TMEM109

TMEM109
Identifiers
Aliases	TMEM109 , transmembrane protein 109
External IDs	MGI: 1915789 HomoloGene: 11458 GeneCards: TMEM109
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.2 Start 60,914,158 bp [1] End 60,923,443 bp [1]
Gene location (Mouse) Chr. Chromosome 19 (mouse) [2] Band 19|19 A Start 10,848,024 bp [2] End 10,859,365 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in thoracic aorta ascending aorta right coronary artery left coronary artery tibial nerve popliteal artery right lung canal of the cervix left uterine tube upper lobe of left lung Top expressed in ascending aorta aortic valve conjunctival fornix vastus lateralis muscle internal carotid artery masseter muscle intercostal muscle Paneth cell external carotid artery triceps brachii muscle More reference expression data BioGPS n/a
Gene ontology Molecular function voltage-gated ion channel activity molecular function protein binding Cellular component sarcoplasmic reticulum membrane extracellular exosome endoplasmic reticulum membrane nucleus membrane sarcoplasmic reticulum nuclear outer membrane integral component of membrane endoplasmic reticulum Biological process ion transport negative regulation of cell death cellular response to gamma radiation intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator regulation of ion transmembrane transport transport ion transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79073 68539 Ensembl ENSG00000110108 ENSMUSG00000034659 UniProt Q9BVC6 Q3UBX0 RefSeq (mRNA) NM_024092 NM_134142 RefSeq (protein) NP_076997 NP_598903 Location (UCSC) Chr 11: 60.91 – 60.92 Mb Chr 19: 10.85 – 10.86 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Transmembrane protein 109 is a protein that in humans is encoded by the TMEM109 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000110108 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000034659 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Transmembrane protein 109" . Retrieved 2016-07-02.

Further reading

• Yamazaki T, Sasaki N, Nishi M, Takeshima H (2010). "Facilitation of DNA damage-induced apoptosis by endoplasmic reticulum protein mitsugumin23". Biochem. Biophys. Res. Commun. 392 (2): 196–200. doi:10.1016/j.bbrc.2010.01.013. PMID   20060811.