TIPARP

TIPARP
Identifiers
Aliases	TIPARP , ARTD14, PARP7, pART14, TCDD inducible poly(ADP-ribose) polymerase
External IDs	OMIM: 612480 MGI: 2159210 HomoloGene: 9167 GeneCards: TIPARP
Gene location (Human)
Chr.	Chromosome 3 (human)
End	156,706,770 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	65,462,939 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; vena cava; ; caput epididymis; ; Achilles tendon; ; mucosa of urinary bladder; ; urethra; ; palpebral conjunctiva; ; stromal cell of endometrium; ; left uterine tube; ; bronchial epithelial cell;
	Top expressed in
	secondary oocyte; ; sciatic nerve; ; medial ganglionic eminence; ; spermatocyte; ; utricle; ; brown adipose tissue; ; ovary; ; renal corpuscle; ; cumulus cell; ; calvaria;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity ; glycosyltransferase activity ; metal ion binding ; NAD+ ADP-ribosyltransferase activity ; protein ADP-ribosylase activity ;
Cellular component	nucleus ;
Biological process	roof of mouth development ; protein ADP-ribosylation ; positive regulation of protein catabolic process ; estrogen metabolic process ; androgen metabolic process ; kidney development ; skeletal system morphogenesis ; cellular response to organic cyclic compound ; post-embryonic development ; negative regulation of gene expression ; female gonad development ; vasculogenesis ; nitrogen compound metabolic process ; smooth muscle tissue development ; platelet-derived growth factor receptor signaling pathway ; face morphogenesis ; hemopoiesis ; response to 2,3,7,8-tetrachlorodibenzodioxine ; protein auto-ADP-ribosylation ; protein mono-ADP-ribosylation ;
	Sources:Amigo / QuickGO
Orthologs
	25976
	99929
	ENSG00000163659
	ENSMUSG00000034640
	Q7Z3E1
	Q8C1B2
	NM_001184717 ; NM_001184718 ; NM_015508
	NM_178892
	NP_001171646 ; NP_001171647 ; NP_056323
	NP_849223
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 18, 2022

TCDD-inducible poly [ADP-ribose] polymerase is an enzyme that in humans is encoded by the TIPARP gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000163659 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034640 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Katoh M, Katoh M (Jul 2003). "Identification and characterization of human TIPARP gene within the CCNL amplicon at human chromosome 3q25.31". Int J Oncol. 23 (2): 541–7. doi:10.3892/ijo.23.2.541. PMID 12851707.
↑ "Entrez Gene: TIPARP TCDD-inducible poly(ADP-ribose) polymerase".

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Ménisser-de Murcia J, Mark M, Wendling O, et al. (2001). "Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during development". Mol. Cell. Biol. 21 (5): 1828–32. doi:10.1128/MCB.21.5.1828-1832.2001. PMC 86747 . PMID 11238919.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147 . PMID 15231747.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000163659 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000034640 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12851707-5] Katoh M, Katoh M (Jul 2003). "Identification and characterization of human TIPARP gene within the CCNL amplicon at human chromosome 3q25.31". Int J Oncol. 23 (2): 541–7. doi:10.3892/ijo.23.2.541. PMID 12851707.

[entrez-6] "Entrez Gene: TIPARP TCDD-inducible poly(ADP-ribose) polymerase".

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TIPARP

Contents

See also

Related Research Articles

References

Further reading