TSPYL2

TSPYL2
Identifiers
Aliases	TSPYL2 , CDA1, CINAP, CTCL, DENTT, HRIHFB2216, NP79, SE204, TSPX, TSPY-like 2, TSPY like 2
External IDs	OMIM: 300564 MGI: 106244 HomoloGene: 11140 GeneCards: TSPYL2
Gene location (Human)
Chr.	X chromosome (human)
End	53,088,540 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	151,125,421 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; gastric mucosa; ; tibial nerve; ; left uterine tube; ; canal of the cervix; ; nucleus accumbens; ; sural nerve; ; cingulate gyrus; ; Brodmann area 9; ; ascending aorta;
	Top expressed in
	dorsomedial hypothalamic nucleus; ; superior frontal gyrus; ; paraventricular nucleus of hypothalamus; ; ventromedial nucleus; ; arcuate nucleus; ; cerebellar cortex; ; median eminence; ; lateral hypothalamus; ; suprachiasmatic nucleus; ; ventral tegmental area;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	rDNA binding ; protein binding ;
Cellular component	nucleolus ; nucleoplasm ; nucleus ; cytoplasm ;
Biological process	cell cycle ; nucleosome assembly ; IRE1-mediated unfolded protein response ; negative regulation of cell cycle ; negative regulation of DNA replication ; regulation of protein kinase activity ; regulation of transcription, DNA-templated ; regulation of signal transduction ; negative regulation of cell growth ; transcription, DNA-templated ; chromatin organization ;
	Sources:Amigo / QuickGO
Orthologs
	64061
	52808
	ENSG00000184205
	ENSMUSG00000041096
	Q9H2G4
	Q7TQI8
	NM_022117
	NM_029836 ; NM_145936 ; NM_001358369
	NP_071400
	NP_084112 ; NP_001345298
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated November 29, 2023

Testis-specific Y-encoded-like protein 2 is a protein that in humans is encoded by the TSPYL2 gene.^[5]^[6]^[7]

Related Research Articles

DNA methyltransferase 1-associated protein 1 is an enzyme that in humans is encoded by the DMAP1 gene.

Chloride intracellular channel 4, also known as CLIC4,p644H1,HuH1, is a eukaryotic gene.

NEDD8-activating enzyme E1 catalytic subunit is a protein that in humans is encoded by the UBA3 gene.

Myotrophin is a protein that in humans is encoded by the MTPN gene.

Golgin subfamily A member 3 is a protein that in humans is encoded by the GOLGA3 gene.

GPI transamidase component PIG-T is an enzyme that in humans is encoded by the PIGT gene.

Cdc42 effector protein 3 is a protein that in humans is encoded by the CDC42EP3 gene.

ADP-ribosylation factor-like protein 1 is a protein that in humans is encoded by the ARL1 gene.

BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene.

CGG triplet repeat-binding protein 1 is a protein that in humans is encoded by the CGGBP1 gene.

Sulfiredoxin-1 is a protein that in humans is encoded by the SRXN1 gene.

CpG-binding protein (CGBP) also known as CXXC-type zinc finger protein 1 (CXXC1) or PHD finger and CXXC domain-containing protein 1 (PCCX1) is a protein that in humans is encoded by the CXXC1 gene.

N-terminal acetyltransferase B complex catalytic subunit NAT5 is an enzyme that in humans is encoded by the NAT5 gene.

Uncharacterized hematopoietic stem/progenitor cells protein MDS032, also known as MDS032, is a protein which in humans is encoded by the MDS032 gene.

Actin-binding Rho-activating protein is a protein that in humans is encoded by the ABRA gene. The mouse and rat homologues are known as STARS and MS1 respectively.

28S ribosomal protein L42, mitochondrial is a protein that in humans is encoded by the MRPL42 gene.

Protein MON2 homolog is a protein that in humans is encoded by the MON2 gene.

Gamma-1-syntrophin is a protein that in humans is encoded by the SNTG1 gene.

Zinc finger protein 346 is a protein that in humans is encoded by the ZNF346 gene.

Ras-associating and dilute domain-containing protein is a protein that in humans is encoded by the RADIL gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000184205 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041096 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Ozbun LL, You L, Kiang S, Angdisen J, Martinez A, Jakowlew SB (Apr 2001). "Identification of differentially expressed nucleolar TGF-beta1 target (DENTT) in human lung cancer cells that is a new member of the TSPY/SET/NAP-1 superfamily". Genomics. 73 (2): 179–93. doi:10.1006/geno.2001.6505. PMID 11318608.
↑ Chai Z, Sarcevic B, Mawson A, Toh BH (Sep 2001). "SET-related cell division autoantigen-1 (CDA1) arrests cell growth". J Biol Chem. 276 (36): 33665–74. doi: 10.1074/jbc.M007681200 . PMID 11395479.
↑ "Entrez Gene: TSPYL2 TSPY-like 2".

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948 . PMID 11076863.
Eichmuller S, Usener D, Dummer R, et al. (2001). "Serological detection of cutaneous T-cell lymphoma-associated antigens". Proc. Natl. Acad. Sci. U.S.A. 98 (2): 629–34. doi: 10.1073/pnas.021386498 . PMC 14639 . PMID 11149944.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072 . PMID 11230166.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Wang GS, Hong CJ, Yen TY, et al. (2004). "Transcriptional modification by a CASK-interacting nucleosome assembly protein". Neuron. 42 (1): 113–28. doi: 10.1016/S0896-6273(04)00139-4 . PMID 15066269.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930 . PMID 15489336.
Santama N, Ogg SC, Malekkou A, et al. (2006). "Characterization of hCINAP, a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locus". J. Biol. Chem. 280 (43): 36429–41. doi: 10.1074/jbc.M501982200 . PMID 16079131.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501 . PMID 16381901.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi: 10.1016/j.cell.2006.03.032 . PMID 16713569.
Radke JR, Donald RG, Eibs A, et al. (2006). "Changes in the expression of human cell division autoantigen-1 influence Toxoplasma gondii growth and development". PLOS Pathog. 2 (10): e105. doi: 10.1371/journal.ppat.0020105 . PMC 1626100 . PMID 17069459.
Tu Y, Wu W, Wu T, et al. (2007). "Antiproliferative autoantigen CDA1 transcriptionally up-regulates p21(Waf1/Cip1) by activating p53 and MEK/ERK1/2 MAPK pathways". J. Biol. Chem. 282 (16): 11722–31. doi: 10.1074/jbc.M609623200 . PMID 17317670.

This article on a gene on the human X chromosome and/or its associated protein is a stub. You can help Wikipedia by expanding it.

This page is based on this Wikipedia article
Text is available under the CC BY-SA 4.0 license; additional terms may apply.
Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000184205 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000041096 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11318608-5] Ozbun LL, You L, Kiang S, Angdisen J, Martinez A, Jakowlew SB (Apr 2001). "Identification of differentially expressed nucleolar TGF-beta1 target (DENTT) in human lung cancer cells that is a new member of the TSPY/SET/NAP-1 superfamily". Genomics. 73 (2): 179–93. doi:10.1006/geno.2001.6505. PMID 11318608.

[pmid11395479-6] Chai Z, Sarcevic B, Mawson A, Toh BH (Sep 2001). "SET-related cell division autoantigen-1 (CDA1) arrests cell growth". J Biol Chem. 276 (36): 33665–74. doi: 10.1074/jbc.M007681200 . PMID 11395479.

[entrez-7] "Entrez Gene: TSPYL2 TSPY-like 2".

[1]

[2]

[3]

[4]

[5]

[6]

[7]

TSPYL2

Related Research Articles

References

Further reading