Tetrahydrocoptisine

Last updated
Tetrahydrocoptisine
Tetrahydrocoptisine.svg
Names
IUPAC name
5,7,17,19-tetraoxa-13-azahexacyclo[11.11.0.02,10.04,8.015,23.016,20]tetracosa-2,4(8),9,15(23),16(20),21-hexaene
Other names
Stylopine
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
KEGG
PubChem CID
UNII
  • InChI=1S/C19H17NO4/c1-2-16-19(24-10-21-16)14-8-20-4-3-12-6-17-18(23-9-22-17)7-13(12)15(20)5-11(1)14/h1-2,6-7,15H,3-5,8-10H2
    Key: UXYJCYXWJGAKQY-UHFFFAOYSA-N
  • C1CN2CC3=C(CC2C4=CC5=C(C=C41)OCO5)C=CC6=C3OCO6
Properties
C19H17NO4
Molar mass 323.348 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Tetrahydrocoptisine (also known as stylopine) is an alkaloid isolated from Corydalis impatiens . [1]

References

  1. ↑ Li, W.; Huang, H.; Zhang, Y.; Fan, T.; Liu, X.; Xing, W.; Niu, X. (2013). "Anti-inflammatory effect of tetrahydrocoptisine from Corydalis impatiens is a function of possible inhibition of TNF-α, IL-6 and NO production in lipopolysaccharide-stimulated peritoneal macrophages through inhibiting NF-κB activation and MAPK pathway". European Journal of Pharmacology. 715 (1–3): 62–71. doi:10.1016/j.ejphar.2013.06.017. PMID   23810685.
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