TOMM40L

TOMM40L
Identifiers
Aliases	TOMM40L , TOMM40B, translocase of outer mitochondrial membrane 40 like
External IDs	MGI: 3589112; HomoloGene: 134180; GeneCards: TOMM40L; OMA:TOMM40L - orthologs
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q23.3 Start 161,225,939 bp [1] End 161,230,746 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 H3 Start 171,043,580 bp [2] End 171,050,083 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in myocardium of left ventricle apex of heart right lobe of liver prefrontal cortex right auricle of heart right frontal lobe dorsolateral prefrontal cortex anterior cingulate cortex mucosa of transverse colon Brodmann area 9 Top expressed in interventricular septum otic vesicle dentate gyrus of hippocampal formation granule cell saccule superior frontal gyrus muscle of thigh visual cortex motor neuron otic placode extraocular muscle More reference expression data BioGPS n/a
Gene ontology Molecular function porin activity molecular function protein transmembrane transporter activity mitochondrion targeting sequence binding preprotein binding Cellular component integral component of membrane mitochondrial outer membrane pore complex mitochondrion membrane mitochondrial outer membrane translocase complex protein-containing complex Biological process protein transport ion transport transmembrane transport biological process protein import into mitochondrial matrix Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84134 641376 Ensembl ENSG00000158882 ENSMUSG00000005674 UniProt Q969M1 Q9CZR3 RefSeq (mRNA) NM_001286373 NM_001286374 NM_032174 NM_001037170 RefSeq (protein) NP_001273302 NP_001273303 NP_115550 NP_001032247 Location (UCSC) Chr 1: 161.23 – 161.23 Mb Chr 1: 171.04 – 171.05 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Mitochondrial import receptor subunit TOM40B is a protein that in humans is encoded by the TOMM40L gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000158882 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000005674 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like".

Further reading

• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC   310948 . PMID   11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC   311072 . PMID   11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC   1083732 . PMID   11256614.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID   14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC   528930 . PMID   15489336.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC   1356129 . PMID   16344560.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC   1347501 . PMID   16381901.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.