TMTC2

TMTC2
Identifiers
Aliases	TMTC2 , IBDBP1, transmembrane and tetratricopeptide repeat containing 2, transmembrane O-mannosyltransferase targeting cadherins 2
External IDs	OMIM: 615856 MGI: 1914057 HomoloGene: 25521 GeneCards: TMTC2
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q21.31 Start 82,686,880 bp [1] End 83,134,870 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10|10 D1 Start 105,187,663 bp [2] End 105,574,451 bp [2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • mannosyltransferase activity • dolichyl-phosphate-mannose-protein mannosyltransferase activity • transferase activity Cellular component • integral component of membrane • endoplasmic reticulum membrane • endoplasmic reticulum • membrane Biological process • calcium ion homeostasis • protein O-linked mannosylation • protein glycosylation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	160335	278279
Ensembl	ENSG00000179104	ENSMUSG00000036019
UniProt	Q8N394	Q56A06
RefSeq (mRNA)	NM_152588 NM_001320321 NM_001320322	NM_177368
RefSeq (protein)	NP_001307250 NP_001307251 NP_689801	NP_796342
Location (UCSC)	Chr 12: 82.69 – 83.13 Mb	Chr 10: 105.19 – 105.57 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Transmembrane and TPR repeat-containing protein 2 is a protein that in humans is encoded by the TMTC2 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000179104 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000036019 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: TMTC2 transmembrane and tetratricopeptide repeat containing 2".

Further reading

• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.