TMCO1

TMCO1
Identifiers
Aliases	TMCO1 , HP10122, PCIA3, PNAS-136, TMCC4, transmembrane and coiled-coil domains 1
External IDs	OMIM: 614123; MGI: 1921173; HomoloGene: 10384; GeneCards: TMCO1; OMA:TMCO1 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q24.1 Start 165,724,293 bp [1] End 165,827,755 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 H2.3 Start 167,135,947 bp [2] End 167,161,547 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon Epithelium of choroid plexus rectum islet of Langerhans jejunal mucosa gallbladder mucosa of colon mucosa of transverse colon bronchial epithelial cell mucosa of sigmoid colon Top expressed in right kidney seminal vesicula molar parotid gland left lung lobe spermatocyte decidua submandibular gland atrioventricular valve human kidney More reference expression data BioGPS More reference expression data
Gene ontology Molecular function calcium channel activity Cellular component membrane endoplasmic reticulum membrane Golgi membrane Golgi apparatus integral component of membrane endoplasmic reticulum integral component of endoplasmic reticulum membrane Biological process calcium ion transport ER overload response ion transport calcium ion transmembrane transport endoplasmic reticulum calcium ion homeostasis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 54499 68944 Ensembl ENSG00000143183 ENSMUSG00000052428 UniProt Q9UM00 Q921L3 RefSeq (mRNA) NM_001256164 NM_001256165 NM_019026 NM_001366129 NM_001039483 NM_026881 RefSeq (protein) NP_001243093 NP_001243094 NP_061899 NP_001034572 Location (UCSC) Chr 1: 165.72 – 165.83 Mb Chr 1: 167.14 – 167.16 Mb PubMed search [3] [4]
Wikidata
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Transmembrane and coiled-coil domain-containing protein 1 is a protein that in humans is encoded by the TMCO1 gene. ^{[5] [6] [7]}

References

1. GRCh38: Ensembl release 89: ENSG00000143183 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000052428 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (Jun 1996). "A "double adaptor" method for improved shotgun library construction". Anal Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID   8619474.
6. Yu W, Andersson B, Worley KC, Muzny DM, Ding Y, Liu W, Ricafrente JY, Wentland MA, Lennon G, Gibbs RA (Jun 1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC   139146 . PMID   9110174.
7. "Entrez Gene: TMCO1 transmembrane and coiled-coil domains 1".

Further reading

• Iwamuro S, Saeki M, Kato S (1999). "Multi-ubiquitination of a nascent membrane protein produced in a rabbit reticulocyte lysate". J. Biochem. 126 (1): 48–53. doi:10.1093/oxfordjournals.jbchem.a022435. PMID   10393320.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi: 10.1073/pnas.0507066103 . PMC   1459365 . PMID   16565220.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi: 10.1016/j.cell.2006.09.026 . PMID   17081983. S2CID   7827573.