TMTC2

TMTC2
Identifiers
Aliases	TMTC2 , IBDBP1, transmembrane and tetratricopeptide repeat containing 2, transmembrane O-mannosyltransferase targeting cadherins 2
External IDs	OMIM: 615856; MGI: 1914057; HomoloGene: 25521; GeneCards: TMTC2; OMA:TMTC2 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q21.31 Start 82,686,880 bp [1] End 83,134,870 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10|10 D1 Start 105,023,524 bp [2] End 105,410,312 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ventricular zone corpus callosum mucosa of paranasal sinus ganglionic eminence caput epididymis C1 segment corpus epididymis right uterine tube inferior ganglion of vagus nerve tail of epididymis Top expressed in hand cumulus cell renal capsule body of femur clavicle vas deferens molar left lung lobe olfactory epithelium membranous bone More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding mannosyltransferase activity dolichyl-phosphate-mannose-protein mannosyltransferase activity transferase activity Cellular component integral component of membrane endoplasmic reticulum membrane endoplasmic reticulum membrane Biological process calcium ion homeostasis protein O-linked mannosylation protein glycosylation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 160335 278279 Ensembl ENSG00000179104 ENSMUSG00000036019 UniProt Q8N394 Q56A06 RefSeq (mRNA) NM_152588 NM_001320321 NM_001320322 NM_177368 RefSeq (protein) NP_001307250 NP_001307251 NP_689801 NP_796342 Location (UCSC) Chr 12: 82.69 – 83.13 Mb Chr 10: 105.02 – 105.41 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Transmembrane and TPR repeat-containing protein 2 is a protein that in humans is encoded by the TMTC2 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000179104 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000036019 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: TMTC2 transmembrane and tetratricopeptide repeat containing 2".

Further reading

• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.