TUBG2

TUBG2
Identifiers
Aliases	TUBG2 , tubulin gamma 2
External IDs	OMIM: 605785 MGI: 2144208 HomoloGene: 69216 GeneCards: TUBG2
Gene location (Human)
Chr.	Chromosome 17 (human)
End	42,667,006 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	101,052,613 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; body of pancreas; ; amygdala; ; Brodmann area 9; ; nucleus accumbens; ; caudate nucleus; ; oocyte; ; anterior pituitary; ; tibial nerve; ; gastric mucosa;
	Top expressed in
	secondary oocyte; ; incisor; ; superior frontal gyrus; ; dorsomedial hypothalamic nucleus; ; superior colliculus; ; dorsal tegmental nucleus; ; lateral hypothalamus; ; piriform cortex; ; cerebellar cortex; ; primary motor cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding ; GTP binding ; structural molecule activity ; GTPase activity ; structural constituent of cytoskeleton ;
Cellular component	cytoplasm ; microtubule cytoskeleton ; microtubule organizing center ; cytoplasmic microtubule ; cytosol ; centrosome ; spindle microtubule ; gamma-tubulin complex ; pericentriolar material ; cytoskeleton ; microtubule ; nucleus ; spindle ;
Biological process	cytoplasmic microtubule organization ; microtubule nucleation ; microtubule-based process ; mitotic sister chromatid segregation ; meiotic spindle organization ; microtubule cytoskeleton organization ; mitotic cell cycle ; mitotic spindle organization ;
	Sources:Amigo / QuickGO
Orthologs
	27175
	103768
	ENSG00000037042
	ENSMUSG00000045007
	Q9NRH3
	Q8VCK3
	NM_016437 ; NM_001320509
	NM_134028
	NP_001307438 ; NP_057521
	NP_598789
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated November 08, 2023

Tubulin gamma-2 chain is a protein that in humans is encoded by the TUBG2 gene.^[5]

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000037042 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000045007 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: TUBG2 tubulin, gamma 2".

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Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Tassin AM, Celati C, Moudjou M, Bornens M (1998). "Characterization of the human homologue of the yeast spc98p and its association with gamma-tubulin". J. Cell Biol. 141 (3): 689–701. doi:10.1083/jcb.141.3.689. PMC 2132749 . PMID 9566969.
Herreros L, Rodríguez-Fernandez JL, Brown MC, et al. (2000). "Paxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeleton". J. Biol. Chem. 275 (34): 26436–40. doi: 10.1074/jbc.M003970200 . hdl: 10261/135387 . PMID 10840040.
Wise DO, Krahe R, Oakley BR (2000). "The gamma-tubulin gene family in humans". Genomics. 67 (2): 164–70. doi:10.1006/geno.2000.6247. PMID 10903841.
Niwa J, Ishigaki S, Doyu M, et al. (2001). "A novel centrosomal ring-finger protein, dorfin, mediates ubiquitin ligase activity". Biochem. Biophys. Res. Commun. 281 (3): 706–13. doi:10.1006/bbrc.2001.4414. PMID 11237715.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Chang F, Re F, Sebastian S, et al. (2004). "HIV-1 Vpr induces defects in mitosis, cytokinesis, nuclear structure, and centrosomes". Mol. Biol. Cell. 15 (4): 1793–801. doi:10.1091/mbc.E03-09-0691. PMC 379276 . PMID 14767062.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000037042 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000045007 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: TUBG2 tubulin, gamma 2".

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TUBG2

Related Research Articles

References

Further reading