TOMM40L

TOMM40L
Identifiers
Aliases	TOMM40L , TOMM40B, translocase of outer mitochondrial membrane 40 like
External IDs	MGI: 3589112 HomoloGene: 134180 GeneCards: TOMM40L
Gene location (Human)
Chr.	Chromosome 1 (human)
End	161,230,746 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	171,050,083 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; prefrontal cortex; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; muscle of leg; ; gastrocnemius muscle; ; vastus lateralis muscle; ; middle temporal gyrus; ; right ventricle; ; bone marrow cells;
	Top expressed in
	interventricular septum; ; saccule; ; superior frontal gyrus; ; visual cortex; ; motor neuron; ; otic placode; ; extraocular muscle; ; substantia nigra; ; left ventricle; ; yolk sac;
	More reference expression data
	n/a
Gene ontology
Molecular function	porin activity ; molecular function ; protein transmembrane transporter activity ; mitochondrion targeting sequence binding ; preprotein binding ;
Cellular component	integral component of membrane ; mitochondrial outer membrane ; pore complex ; mitochondrion ; membrane ; mitochondrial outer membrane translocase complex ; protein-containing complex ;
Biological process	protein transport ; ion transport ; transmembrane transport ; biological process ; protein import into mitochondrial matrix ;
	Sources:Amigo / QuickGO
Orthologs
	84134
	641376
	ENSG00000158882
	ENSMUSG00000005674
	Q969M1
	Q9CZR3
	NM_001286373 ; NM_001286374 ; NM_032174
	NM_001037170
	NP_001273302 ; NP_001273303 ; NP_115550
	NP_001032247
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated October 12, 2022

Mitochondrial import receptor subunit TOM40B is a protein that in humans is encoded by the TOMM40L gene.^[5]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000158882 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000005674 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like".

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732 . PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129 . PMID 16344560.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID 16710414.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000158882 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000005674 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: TOMM40L translocase of outer mitochondrial membrane 40 homolog (yeast)-like".

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TOMM40L

Related Research Articles

References

Further reading