TOM1L2

TOM1L2
Identifiers
Aliases	TOM1L2 , target of myb1 like 2 membrane trafficking protein
External IDs	OMIM: 615519 MGI: 2443306 HomoloGene: 44901 GeneCards: TOM1L2
Gene location (Human)
Chr.	Chromosome 17 (human)
End	17,972,422 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	60,243,731 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; left ventricle; ; right lobe of thyroid gland; ; amygdala; ; left lobe of thyroid gland; ; nucleus accumbens; ; skin of abdomen; ; cingulate gyrus; ; right coronary artery; ; ventral tegmental area;
	Top expressed in
	habenula; ; pontine nuclei; ; superior colliculus; ; dorsal tegmental nucleus; ; subiculum; ; ventral tegmental area; ; superior frontal gyrus; ; medial vestibular nucleus; ; primary motor cortex; ; dorsomedial hypothalamic nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	clathrin binding ; protein binding ; protein kinase binding ;
Cellular component	extracellular exosome ; intracellular anatomical structure ;
Biological process	protein transport ; intracellular protein transport ; negative regulation of mitotic nuclear division ; signal transduction ; transport ;
	Sources:Amigo / QuickGO
Orthologs
	146691
	216810
	ENSG00000175662
	ENSMUSG00000000538
	Q6ZVM7
	Q5SRX1
NM_001033551 ; NM_001082968 ; NM_001288786 ; NM_001288787 ; NM_001288788 ;
	NM_001288789 ; NM_144678 ; NM_001350331 ; NM_001350332 ; NM_001350333
	NM_001039092 ; NM_001039093 ; NM_153080 ; NM_001359810
NP_001028723 ; NP_001076437 ; NP_001275715 ; NP_001275716 ; NP_001275717 ;
	NP_001275718 ; NP_001337260 ; NP_001337261 ; NP_001337262
NP_001034181 ; NP_001034182 ; NP_694720 ; NP_001346739 ; NP_001390817 ;
	NP_001390820 ; NP_001390822 ; NP_001390824 ; NP_001390825
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 05, 2023

TOM1-like protein 2 is a protein that in humans is encoded by the TOM1L2 gene.^[5]^[6]

Related Research Articles

DNA methyltransferase 1-associated protein 1 is an enzyme that in humans is encoded by the DMAP1 gene.

Protein unc-84 homolog B is a protein that in humans is encoded by the UNC84B gene.

Zinc finger protein 593 is a protein that in humans is encoded by the ZNF593 gene.

Nuclear receptor-binding protein is a protein that in humans is encoded by the NRBP1 gene.

40S ribosomal protein S17 is a protein that in humans is encoded by the RPS17 gene.

40S ribosomal protein S20 is a protein that in humans is encoded by the RPS20 gene.

Epsin-2 is a protein that in humans is encoded by the EPN2 gene.

Serine/threonine-protein kinase PCTAIRE-3 is an enzyme that in humans is encoded by the PCTK3 gene.

40S ribosomal protein S8 is a protein that in humans is encoded by the RPS8 gene.

BTB/POZ domain-containing protein KCTD12 is a protein that in humans is encoded by the KCTD12 gene.

Mitochondrial dynamic protein MID51 (MID51) also known as mitochondrial elongation factor 1 (MIEF1) or Smith-Magenis syndrome chromosome region candidate gene 7 protein-like (SMCR7L) is a protein that in humans is encoded by the SMCR7L gene.

Transmembrane and ubiquitin-like domain-containing protein 2 is a protein that in humans is encoded by the TMUB2 gene.

Nucleoporin 155 (Nup155) is a protein that in humans is encoded by the NUP155 gene.

Leucine-rich repeat-containing protein 48 is a protein that in humans is encoded by the LRRC48 gene.

Protein TRS85 homolog is a protein that in humans is encoded by the KIAA1012 gene.

CDK12 cyclin-dependent kinase 12 is a protein kinase that in humans is encoded by the CDK12 gene. This enzyme is a member of cyclin-dependent kinase protein family.

Prostate tumor overexpressed gene 1 protein is a protein that in humans is encoded by the PTOV1 gene.

TOX4 also known as KIAA0737, is a human gene.

Dehydrogenase/reductase X-linked also known as DHRSX is an enzyme which in humans is encoded by the pseudoautosomal DHRSX gene. DHRSX is a member of the short-chain dehydrogenase family of oxidoreductase enzymes.

The Coiled-Coil Domain Containing Protein – 25 (CCDC25) is a human protein whose function is not presently understood.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000175662 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000000538 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Seranski P, Heiss NS, Dhorne-Pollet S, Radelof U, Korn B, Hennig S, Backes E, Schmidt S, Wiemann S, Schwarz CE, Lehrach H, Poustka A (May 1999). "Transcription mapping in a medulloblastoma breakpoint interval and Smith-Magenis syndrome candidate region: identification of 53 transcriptional units and new candidate genes". Genomics. 56 (1): 1–11. doi:10.1006/geno.1998.5647. PMID 10036180.
↑ "Entrez Gene: TOM1L2 target of myb1-like 2 (chicken)".

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi: 10.1101/gr.6.9.791 . PMID 8889548.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-Scale Concatenation cDNA Sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146 . PMID 9110174.
Bi W, Yan J, Stankiewicz P, et al. (2002). "Genes in a Refined Smith-Magenis Syndrome Critical Deletion Interval on Chromosome 17p11.2 and the Syntenic Region of the Mouse". Genome Res. 12 (5): 713–28. doi:10.1101/gr.73702. PMC 186594 . PMID 11997338.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697 . PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148 . PMID 15231748.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Zhang Y, Wolf-Yadlin A, Ross PL, et al. (2005). "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules". Mol. Cell. Proteomics. 4 (9): 1240–50. doi: 10.1074/mcp.M500089-MCP200 . PMID 15951569.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 . PMID 16344560.
Katoh Y, Imakagura H, Futatsumori M, Nakayama K (2006). "Recruitment of clathrin onto endosomes by the Tom1-Tollip complex". Biochem. Biophys. Res. Commun. 341 (1): 143–9. doi:10.1016/j.bbrc.2005.12.156. PMID 16412388.
Franco M, Furstoss O, Simon V, et al. (2006). "The Adaptor Protein Tom1L1 Is a Negative Regulator of Src Mitogenic Signaling Induced by Growth Factors". Mol. Cell. Biol. 26 (5): 1932–47. doi:10.1128/MCB.26.5.1932-1947.2006. PMC 1430241 . PMID 16479011.

This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000175662 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000000538 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10036180-5] Seranski P, Heiss NS, Dhorne-Pollet S, Radelof U, Korn B, Hennig S, Backes E, Schmidt S, Wiemann S, Schwarz CE, Lehrach H, Poustka A (May 1999). "Transcription mapping in a medulloblastoma breakpoint interval and Smith-Magenis syndrome candidate region: identification of 53 transcriptional units and new candidate genes". Genomics. 56 (1): 1–11. doi:10.1006/geno.1998.5647. PMID 10036180.

[entrez-6] "Entrez Gene: TOM1L2 target of myb1-like 2 (chicken)".

[1]

[2]

[3]

[4]

[5]

[6]

TOM1L2

Related Research Articles

References

Further reading