UBOX5

UBOX5
Identifiers
Aliases	UBOX5 , RNF37, UBCE7IP5, UIP5, hUIP5, U-box domain containing 5
External IDs	MGI: 2154658 HomoloGene: 8972 GeneCards: UBOX5
Gene location (Human) Chr. Chromosome 20 (human) [1] Band 20p13 Start 3,107,573 bp [1] End 3,160,196 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2 F1|2 Start 130,431,922 bp [2] End 130,471,958 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in parotid gland gastrocnemius muscle skeletal muscle tissue blood Region I of hippocampus proper popliteal artery inferior olivary nucleus middle temporal gyrus stromal cell of endometrium Brodmann area 23 Top expressed in otic placode spermatocyte female urethra maxillary prominence saccule internal carotid artery external carotid artery somite proximal tubule quadriceps femoris muscle More reference expression data BioGPS n/a
Gene ontology Molecular function ubiquitin-ubiquitin ligase activity protein binding ubiquitin protein ligase binding metal ion binding ubiquitin protein ligase activity ubiquitin-protein transferase activity transferase activity Cellular component nuclear body nucleus nucleoplasm focal adhesion Biological process protein polyubiquitination protein ubiquitination Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 22888 140629 Ensembl ENSG00000185019 ENSMUSG00000027300 UniProt O94941 Q925F4 RefSeq (mRNA) NM_199415 NM_001267584 NM_014948 NM_001255993 NM_001255994 NM_080562 RefSeq (protein) NP_001254513 NP_055763 NP_955447 NP_001242922 NP_001242923 NP_542129 Location (UCSC) Chr 20: 3.11 – 3.16 Mb Chr 2: 130.43 – 130.47 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

RING finger protein 37 is a protein that in humans is encoded by the UBOX5 gene. ^{[5] [6]}

Interactions

UBOX5 has been shown to interact with UBE2L3. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000185019 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000027300 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Pringa E, Martinez-Noel G, Muller U, Harbers K (May 2001). "Interaction of the ring finger-related U-box motif of a nuclear dot protein with ubiquitin-conjugating enzymes". J Biol Chem. 276 (22): 19617–23. doi: 10.1074/jbc.M100192200 . PMID   11274149.
6. "Entrez Gene: UBOX5 U-box domain containing 5".

Further reading

• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID   8125298.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID   9373149.
• Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (6): 355–64. doi: 10.1093/dnares/5.6.355 . PMID   10048485.
• Martinez-Noel G, Niedenthal R, Tamura T, Harbers K (1999). "A family of structurally related RING finger proteins interacts specifically with the ubiquitin-conjugating enzyme UbcM4". FEBS Lett. 454 (3): 257–61. Bibcode:1999FEBSL.454..257M. doi: 10.1016/S0014-5793(99)00823-6 . PMID   10431818. S2CID   46159115.
• Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID   16189514. S2CID   4427026.