TNFAIP8

Last updated
TNFAIP8
Identifiers
Aliases TNFAIP8 , GG2-1, MDC-3.13, NDED, SCC-S2, SCCS2, TNF alpha induced protein 8
External IDs OMIM: 612111 MGI: 2147191 HomoloGene: 8649 GeneCards: TNFAIP8
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001177759
NM_001177760
NM_134131
NM_001360935

RefSeq (protein)

NP_001171230
NP_001171231
NP_598892
NP_001347864

Location (UCSC) Chr 5: 119.27 – 119.4 Mb Chr 18: 49.98 – 50.11 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Tumor necrosis factor, alpha-induced protein 8 is a protein that in humans is encoded by the TNFAIP8 gene. [5] [6] [7] It is preferentially expressed in human immune cell types. [8]


Related Research Articles

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TNFSF18

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TNFAIP8L2

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References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000145779 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000062210 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Horrevoets AJ, Fontijn RD, van Zonneveld AJ, de Vries CJ, ten Cate JW, Pannekoek H (Jun 1999). "Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes". Blood. 93 (10): 3418–31. doi:10.1182/blood.V93.10.3418.410k23_3418_3431. PMID   10233894.
  6. Kumar D, Whiteside TL, Kasid U (Feb 2000). "Identification of a novel tumor necrosis factor-alpha-inducible gene, SCC-S2, containing the consensus sequence of a death effector domain of fas-associated death domain-like interleukin- 1beta-converting enzyme-inhibitory protein". J Biol Chem. 275 (4): 2973–8. doi: 10.1074/jbc.275.4.2973 . PMID   10644768.
  7. "Entrez Gene: TNFAIP8 tumor necrosis factor, alpha-induced protein 8".
  8. Li T, Wang W, et al. (May 2018). "Genome-wide analysis reveals TNFAIP8L2 as an immune checkpoint regulator of inflammation and metabolism". Molecular Immunology. 99: 154–162. doi:10.1016/j.molimm.2018.05.007. PMC   5995464 . PMID   29787979.

Further reading