THAP4

THAP4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3IA8
Identifiers
Aliases	THAP4 , PP238, CGI-36, THAP domain containing 4, Nb(III)
External IDs	OMIM: 612533 MGI: 1914276 HomoloGene: 12075 GeneCards: THAP4
Gene location (Human)
Chr.	Chromosome 2 (human)
End	241,637,158 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	93,682,586 bp
RNA expression pattern
	Top expressed in
	left ventricle; ; gastrocnemius muscle; ; kidney; ; renal medulla; ; putamen; ; caudate nucleus; ; body of stomach; ; nucleus accumbens; ; triceps brachii muscle; ; prefrontal cortex;
	Top expressed in
	seminiferous tubule; ; spermatocyte; ; Epithelium of stomach; ; spermatid; ; kidney; ; large intestine; ; left colon; ; duodenum; ; right ventricle; ; mucous cell of stomach;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding ; DNA binding ; nucleic acid binding ; heme binding ; protein homodimerization activity ; DNA-binding transcription factor activity, RNA polymerase II-specific ;
Cellular component	cellular component ;
Biological process	biological process ; regulation of transcription by RNA polymerase II ;
	Sources:Amigo / QuickGO
Orthologs
	51078
	67026
	ENSG00000176946
	ENSMUSG00000026279
	Q8WY91
	Q6P3Z3
	NM_001164356 ; NM_015963
	NM_025920 ; NM_001310761
	NP_001157828 ; NP_057047
	NP_001297690 ; NP_080196
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

THAP domain-containing protein 4 is a protein that in humans is encoded by the THAP4 gene.^[5]^[6]^[7]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000176946 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000026279 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Roussigne M, Kossida S, Lavigne AC, Clouaire T, Ecochard V, Glories A, Amalric F, Girard JP (Feb 2003). "The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase". Trends Biochem Sci. 28 (2): 66–9. doi:10.1016/S0968-0004(02)00013-0. PMID 12575992.
↑ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876 . PMID 10810093.
↑ "Entrez Gene: THAP4 THAP domain containing 4".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. Bibcode:2004PNAS..10115724W. doi: 10.1073/pnas.0404089101 . PMC 524842 . PMID 15498874.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi: 10.1038/nature03466 . PMID 15815621.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000176946 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000026279 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12575992-5] Roussigne M, Kossida S, Lavigne AC, Clouaire T, Ecochard V, Glories A, Amalric F, Girard JP (Feb 2003). "The THAP domain: a novel protein motif with similarity to the DNA-binding domain of P element transposase". Trends Biochem Sci. 28 (2): 66–9. doi:10.1016/S0968-0004(02)00013-0. PMID 12575992.

[pmid10810093-6] Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876 . PMID 10810093.

[entrez-7] "Entrez Gene: THAP4 THAP domain containing 4".

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[5]

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[7]

THAP4

Related Research Articles

References

Further reading