TTC35

EMC2
Identifiers
Aliases	EMC2 , KIAA0103, TTC35, ER membrane protein complex subunit 2
External IDs	OMIM: 607722 MGI: 1913986 HomoloGene: 8785 GeneCards: EMC2
Gene location (Human)
Chr.	Chromosome 8 (human)
End	108,489,196 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	43,391,159 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; corpus callosum; ; sperm; ; right coronary artery; ; body of pancreas; ; islet of Langerhans; ; rectum; ; gastric mucosa; ; optic nerve; ; external globus pallidus;
	Top expressed in
	intercostal muscle; ; digastric muscle; ; facial motor nucleus; ; vastus lateralis muscle; ; sternocleidomastoid muscle; ; myocardium of ventricle; ; triceps brachii muscle; ; temporal muscle; ; right ventricle; ; pineal gland;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding ;
Cellular component	cytoplasm ; EMC complex ; endoplasmic reticulum ; nucleus ;
Biological process	protein folding in endoplasmic reticulum ;
	Sources:Amigo / QuickGO
Orthologs
	9694
	66736
	ENSG00000104412
	ENSMUSG00000022337
	Q15006
	Q9CRD2
	NM_001329493 ; NM_001329494 ; NM_001329495 ; NM_014673
	NM_025736
	NP_001316422 ; NP_001316423 ; NP_001316424 ; NP_055488
	NP_080012
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated January 23, 2024

Tetratricopeptide repeat protein 35 is a protein that in humans is encoded by the TTC35 gene.^[5]^[6]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000104412 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022337 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Nagase T, Miyajima N, Tanaka A, Sazuka T, Seki N, Sato S, Tabata S, Ishikawa K, Kawarabayasi Y, Kotani H, et al. (Jul 1995). "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (1): 37–43. doi: 10.1093/dnares/2.1.37 . PMID 7788527.
↑ "Entrez Gene: TTC35 tetratricopeptide repeat domain 35".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Hoja MR, Wahlestedt C, Höög C (2000). "A visual intracellular classification strategy for uncharacterized human proteins". Exp. Cell Res. 259 (1): 239–46. doi:10.1006/excr.2000.4948. PMID 10942595.
Dreger M, Bengtsson L, Schöneberg T, et al. (2001). "Nuclear envelope proteomics: Novel integral membrane proteins of the inner nuclear membrane". Proc. Natl. Acad. Sci. U.S.A. 98 (21): 11943–8. Bibcode:2001PNAS...9811943D. doi: 10.1073/pnas.211201898 . PMC 59747 . PMID 11593002.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000104412 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022337 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7788527-5] Nagase T, Miyajima N, Tanaka A, Sazuka T, Seki N, Sato S, Tabata S, Ishikawa K, Kawarabayasi Y, Kotani H, et al. (Jul 1995). "Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 2 (1): 37–43. doi: 10.1093/dnares/2.1.37 . PMID 7788527.

[entrez-6] "Entrez Gene: TTC35 tetratricopeptide repeat domain 35".

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TTC35

Related Research Articles

References

Further reading