TLL2

Last updated
TLL2
Identifiers
Aliases TLL2 , tolloid like 2
External IDs OMIM: 606743 MGI: 1346044 HomoloGene: 56545 GeneCards: TLL2
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012465

NM_011904

RefSeq (protein)

NP_036597

NP_036034

Location (UCSC) Chr 10: 96.36 – 96.51 Mb Chr 19: 41.07 – 41.2 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Tolloid-like protein 2 is a protein that in humans is encoded by the TLL2 gene. [5] [6]

This gene encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. Unlike other family members, a similar protein in mice does not cleave procollagen C-propeptides or chordin. [6]

Related Research Articles

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<span class="mw-page-title-main">TLL1</span>

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<span class="mw-page-title-main">Mitochondrial ribosomal protein L37</span> Protein-coding gene in the species Homo sapiens

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000095587 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025013 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Scott IC, Clark TG, Takahara K, Hoffman GG, Eddy RL, Haley LL, Shows TB, Greenspan DS (Oct 1999). "Assignment of TLL1 and TLL2, which encode human BMP-1/Tolloid-related metalloproteases, to chromosomes 4q32→q33 and 10q23→q24 and assignment of murine Tll2 to chromosome 19". Cytogenet Cell Genet. 86 (1): 64–5. doi:10.1159/000015412. PMID   10516436. S2CID   42081614.
  6. 1 2 "Entrez Gene: TLL2 tolloid-like 2".

Further reading