TUBD1

TUBD1
Identifiers
Aliases	TUBD1 , TUBD, tubulin delta 1
External IDs	OMIM: 607344; MGI: 1891826; HomoloGene: 9443; GeneCards: TUBD1; OMA:TUBD1 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) [1] Band 17q23.1 Start 59,859,479 bp [1] End 59,892,945 bp [1]
Gene location (Mouse) Chr. Chromosome 11 (mouse) [2] Band 11|11 C Start 86,435,817 bp [2] End 86,458,186 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte buccal mucosa cell gonad testicle epithelium of colon ventricular zone body of pancreas Achilles tendon granulocyte tonsil Top expressed in spermatocyte spermatid seminiferous tubule morula zygote muscle of thigh primary oocyte sternocleidomastoid muscle secondary oocyte otic vesicle More reference expression data BioGPS n/a
Gene ontology Molecular function nucleotide binding GTP binding structural constituent of cytoskeleton GTPase activity Cellular component centriole microtubule cytoskeleton nucleus nucleoplasm cytoplasm cytosol cilium cell projection Biological process multicellular organism development microtubule-based process cytoskeleton organization positive regulation of smoothened signaling pathway cell projection organization microtubule cytoskeleton organization mitotic cell cycle Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51174 56427 Ensembl ENSG00000108423 ENSMUSG00000020513 UniProt Q9UJT1 Q9R1K7 RefSeq (mRNA) NM_001193609 NM_001193610 NM_001193611 NM_001193612 NM_001193613 NM_016261 NM_001199045 NM_001199046 NM_001199047 NM_019756 RefSeq (protein) NP_001180538 NP_001180539 NP_001180540 NP_001180541 NP_001180542 NP_057345 NP_001185974 NP_001185975 NP_001185976 NP_062730 Location (UCSC) Chr 17: 59.86 – 59.89 Mb Chr 11: 86.44 – 86.46 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Tubulin, delta 1 is a protein in humans that is encoded by the TUBD1 gene. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000108423 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000020513 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Tubulin, delta 1".

Further reading

• Krebs DL, Uren RT, Metcalf D, Rakar S, Zhang JG, Starr R, De Souza DP, Hanzinikolas K, Eyles J, Connolly LM, Simpson RJ, Nicola NA, Nicholson SE, Baca M, Hilton DJ, Alexander WS (July 2002). "SOCS-6 binds to insulin receptor substrate 4, and mice lacking the SOCS-6 gene exhibit mild growth retardation". Molecular and Cellular Biology. 22 (13): 4567–78. doi:10.1128/MCB.22.13.4567-4578.2002. PMC   133908 . PMID   12052866.
• Kato A, Nagata Y, Todokoro K (May 2004). "Delta-tubulin is a component of intercellular bridges and both the early and mature perinuclear rings during spermatogenesis". Developmental Biology. 269 (1): 196–205. doi:10.1016/j.ydbio.2004.01.026. PMID   15081367.
• Chang P, Stearns T (January 2000). "Delta-tubulin and epsilon-tubulin: two new human centrosomal tubulins reveal new aspects of centrosome structure and function". Nature Cell Biology. 2 (1): 30–5. doi:10.1038/71350. PMID   10620804. S2CID   23500269.
• Sidjanin DJ, Zangerl B, Johnson JL, Xue F, Mellersh C, Ostrander EA, Acland G, Aguirre GD (April 2002). "Cloning of the canine delta tubulin cDNA (TUBD) and mapping to CFA9". Animal Genetics. 33 (2): 161–2. doi:10.1046/j.1365-2052.2002.0831d.x. PMID   12047234.
• Smrzka OW, Delgehyr N, Bornens M (April 2000). "Tissue-specific expression and subcellular localisation of mammalian delta-tubulin". Current Biology. 10 (7): 413–6. doi: 10.1016/s0960-9822(00)00418-8 . PMID   10753753. S2CID   15720739.