAS..10115724W. doi: 10.1073/pnas.0404089101 . PMC   524842 . PMID   15498874.
• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi: 10.1038/nature03466 . PMID   15815621.