TIPARP

TIPARP
Identifiers
Aliases	TIPARP , ARTD14, PARP7, pART14, TCDD inducible poly(ADP-ribose) polymerase
External IDs	OMIM: 612480; MGI: 2159210; HomoloGene: 9167; GeneCards: TIPARP; OMA:TIPARP - orthologs
Gene location (Human) Chr. Chromosome 3 (human) [1] Band 3q25.31 Start 156,673,235 bp [1] End 156,706,770 bp [1]
Gene location (Mouse) Chr. Chromosome 3 (mouse) [2] Band 3|3 E1 Start 65,435,831 bp [2] End 65,462,939 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte skin of thigh vena cava tail of epididymis caput epididymis Achilles tendon mucosa of urinary bladder mucosa of pharynx urethra palpebral conjunctiva Top expressed in zygote secondary oocyte primary oocyte epithelium of lens sciatic nerve medial ganglionic eminence spermatocyte tail of embryo transitional epithelium of urinary bladder decidua More reference expression data BioGPS More reference expression data
Gene ontology Molecular function transferase activity glycosyltransferase activity metal ion binding NAD+ ADP-ribosyltransferase activity protein ADP-ribosylase activity Cellular component nucleus Biological process roof of mouth development protein ADP-ribosylation positive regulation of protein catabolic process estrogen metabolic process androgen metabolic process kidney development skeletal system morphogenesis cellular response to organic cyclic compound post-embryonic development negative regulation of gene expression female gonad development vasculogenesis nitrogen compound metabolic process smooth muscle tissue development platelet-derived growth factor receptor signaling pathway face morphogenesis hemopoiesis response to 2,3,7,8-tetrachlorodibenzodioxine protein auto-ADP-ribosylation protein mono-ADP-ribosylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 25976 99929 Ensembl ENSG00000163659 ENSMUSG00000034640 UniProt Q7Z3E1 Q8C1B2 RefSeq (mRNA) NM_001184717 NM_001184718 NM_015508 NM_178892 RefSeq (protein) NP_001171646 NP_001171647 NP_056323 NP_849223 Location (UCSC) Chr 3: 156.67 – 156.71 Mb Chr 3: 65.44 – 65.46 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

TCDD-inducible poly [ADP-ribose] polymerase is an enzyme that in humans is encoded by the TIPARP gene. ^{[5] [6]}

See also

• TCDD, or 2,3,7,8-Tetrachlorodibenzodioxin

References

1. GRCh38: Ensembl release 89: ENSG00000163659 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000034640 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Katoh M, Katoh M (Jul 2003). "Identification and characterization of human TIPARP gene within the CCNL amplicon at human chromosome 3q25.31". Int J Oncol. 23 (2): 541–7. doi:10.3892/ijo.23.2.541. PMID   12851707.
6. "Entrez Gene: TIPARP TCDD-inducible poly(ADP-ribose) polymerase".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Ménisser-de Murcia J, Mark M, Wendling O, et al. (2001). "Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during development". Mol. Cell. Biol. 21 (5): 1828–32. doi:10.1128/MCB.21.5.1828-1832.2001. PMC   86747 . PMID   11238919.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC   442147 . PMID   15231747.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.