Thrombospondin-3 (TSP3) is a protein that in humans is encoded by the THBS3 gene. [5] [6]
The protein encoded by this gene belongs to the thrombospondin family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. TSP3 has been found to be involved in the regulation of skeletal maturation. [7] This protein forms a pentameric molecule linked by a single disulfide bond. This gene shares a common promoter with metaxin 1. [6]
Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor.
Collagen alpha-1(V) chain is a protein that in humans is encoded by the COL5A1 gene.
Dual specificity mitogen-activated protein kinase kinase 2 is an enzyme that in humans is encoded by the MAP2K2 gene. It is more commonly known as MEK2, but has many alternative names including CFC4, MKK2, MAPKK2 and PRKMK2.
Protein kinase C eta type is an enzyme that in humans is encoded by the PRKCH gene.
A disintegrin and metalloproteinase with thrombospondin motifs 1 is an enzyme that in humans is encoded by the ADAMTS1 gene.
Disintegrin and metalloproteinase domain-containing protein 9 is an enzyme that in humans is encoded by the ADAM9 gene.
Thrombospondin-2 is a protein that in humans is encoded by the THBS2 gene.
Eukaryotic translation initiation factor 2 subunit 2 (eIF2β) is a protein that in humans is encoded by the EIF2S2 gene.
Tropomodulin-1 is a protein that in humans is encoded by the TMOD1 gene.
Syntaxin-binding protein 2 is a protein that in humans is encoded by the STXBP2 gene.
Cytoplasmic dynein 1 intermediate chain 1 is a protein that in humans is encoded by the DYNC1I1 gene.
Thrombospondin-4 is a protein that in humans is encoded by the THBS4 gene.
MAP kinase-activated protein kinase 5 is an enzyme that in humans is encoded by the MAPKAPK5 gene. The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases, including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately-spliced transcript variants of this gene encoding distinct isoforms have been reported.
Myosin-XVIIIa is a protein that in humans is encoded by the MYO18A gene.
Metaxin 1, also known as MTX1, is a protein which in humans is encoded by the MTX1 gene.
A disintegrin and metalloproteinase with thrombospondin motifs 9 is an enzyme that in humans is encoded by the ADAMTS9 gene.
Dynein, light chain, Tctex-type 3, also known as DYNLT3, is a protein which in humans is encoded by the DYNLT3 gene.
A disintegrin and metalloproteinase with thrombospondin motifs 10 is an enzyme that in humans is encoded by the ADAMTS10 gene.
Protein kinase C-binding protein NELL2 is an enzyme that in humans is encoded by the NELL2 gene.
Lamin-B1 is a protein that in humans is encoded by the LMNB1 gene.
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