TTI2

TTI2
Identifiers
Aliases	TTI2 , C8orf41, MRT39, TELO2 interacting protein 2
External IDs	OMIM: 614426 MGI: 2384576 HomoloGene: 11836 GeneCards: TTI2
Gene location (Human)
Chr.	Chromosome 8 (human)
End	33,513,601 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	31,164,702 bp
Orthologs
	80185
	234138
	ENSG00000129696
	ENSMUSG00000031577
	Q6NXR4
	Q8BGV4
	NM_001102401 ; NM_001265581 ; NM_025115 ; NM_001330505
	NM_001112729 ; NM_001199988 ; NM_144927
	NP_001095871 ; NP_001252510 ; NP_001317434 ; NP_079391
	NP_001186917 ; NP_659176
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated December 23, 2020

TELO2 interacting protein 2 is a protein that in humans is encoded by the TTI2 gene. ^[5]

Function

This gene encodes a regulator of the DNA damage response. The protein is a component of the Triple T complex (TTT) which also includes telomere length regulation protein and TELO2 interacting protein 1.

The TTT complex is involved in cellular resistance to DNA damage stresses and may act as a regulator of phosphoinositide-3-kinase-related protein kinase (PIKK) abundance.

Related Research Articles

Casein kinase I isoform epsilon is an enzyme that in humans is encoded by the CSNK1E gene.

ETS domain-containing protein Elk-4 is a protein that in humans is encoded by the ELK4 gene.

AT-rich interactive domain-containing protein 3B is a protein that in humans is encoded by the ARID3B gene.

Adapter protein CIKS is a protein that in humans is encoded by the TRAF3IP2 gene.

Large tumor suppressor kinase 2 (LATS2) is an enzyme that in humans is encoded by the LATS2 gene.

Golgin-45 is a protein that in humans is encoded by the BLZF1 gene.

Zinc finger protein 7 is a protein that in humans is encoded by the ZNF7 gene.

Integrin-linked kinase-associated serine/threonine phosphatase 2C is an enzyme that in humans is encoded by the ILKAP gene.

Diacylglycerol kinase beta is an enzyme that in humans is encoded by the DGKB gene.

Mitogen-activated protein kinase kinase kinase 13 is an enzyme that in humans is encoded by the MAP3K13 gene.

Serine/threonine kinase 35 is a protein that in humans is encoded by the STK35 gene.

A kinase (PRKA) interacting protein 1 is a protein in humans that is encoded by the AKIP1 gene.

Calcium/calmodulin-dependent protein kinase ID is a protein in humans that is encoded by the CAMK1D gene on chromosome 10.

BRCA1-associated ATM activator 1 is a protein in humans that is encoded by the BRAT1 gene.

Polymerase (DNA-directed), epsilon 4, accessory subunit is a protein that in humans is encoded by the POLE4 gene.

Thymidine kinase 2, mitochondrial is a protein that in humans is encoded by the TK2 gene.

Chromatin accessibility complex 1 is a protein that in humans is encoded by the CHRAC1 gene.

GSK3B interacting protein is a protein that in humans is encoded by the GSKIP gene.

Janus kinase and microtubule interacting protein 3 is a protein that in humans is encoded by the JAKMIP3 gene.

Zinc finger protein 2 is a protein that in humans is encoded by the ZNF2 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000129696 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000031577 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: TELO2 interacting protein 2" . Retrieved 2016-12-14.

TTI2

Contents

Function

Related Research Articles

References

Further reading