T-cell receptor-associated transmembrane adapter 1 is a protein that in humans is encoded by the TRAT1 gene. [5] [6] [7]
T-cell receptor-associated transmembrane adapter 1 is a protein that in humans is encoded by the TRAT1 gene. [5] [6] [7]
CD5 is a cluster of differentiation expressed on the surface of T cells and in a subset of murine B cells known as B-1a. The expression of this receptor in human B cells has been a controversial topic and to date there is no consensus regarding the role of this receptor as a marker of human B cells. B-1 cells have limited diversity of their B-cell receptor due to their lack of the enzyme terminal deoxynucleotidyl transferase (TdT) and are potentially self-reactive. CD5 serves to mitigate activating signals from the BCR so that the B-1 cells can only be activated by very strong stimuli and not by normal tissue proteins. CD5 was used as a T-cell marker until monoclonal antibodies against CD3 were developed.
The Linker for activation of T cells, also known as linker of activated T cells or LAT, is a protein involved in the T-cell antigen receptor signal transduction pathway which in humans is encoded by the LAT gene. Alternative splicing results in multiple transcript variants encoding different isoforms.
CD244 also known as 2B4 or SLAMF4 is a protein that in humans is encoded by the CD244 gene.
Linker for activation of T-cells family member 2 is a protein that in humans is encoded by the LAT2 gene.
Killer cell immunoglobulin-like receptor 3DL2 is a protein that in humans is encoded by the KIR3DL2 gene.
Src kinase-associated phosphoprotein 2 is an enzyme that in humans is encoded by the SKAP2 gene.
SLAM family member 6 is a protein that in humans is encoded by the SLAMF6 gene.
Src kinase-associated phosphoprotein 1 is an adapter protein that in humans is encoded by the SKAP1 gene.
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide is a protein that in humans is encoded by the DAPP1 gene.
Porimin is a protein that in humans is encoded by the TMEM123 gene.
Leukocyte immunoglobulin-like receptor subfamily B member 3 is a protein that in humans is encoded by the LILRB3 gene.
Signaling threshold-regulating transmembrane adapter 1 is a protein that in humans is encoded by the SIT1 gene.
PML-RARA-regulated adapter molecule 1 is a protein that in humans is encoded by the PRAM1 gene.
CD320 is a human gene.
Lck-interacting transmembrane adapter 1 is a protein that in humans is encoded by the LIME1 gene.
Protein tyrosine phosphatase receptor type C-associated protein is an enzyme that in humans is encoded by the PTPRCAP gene.
T-cell surface glycoprotein CD3 delta chain is a protein that in humans is encoded by the CD3D gene.
T-cell receptor alpha locus is a protein that in humans is encoded by the TRA gene, also known as TCRA or TRA@. It contributes the alpha chain to the larger TCR protein.
TIR domain-containing adapter molecule 2 is a protein that in humans is encoded by the TICAM2 gene.
SLP65/SLP76, Csk-interacting membrane protein, termed SCIMP, belongs to family of transmembrane adaptor proteins (TRAP) which do not directly associate with a receptor, such as LAT, NTAL, LIME or LAX. SCIMP is expressed in antigen-presenting cells (APC), namely B cells, bone marrow-derived dendritic cells and macrophages.
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