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Fentanyl is a potent synthetic piperidine opioid primarily used as an analgesic. It is 50 times more potent than heroin and 100 times more potent than morphine; its primary clinical utility is in pain management for cancer patients and those recovering from painful surgeries. Fentanyl is also used as a sedative. Depending on the method of delivery, fentanyl can be very fast acting and ingesting a relatively small quantity can cause overdose. Fentanyl works by activating μ-opioid receptors. Fentanyl is sold under the brand names Actiq, Duragesic and Sublimaze, among others.
Sufentanil, sold under the brand names Dsuvia and Sufenta, is a synthetic opioid analgesic drug approximately 5 to 10 times as potent as its parent drug, fentanyl, and 500 times as potent as morphine. Structurally, sufentanil differs from fentanyl through the addition of a methoxymethyl group on the piperidine ring, and the replacement of the phenyl ring by thiophene. Sufentanil first was synthesized at Janssen Pharmaceutica in 1974.
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References
- ↑ "3 Podcasts to Listen to in July". Podcast Review. July 5, 2023. Archived from the original on July 7, 2023. Retrieved July 12, 2023.
- ↑ IV, Daniel Figueroa (June 30, 2023). "'How could this happen at Yale?': Serial podcast features women whose pain meds were swapped at fertility clinic". CT Insider. Archived from the original on July 8, 2023. Retrieved July 12, 2023.
- ↑ "The Retrievals podcast explores 'living nightmare' at Yale fertility clinic – Rodina News". July 3, 2023. Archived from the original on July 19, 2023. Retrieved July 12, 2023.
- ↑ Sawyer, Miranda (July 8, 2023). "The week in audio: Into the Dirt; The Retrievals; Taste; Walt Disney: A Life in Films – review". The Guardian. ISSN 0261-3077. Archived from the original on July 10, 2023. Retrieved July 12, 2023.
- ↑ Gupta, Neksha (July 9, 2023). "Donna Monticone Controversy and Scandal: Yale Fentanyl Clinic Lawsuit Explained". PKB News. Archived from the original on July 4, 2023. Retrieved July 12, 2023.
- ↑ Brown, Natalie. "New podcast The Retrievals explores 'living nightmare' at Yale fertility clinic". Archived from the original on July 3, 2023. Retrieved July 12, 2023.
- ↑ IV, Daniel Figueroa (June 30, 2023). "'How could this happen at Yale?': Serial podcast features women whose pain meds were swapped at fertility clinic". New Haven Register. Archived from the original on July 5, 2023. Retrieved July 12, 2023.
- ↑ Sturges, Fiona (July 10, 2023). "Women denied pain relief tell their stories in podcast The Retrievals — review". Financial Times. Archived from the original on July 11, 2023. Retrieved July 12, 2023.
- ↑ Quah, Nicholas (December 7, 2023). "The Best Podcasts of 2023 Despite a tough year for the industry, the podcast world remains vast in its pleasures". Vulture.
- ↑ Dockterman, Eliana (November 22, 2023). "The 10 Best Podcasts of 2023". Time Magazine.
