UBP1

UBP1
Identifiers
Aliases	UBP1 , LBP-1B, LBP-1a, LBP1A, LBP1B, upstream binding protein 1 (LBP-1a), upstream binding protein 1
External IDs	OMIM: 609784 MGI: 104889 HomoloGene: 8435 GeneCards: UBP1
Gene location (Human)
Chr.	Chromosome 3 (human)
End	33,441,371 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	113,806,270 bp
RNA expression pattern
	Top expressed in
	tibia; ; rectum; ; sural nerve; ; visceral pleura; ; popliteal artery; ; appendix; ; right coronary artery; ; smooth muscle tissue; ; endothelial cell; ; lymph node;
	Top expressed in
	Paneth cell; ; medullary collecting duct; ; secondary oocyte; ; ureter; ; renal corpuscle; ; saccule; ; substantia nigra; ; condyle; ; fossa; ; retinal pigment epithelium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding ; transcription corepressor activity ; sequence-specific DNA binding ; DNA-binding transcription factor activity ; DNA-binding transcription factor activity, RNA polymerase II-specific ;
Cellular component	nucleus ; nucleoplasm ; cytosol ;
Biological process	viral genome replication ; negative regulation of transcription, DNA-templated ; regulation of transcription, DNA-templated ; angiogenesis ; transcription, DNA-templated ; regulation of transcription by RNA polymerase II ;
	Sources:Amigo / QuickGO
Orthologs
	7342
	22221
	ENSG00000153560
	ENSMUSG00000009741
	Q9NZI7
	Q811S7
	NM_001128160 ; NM_001128161 ; NM_014517
NM_001083319 ; NM_013699 ; NM_001372507 ; NM_001372508 ; NM_001372510 ;
	NM_001372511 ; NM_001372512 ; NM_001372514
	NP_001121632 ; NP_001121633 ; NP_055332
NP_001076788 ; NP_038727 ; NP_001359436 ; NP_001359437 ; NP_001359439 ;
	NP_001359440 ; NP_001359441 ; NP_001359443
	Wikidata
View/Edit Human	View/Edit Mouse

Last updated March 04, 2023

Upstream-binding protein 1 is a protein that in humans is encoded by the UBP1 gene.^[5]^[6]

Related Research Articles

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Transcription initiation factor TFIID subunit 4 is a protein that in humans is encoded by the TAF4 gene.

Transcription initiation factor TFIID subunit 2 is a protein that in humans is encoded by the TAF2 gene.

Transcription initiation factor TFIID subunit 10 is a protein that in humans is encoded by the TAF10 gene.

Transcription initiation factor TFIID subunit 5 is a protein that in humans is encoded by the TAF5 gene.

Transcription initiation factor TFIID subunit 11 also known as TAFII28, is a protein that in humans is encoded by the TAF11 gene.

TATA-binding protein-associated factor 2N is a protein that in humans is encoded by the TAF15 gene.

General transcription factor 3C polypeptide 2 is a protein that in humans is encoded by the GTF3C2 gene.

TATA-binding protein-associated factor 172 is a protein that in humans is encoded by the BTAF1 gene.

Transcription initiation factor TFIID subunit 13 is a protein that in humans is encoded by the TAF13 gene.

Transcription initiation factor TFIID subunit 8 is a protein that in humans is encoded by the TAF8 gene.

Chorion-specific transcription factor GCMa is a protein that, in humans, is encoded by the GCM1 gene.

Mediator of RNA polymerase II transcription subunit 17 is an enzyme that in humans is encoded by the MED17 gene.

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References

1 2 3 GRCh38: Ensembl release 89: ENSG00000153560 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000009741 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Yoon JB, Li G, Roeder RG (Mar 1994). "Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro". Mol Cell Biol. 14 (3): 1776–85. doi:10.1128/mcb.14.3.1776. PMC 358535 . PMID 8114710.
↑ "Entrez Gene: UBP1 upstream binding protein 1 (LBP-1a)".

Kato H, Horikoshi M, Roeder RG (1991). "Repression of HIV-1 transcription by a cellular protein". Science. 251 (5000): 1476–9. Bibcode:1991Sci...251.1476K. doi:10.1126/science.2006421. PMID 2006421.
Parada CA, Yoon JB, Roeder RG (1995). "A novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro". J. Biol. Chem. 270 (5): 2274–83. doi: 10.1074/jbc.270.5.2274 . PMID 7836461.
Huang N, Miller WL (2000). "Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc". J. Biol. Chem. 275 (4): 2852–8. doi: 10.1074/jbc.275.4.2852 . PMID 10644752.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi: 10.1038/ng1285 . PMID 14702039.
Zhao H, Li J, Jiang L (2004). "Inhibition of HIV-1 TAR RNA-Tat peptide complexation using poly(acrylic acid)". Biochem. Biophys. Res. Commun. 320 (1): 95–9. doi:10.1016/j.bbrc.2004.05.148. PMID 15207707.
Huang N, Miller WL (2005). "LBP proteins modulate SF1-independent expression of P450scc in human placental JEG-3 cells". Mol. Endocrinol. 19 (2): 409–20. doi: 10.1210/me.2004-0086 . PMID 15471945.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928 . PMID 15489334.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000153560 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000009741 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8114710-5] Yoon JB, Li G, Roeder RG (Mar 1994). "Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro". Mol Cell Biol. 14 (3): 1776–85. doi:10.1128/mcb.14.3.1776. PMC 358535 . PMID 8114710.

[entrez-6] "Entrez Gene: UBP1 upstream binding protein 1 (LBP-1a)".

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UBP1

Related Research Articles

References

Further reading