Ruiz is best known for portraying cartel queen Isabella Bautista in the first two seasons of Narcos: Mexico as well as Maria in the American comedy-drama television series Mo that premiered on on Netflix. In 2022 Ruiz starred in the biographicaldrama filmFather Stu opposite Mark Wahlberg and Mel Gibson. Ruiz has been awarded several Best Actress awards internationally and is a Lifetime Member of the Actors Studio.
In 2022 Ruiz starred in the film Noise (Spanish: Ruido) a Mexican-Argentine drama film directed by Natalia Beristáin and written by Beristáin, Diego Enrique Osorno & Alo Valenzuela Escobedo. The film won the Spanish Cooperation Award at the San Sebastián International Film Festival.
She also played the character Nadia Basurto in the political thriller Aquí en la Tierra[2] a co-production between Gael Garcia Bernal and Diego Luna's production company La Corriente del Golfo and Fox Networks. The 8-episode drama series written and directed by some of Mexico's most renowned filmmakers was the only Latin American title competing in the inaugural edition of Cannes Film Festival: Series.[3]
Ruiz went on to play the main character in Gerardo Tort's Round Trip (or Viaje Redondo in Spanish), for which she won several Best Actress awards including the Guadalajara's International Film Festival's Mayahuel, the Prix d'Interprétation Féminine at the Amiens International Film Festival in France and the India Catalina in Colombia; as well as Mexico's Academy Award: Ariel.
She also played young Frida Kahlo in Ofelia Medina's Cada Quien su Frida; the play had its worldwide premiere at the International Cadiz Theater Festival in Spain, then went on to tour in Cuba, Denmark, the UK, Mexico and the US.
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