Thomas Schwarz

Last updated
Thomas Schwarz
Born
NationalityAmerican
Alma mater Harvard College, Harvard Medical School
Scientific career
Fields Genetics, neurobiology
Institutions Harvard University
Doctoral advisor Edward Kravitz

Thomas L Schwarz is an American neuroscientist and molecular biology researcher at Children's Hospital, Boston, [1] and a Professor of Neurology and Neurobiology in the Department of Neurobiology at Harvard Medical School. [2]

Neuroscientist Individual who studies neuroscience

A neuroscientist is a scientist who has specialised knowledge in the field of neuroscience, the branch of biology that deals with the physiology, biochemistry, anatomy and molecular biology of neurons and neural circuits and especially their association with behaviour and learning.

Molecular biology Branch of biology dealing with biological activitys molecular basis

Molecular biology is a branch of biology that concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, proteins and their biosynthesis, as well as the regulation of these interactions.

Boston Childrens Hospital Hospital in Massachusetts, United States

Boston Children's Hospital is a 404-licensed-bed children's hospital in the Longwood Medical and Academic Area of Boston, Massachusetts. At 300 Longwood Avenue, Children's is adjacent both to its teaching affiliate, Harvard Medical School, and to Dana-Farber Cancer Institute. Dana-Farber and Children's jointly operate Dana-Farber/Children's Hospital Cancer Care to deliver comprehensive care to patients and survivors of all types of childhood cancers.

Thomas Schwarz is best known for discovering and characterizing the Drosophila protein Milton. [3] This protein has been shown to be crucial to mitochondrial localization to the nerve terminal.

<i>Drosophila melanogaster</i> Species of fruit fly

Drosophila melanogaster is a species of fly in the family Drosophilidae. The species is known generally as the common fruit fly or vinegar fly. Starting with Charles W. Woodworth's proposal of the use of this species as a model organism, D. melanogaster continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution. As of 2017, eight Nobel prizes had been awarded for research using Drosophila.

Education

Thomas Schwarz graduated from Harvard College, where he was heavily involved with the college's WHRB radio, before earning a PhD from Harvard Medical School. His doctoral advisor was scientist Edward Kravitz.

Harvard College Main undergraduate school of Harvard University in Cambridge, Massachusetts

Harvard College is the undergraduate liberal arts college of Harvard University. Founded in 1636 in Cambridge, Massachusetts, it is the oldest institution of higher learning in the United States and one of the most prestigious in the world.

WHRB is a commercial FM radio station in Cambridge, Massachusetts. It broadcasts at 95.3 MHz and is operated by students at Harvard College.

Harvard Medical School Medical school in Boston, MA

Harvard Medical School (HMS) is the graduate medical school of Harvard University. It is located in the Longwood Medical Area of the Mission Hill neighborhood in Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is ranked first among research-oriented medical schools in the 2020 rankings of U.S. News and World Report. Unlike most other leading medical schools, HMS does not operate in conjunction with a single hospital but is directly affiliated with several teaching hospitals in the Boston area. The HMS faculty has approximately 2,900 full- and part-time voting faculty members consisting of assistant, associate, and full professors, and over 5,000 full- and part-time, non-voting instructors. The majority of the faculty receive their appointments through an affiliated teaching hospital.

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Beth Israel Deaconess Medical Center Hospital in Massachusetts, United States

Beth Israel Deaconess Medical Center (BIDMC) in Boston, Massachusetts is a teaching hospital of Harvard Medical School. It was formed out of the 1996 merger of Beth Israel Hospital and New England Deaconess Hospital. Among independent teaching hospitals, Beth Israel Deaconess Medical Center consistently ranks in the top three recipients of biomedical research funding from the National Institutes of Health. Research funding totals nearly $200 million annually. BIDMC researchers run more than 850 active sponsored projects and 200 clinical trials. The Harvard-Thorndike General Clinical Research Center, the oldest clinical research laboratory in the United States, has been located on this site since 1973.

Linda B. Buck American biologist

Linda Brown Buck is an American biologist best known for her work on the olfactory system. She was awarded the 2004 Nobel Prize in Physiology or Medicine, along with Richard Axel, for their work on olfactory receptors. She is currently on the faculty of the Fred Hutchinson Cancer Research Center in Seattle.

Dr. Sharmila Bhattacharya is the Chief Scientist for Astrobionics and head of the Biomodel Performance and Behavior laboratory at NASA Ames Research Center.

John Heuser American biologist

John E. Heuser is an American Professor of Biophysics in the department of Cell Biology and Physiology at the Washington University School of Medicine as well as a Professor at the Institute for Integrated Cell-Matieral Sciences (iCeMS) at Kyoto University. Heuser created quick-freeze deep-etch electron microscopy, a pioneering technique that lets biologists take detailed pictures of fleeting events inside living cells. For decades, Heuser has used this technique to capture details of the molecular mechanisms that underlie many basic biological activities, including nerve cell signal transmission, muscle contraction, and most recently, the fusion of viruses with cells during the spread of infection. He compares quick-freeze deep-etch electron microscopy to using a stroboscopic flash to freeze the action in a photograph. To make it possible to image the frozen sample with an electron microscope, Heuser adds an ultra-thin film of metallic platinum that molds snugly against the sample's frozen surface contours. He and others in his lab have worked to make the equipment and procedures necessary for this process available to researchers around the world. Currently Heuser has patents pending on Washington University's behalf for even more advanced versions of his quick-freezing machines. Heuser graduated magna cum laude from Harvard Medical School in 1969 and joined the Washington University faculty as a professor of biophysics in 1980. He is currently associate editor of the Journal of Neurocytology and previously served as associate editor of the Journal of Cell Biology. His curriculum vitae lists over 200 scientific publications. He was elected as a fellow of the American Academy of Arts and Sciences class of 2005 and of the American Association for the Advancement of Science in 2007. Heuser was also elected as a member of the National Academy of Sciences in 2011.

Rachel Wilson is a professor of neurobiology at Harvard Medical School. Wilson's work integrates electrophysiology, neuropharmacology, molecular genetics, functional anatomy, and behavior to explore how neural circuits are organized to react and sense a complex environment.

Axon terminal Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.

Axon terminals are distal terminations of the telodendria (branches) of an axon. An axon, also called a nerve fiber, is a long, slender projection of a nerve cell, or neuron, that conducts electrical impulses called action potentials away from the neuron's cell body, or soma, in order to transmit those impulses to other neurons, muscle cells or glands.

Steven M. Reppert is an American neuroscientist known for his contributions to the fields of chronobiology and neuroethology. His research has focused primarily on the physiological, cellular, and molecular basis of circadian rhythms in mammals and more recently on the navigational mechanisms of migratory monarch butterflies. He was the Higgins Family Professor of Neuroscience at the University of Massachusetts Medical School from 2001 to 2017, and from 2001 to 2013 was the founding chair of the Department of Neurobiology. Reppert stepped down as chair in 2014. He is currently distinguished professor emeritus of neurobiology.

Andrea Hilary Brand is the Herchel Smith Professor of Molecular Biology and a Fellow of Jesus College, Cambridge. She heads a lab investigating nervous system development at the Gurdon Institute and the Department of Physiology, Development and Neuroscience. She developed the GAL4/UAS system with Norbert Perrimon which has been described as “a fly geneticist's Swiss army knife”.

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Christine Elizabeth Holt FRS, FMedSci is a British developmental neuroscientist.

Norbert Perrimon is a geneticist and developmental biologist at Harvard Medical School. He is known for developing a number of techniques for use of Drosophila, as well as specific substantive contributions to signal transduction and developmental biology. Perrimon co-developed the GAL4/UAS system method, described as “a fly geneticist's Swiss army knife”, with Andrea Brand to control gene expression. With Tze-bin Chou he developed the FLP-FRT DFS method to analyze the maternal effect of zygotic lethal mutations. With Jianquan Ni, he developed and improved methods for in vivo RNAi. His lab has pioneered high-throughput whole-genome RNAi screening.

Daniel Wolpert British neuroscientist

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Michael W. Young American geneticist, cronobiologist

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Rao Yi is a Chinese neurobiologist. A graduate of the University of California, San Francisco, Rao held a Helen Hay Whitney fellowship at Harvard University and was on the faculty of Washington University in St. Louis and Northwestern University before moving back to China to take up the deanship of Peking University's School of Life Sciences in 2007. He is currently the director the IDG/McGovern Institute for Brain Research at Peking University. He took office as the President of the Capital Medical University in June 25th, 2019.

Ian Anthony Meinertzhagen is a Canadian neurobiologist, a University Research Professor at Dalhousie University, in Halifax, Nova Scotia and Senior Fellow at the Janelia Research Campus of the Howard Hughes Medical Institute in Ashburn, Virginia. He is a graduate of the Universities of Aberdeen (BSc) and St. Andrews and undertook postdoctoral work at the Australian National University and Harvard University. His research has pioneered studies on simple nervous systems of invertebrate species, especially the Drosophila visual system and the diminutive chordate nervous system of the ascidian tadpole larva,.

Department of Neurobiology, Harvard Medical School

The Department of Neurobiology at Harvard Medical School is located in the Longwood Medical Area of Boston, MA. It is consistently ranked as one of the top programs in Neurobiology and behavior in the world. The Department is part of the Basic Research Program at Harvard Medical School, with research pertaining to development of the nervous system, sensory neuroscience, neurophysiology, and behavior. The Department was founded by Stephen W. Kuffler in 1966, the first department dedicated to Neurobiology in the world. The mission of the Department is “ to understand the workings of the brain through basic research and to use that knowledge to work toward preventive and therapeutic methods that alleviate neurological diseases”.

Bernardo L. Sabatini is an American neuroscientist who is the Alice and Rodman W. Moorhead III Professor of Neurobiology at Harvard Medical School.

Liqun Luo is a neuroscientist in the Department of Biology at Stanford University, where he is the Ann and Bill Swindells Professor in the School of Humanities and Sciences, and an investigator of the Howard Hughes Medical Institute. His laboratory studies the development and organization of neural circuits, and he is the author of the textbook Principles of Neurobiology.

References

  1. CHB. "CHB". CHB. Archived from the original on 24 July 2008. Retrieved 6 January 2013.
  2. Harvard Medical School. "HMS". Harvard. Retrieved 6 January 2013.
  3. Stowers, Steven; Laura J. Megeath; Jolanta Górska-Andrzejak; Ian A. Meinertzhagen; Thomas L. Schwarz (12 December 2002). "Axonal Transport of Mitochondria to Synapses Depends on Milton, a Novel Drosophila Protein". Neuron. 36 (6): 1063–1077. doi:10.1016/S0896-6273(02)01094-2.