UBASH3A

Last updated
UBASH3A
Protein UBASH3A PDB 2crn.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases UBASH3A , CLIP4, STS-2, TULA, TULA-1, ubiquitin associated and SH3 domain containing A
External IDs OMIM: 605736 MGI: 1926074 HomoloGene: 56833 GeneCards: UBASH3A
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001001895
NM_001243467
NM_018961

NM_177823

RefSeq (protein)

NP_001001895
NP_001230396
NP_061834

NP_808491

Location (UCSC) Chr 21: 42.4 – 42.45 Mb Chr 17: 31.43 – 31.47 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Ubiquitin-associated and SH3 domain-containing protein A is a protein that in humans is encoded by the UBASH3A gene. [5] [6]


Related Research Articles

UBA1

Ubiquitin-like modifier activating enzyme 1 (UBA1) is an enzyme which in humans is encoded by the UBA1 gene. UBA1 participates in ubiquitination and the NEDD8 pathway for protein folding and degradation, among many other biological processes. This protein has been linked to X-linked spinal muscular atrophy type 2, neurodegenerative diseases, and cancers.

ACVR1C

The activin A receptor also known as ACVR1C or ALK-7 is a protein that in humans is encoded by the ACVR1C gene. ACVR1C is a type I receptor for the TGFB family of signaling molecules.

CBL (gene) Mammalian gene

Cbl is a mammalian gene encoding the protein CBL which is an E3 ubiquitin-protein ligase involved in cell signalling and protein ubiquitination. Mutations to this gene have been implicated in a number of human cancers, particularly acute myeloid leukaemia.

Baculoviral IAP repeat-containing protein 3

Baculoviral IAP repeat-containing protein3 is a protein that in humans is encoded by the BIRC3 gene.

CBLB (gene)

CBL-B is an E3 ubiquitin-protein ligase that in humans is encoded by the CBLB gene. CBLB is a member of the CBL gene family.

TP53BP2

Apoptosis-stimulating of p53 protein 2 (ASPP2) also known as Bcl2-binding protein (Bbp) and tumor suppressor p53-binding protein 2 (p53BP2) is a protein that in humans is encoded by the TP53BP2 gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Ubiquitin A-52 residue ribosomal protein fusion product 1 Human protein

60S ribosomal protein L40 (RPL40) is a protein that in humans is encoded by the UBA52 gene.

SH3GL2

Endophilin-A1 is a protein that in humans is encoded by the SH3GL2 gene.

FAF1

FAS-associated factor 1 is a protein that in humans is encoded by the FAF1 gene.

SERPINB9

Serpin B9 is a protein that in humans is encoded by the SERPINB9 gene. PI9 belongs to the large superfamily of serine proteinase inhibitors (serpins), which bind to and inactivate serine proteinases. These interactions are involved in many cellular processes, including coagulation, fibrinolysis, complement fixation, matrix remodeling, and apoptosis .[supplied by OMIM]

RNF7

RING-box protein 2 is a protein that in humans is encoded by the RNF7 gene.

SNX9

Sorting nexin-9 is a protein that in humans is encoded by the SNX9 gene.

SH3GL1

Endophilin-A2 is a protein that in humans is encoded by the SH3GL1 gene.

UBE1C

NEDD8-activating enzyme E1 catalytic subunit is a protein that in humans is encoded by the UBA3 gene.

CBLC

Signal transduction protein CBL-C is a protein that in humans is encoded by the CBLC gene.

STS-1 (gene) Protein-coding gene in the species Homo sapiens

Ubiquitin-associated and SH3 domain-containing protein B is a protein that in humans is encoded by the UBASH3B gene.

UBE1L

Ubiquitin-like modifier-activating enzyme 7 is a protein that in humans is encoded by the UBA7 gene.

PACSIN3

Protein kinase C and casein kinase substrate in neurons protein 3 is an enzyme that in humans is encoded by the PACSIN3 gene.

UBE2M

NEDD8-conjugating enzyme Ubc12 is a protein that in humans is encoded by the UBE2M gene.

SOCS6

Suppressor of cytokine signaling 6 is a protein that in humans is encoded by the SOCS6 gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000160185 - Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042345 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Wattenhofer M, Shibuya K, Kudoh J, Lyle R, Michaud J, Rossier C, Kawasaki K, Asakawa S, Minoshima S, Berry A, Bonne-Tamir B, Shimizu N, Antonarakis SE, Scott HS (Apr 2001). "Isolation and characterization of the UBASH3A gene on 21q22.3 encoding a potential nuclear protein with a novel combination of domains". Hum Genet. 108 (2): 140–7. doi:10.1007/s004390000453. PMID   11281453. S2CID   22719211.
  6. "Entrez Gene: UBASH3A ubiquitin associated and SH3 domain containing, A".

Further reading